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Photo of Birgit M. Dietz

Birgit M. Dietz

Research Associate Professor, Medicinal Chemistry and Pharmacognosy

Contact Information

833 S. Wood Street (871)
164
Chicago, IL 60612

Phone: (312) 996-2358

Intellectual Contributions

Journal Article

  • Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen S, Nikolic DS, Pauli GF, van Breemen RB, Dietz BM, Bolton JL. "Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.". Chemical research in toxicology. 2015;28(11):2130-41. doi:10.1021/acs.chemrestox.5b00310.
  • Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen S, Nikolic DS, Pauli GF, van Breemen RB, Dietz BM, Bolton JL. "Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.". Chemical research in toxicology. 2015;28(11):2130-41. doi:10.1021/acs.chemrestox.5b00310.
  • Dunlap TL, Wang S, Simmler C, Chen S, Pauli GF, Dietz BM, Bolton JL. "Differential Effects of Glycyrrhiza Species on Genotoxic Estrogen Metabolism: Licochalcone A Downregulates P450 1B1, whereas Isoliquiritigenin Stimulates It.". Chemical research in toxicology. 2015;28(8):1584-94. doi:10.1021/acs.chemrestox.5b00157.
  • Dunlap TL, Wang S, Simmler C, Chen S, Pauli GF, Dietz BM, Bolton JL. "Differential Effects of Glycyrrhiza Species on Genotoxic Estrogen Metabolism: Licochalcone A Downregulates P450 1B1, whereas Isoliquiritigenin Stimulates It.". Chemical research in toxicology. 2015;28(8):1584-94. doi:10.1021/acs.chemrestox.5b00157.
  • van Breemen RB, Yuan Y, Banuvar S, Shulman LP, Qiu X, Alvarenga RF, Chen S, Dietz BM, Bolton JL, Pauli GF, Krause EC, Viana M, Nikolic DS. "Pharmacokinetics of prenylated hop phenols in women following oral administration of a standardized extract of hops.". Molecular nutrition & food research. 2014;58(10):1962-9. doi:10.1002/mnfr.201400245.
  • Krause EC, Yuan Y, Hajirahimkhan A, Dong H, Dietz BM, Nikolic DS, Pauli GF, Bolton JL, van Breemen RB. "Biological and chemical standardization of a hop (Humulus lupulus) botanical dietary supplement.". Biomedical chromatography : BMC. 2014;28(6):729-34. doi:10.1002/bmc.3177.
  • Hajirahimkhan A, Simmler C, Yuan Y, Anderson JR, Chen S, Nikolić D, Dietz BM, Pauli GF, van Breemen RB, Bolton JL. "Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms.". PloS one. 2013;8(7):e67947. doi:10.1371/journal.pone.0067947.
  • Hajirahimkhan A, Simmler C, Yuan Y, Anderson JR, Chen S, Nikolic DS, Dietz BM, Pauli GF, van Breemen RB, Bolton JL. "Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms.". PloS one. 2013;8(7):e67947. doi:10.1371/journal.pone.0067947.
  • Dietz BM, Hagos GK, Eskra JN, Wijewickrama GT, Anderson JR, Nikolic DS, Guo J, Wright BJ, Chen S, Pauli GF, van Breemen RB, Bolton JL. "Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo.". Molecular nutrition & food research. 2013;57(6):1055-66. doi:10.1002/mnfr.201200534.
  • Hajirahimkhan A, Dietz BM, Bolton JL. "Botanical modulation of menopausal symptoms: mechanisms of action?". Planta medica. 2013;79(7):538-53. doi:10.1055/s-0032-1328187.
  • Snelten CS, Dietz BM, Bolton JL. "Modulation of Estrogen Chemical Carcinogenesis by Botanical Supplements used for Postmenopausal Women's Health.". Drug discovery today. Disease mechanisms. 2012;9(1). doi:10.1016/j.ddmec.2012.11.001.
  • Hemachandra LP, Madhubhani P, Chandrasena R, Esala P, Chen S, Main M, Lankin DC, Scism RA, Dietz BM, Pauli GF, Thatcher GR, Bolton JL. "Hops (Humulus lupulus) inhibits oxidative estrogen metabolism and estrogen-induced malignant transformation in human mammary epithelial cells (MCF-10A).". Cancer prevention research (Philadelphia, Pa.). 2012;5(1):73-81. doi:10.1158/1940-6207.CAPR-11-0348.
  • Gödecke T, Yao P, Napolitano JG, Nikolić D, Dietz BM, Bolton JL, van Breemen RB, Farnsworth NR, Chen S, Lankin DC, Pauli GF. "Integrated standardization concept for Angelica botanicals using quantitative NMR.". Fitoterapia. 2012;83(1):18-32. doi:10.1016/j.fitote.2011.08.017.
  • Dietz BM, Bolton JL. "Biological reactive intermediates (BRIs) formed from botanical dietary supplements.". Chemico-biological interactions. 2011;192(1-2):72-80. doi:10.1016/j.cbi.2010.10.007.
  • Wang Z, Wijewickrama GT, Peng KW, Dietz BM, Yuan L, van Breemen RB, Bolton JL, Thatcher GR. "Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus.". The Journal of biological chemistry. 2009;284(13):8633-42. doi:10.1074/jbc.M807860200.
  • Gödecke T, Nikolic DS, Lankin DC, Chen S, Powell SL, Dietz BM, Bolton JL, van Breemen RB, Farnsworth NR, Pauli GF. "Phytochemistry of cimicifugic acids and associated bases in Cimicifuga racemosa root extracts.". Phytochemical analysis : PCA. 2009;20(2):120-33. doi:10.1002/pca.1106.
  • Powell SL, Gödecke T, Nikolic DS, Chen S, Ahn S, Dietz BM, Farnsworth NR, van Breemen RB, Lankin DC, Pauli GF, Bolton JL. "In vitro serotonergic activity of black cohosh and identification of N(omega)-methylserotonin as a potential active constituent.". Journal of agricultural and food chemistry. 2008;56(24):11718-26. doi:10.1021/jf803298z.
  • Dietz BM, Liu D, Hagos GK, Yao P, Schinkovitz A, Pro SM, Deng S, Farnsworth NR, Pauli GF, van Breemen RB, Bolton JL. "Angelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: quinone oxidoreductase 1 by alkylating Keap1.". Chemical research in toxicology. 2008;21(10):1939-48. doi:10.1021/tx8001274.
  • Yu B, Dietz BM, Dunlap TL, Kastrati I, Lantvit DD, Overk CR, Yao P, Qin Z, Bolton JL, Thatcher GR. "Structural modulation of reactivity/activity in design of improved benzothiophene selective estrogen receptor modulators: induction of chemopreventive mechanisms.". Molecular cancer therapeutics. 2007;6(9):2418-28. doi:10.1158/1535-7163.MCT-07-0268.
  • Dietz BM, Bolton JL. "Botanical dietary supplements gone bad.". Chemical research in toxicology. 2007;20(4):586-90. doi:10.1021/tx7000527.
  • Gafner S, Dietz BM, McPhail KL, Scott IM, Glinski JA, Russell FE, McCollom MM, Budzinski JW, Foster BC, Bergeron C, Rhyu MR, Bolton JL. "Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro.". Journal of natural products. 2006;69(3):432-5. doi:10.1021/np058114h.
  • Liu G, Eggler AL, Dietz BM, Mesecar AD, Bolton JL, Pezzuto JM, van Breemen RB. "Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1.". Analytical chemistry. 2005;77(19):6407-14. doi:10.1021/ac050892r.
  • Dietz BM, Kang YH, Liu G, Eggler AL, Yao P, Chadwick LR, Pauli GF, Farnsworth NR, Mesecar AD, van Breemen RB, Bolton JL. "Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase.". Chemical research in toxicology. 2005;18(8):1296-305. doi:10.1021/tx050058x.
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