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Faculty

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Debra A. Tonetti, PhD, Interim Department Head, Professor of Pharmacology

dtonetti@uic.edu, Office (312) 413-1169, Lab (312) 996-9779

Research Interests: Pharmacology and biology of breast cancer including mechanisms of endocrine-resistance and pregnancy-associated breast cancer. Protein Kinase C signaling as a mechanism of tamoxifen-resistant breast cancer. Pregnancy Associated Breast Cancer. Interaction of soy phytoestrogens with tamoxifen for the chemoprevention of breast cancer. 

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Maria V. Barbolina, PhD, Associate Professor of Pharmacology

mvb@uic.edu, Office (312) 335-0670, Lab (312) 335-5487

Research Interests: Microenvironmental regulation of ovarian carcinoma metastasis. Signal transduction pathways. Mechanisms of chemoresistance.
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William T. Beck, PhD, UIC Distinguished Professor, Professor of Pharmacology and Molecular Genetics

wtbeck@uic.edu, Office (312) 996-0888

Research Interests: Molecular pharmacology and genetics of anticancer drug action and tumor cell drug resistance. Action of and tumor cell resistance to inhibitors of the DNA topoisomerases. Molecular mechanisms of regulation of genes associated with multidrug resistance in cancer. Role of splicing factors in tumorigenesis and anticancer drug action.

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Richard A. Gemeinhart, PhD, Professor of Pharmaceutics and Bioengineering, Research Integrity Officer, Director of Graduate Studies - BPS

rag@uic.edu, Office (312) 996-2253, Lab (312) 996-9765
Lab webpage 

Research Interests: Tissue Regeneration. Micro/Nanostructures. Therapeutic Drug Conjugates. We are interested in designing polymers that interact with cells to elicit a desired biologic response. We currently have projects in the areas of cellular differentiation and cancer treatment. By utilizing and mimicking biologic interactions into synthetic polymers, the desired properties of the polymer can be exploited. The biologic motifs allow the cells or tissue to respond in a natural manner to the polymer resulting in more natural regeneration, regrowth, or cellular death.

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Leslyn Hanakahi, PhD, Associate Professor of Pharmacology

hanakahi@uic.edu, Office (815) 395-5924, Lab (815) 395-5907

Research Interests: Genome instability is a hallmark of cancer, and malfunctions in DNA double-strand break repair drive the large rearrangements that are seen in many cancers.  My group studies the role of DNA double-strand break repair in oncogenesis, development of DNA repair factors as targets for new cancer therapies, and the potential for use of DNA repair factors as predictors of therapeutic response in personalized medicine.  

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Ashley Hall, PhD, Assistant professor of Forensic Science

amhall7@uic.edu, Office (312) 996-2560

Research Interests: Forensic DNA analysis and body fluid identification.  My research focuses on the development of techniques for the analysis of challenging forensic samples.  Current projects include an optimization of strategies for the collection and analysis of low template and damaged DNA, a comprehensive analysis of the biological components of touch DNA and the evaluation of their possible applications in forensic profiling, rapidly mutating and stable Y-chromosome markers and applications of body fluid identification.

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Hyun-Young Jeong, PhamD, PhD, Professor of Pharmacology

yjeong@uic.edu, Office (312) 996-7820, Fax (312) 996-0379,
Lab (312) 413-1771
Lab webpage 

Research Interests:  Clinical/preclinical pharmacokinetics; pharmacogenomics; eukaryotic gene regulation

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A. Karl Larsen, PhD, Clinical Professor of Forensic Science, Director of Graduate Studies (Forensic Science)

larsena@uic.edu, Office (312) 996-2250

Research Interests: Forensic Toxicology, Controlled Substances, Intoxicating Compounds

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Steve Seung-Young Lee, PhD, Assistant Professor

ssylee@uic.edu, Office (312) 413-8294; Lab (312) 355-0414

Curriculume Vitae

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John L. Nitiss, PhD, Professor of Pharmacology, Assistant Dean for Research, Rockford Campus

jlnitiss@uic.edu, Office (815) 395-5583, Lab (815) 395-5788

Research Interests: The Nitiss laboratory uses a combination of genetic and biochemical tools to understand the action of anti-cancer agents.  Our hallmark approach uses yeast as a model system to define the pathways responsible for cell killing and drug resistance by anti-cancer drugs, and to apply insights obtained with yeast to in vitro biochemical systems and to mammalian cells.  We have been particularly interested in anti-cancer drugs that target DNA topoisomerases, and how topoisomerases influence genome stability.
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Hayat Onyuksel, PhD, Professor of Pharmaceutics and Bioengineering

hayat@uic.edu, Office (312) 996-2097, Lab (312) 996-9277

Research Interests: Developing novel targeted nanomedicines for cancer, Alzheimer's, inflammatory and cardiovascular diseases. Drug delivery using nanotechnology and nanomedicine. Early detection and targeted chemotherapy of breast cancer.  Formulation and delivery of peptide and protein drugs using lipid-based carrier systems. Targeted therapy of rheumatoid arthritis. Liposomes (StealthR, targeted and conventional) as drug delivery systems, ultrasound contrast agent and model membranes. 

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R. Francis Schlemmer, PhD, Associate Professor of Pharmacodynamics

schlemm@uic.edu, Office (312) 996-9264

Research Interests: Pharmacy and Pharmacology Education. Behavioral pharmacology of psychotherapeutic drugs and drugs of abuse, development of primate models of mental disorders. 

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Donald P. Waller, PhD, Professor of Pharmacology

dpwaller@uic.edu, Office (312) 413-1841

Research Interests: Reproductive pharmacology and toxicology, STD prevention in women, environmental toxicology. Characterization of PCB exposures in pregnant African American women through ingestion of fish from Lake Michigan. Toxicology studies on new contraceptive devices and agents. Antifertility screening of plant-derived compounds and crude plant extracts. Mechanisms of male mediated effects on fetal development.

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Zaijie (Jim) Wang, PhD, Professor of Pharmacology and Pharmaceutics

Office (312) 355-1429

Lab webpage

Research Interests: Pain, addiction, and natural product pharmacology.
We apply the power of neurobiology, pharmacology, molecular biology, genetics, and targeted delivery in our studies. 

                                                                                                                                                                                                                                                                                                                                                                   

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