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Photo of George Edward Chlipala

George Edward Chlipala

Research Assistant Professor, Medicinal Chemistry and Pharmacognosy

Contact Information

833 S. Wood Street (781)
Chicago, IL 60612


  • PhD, Pharmacognosy, University of Illinois at Chicago, Chicago, IL, 2010
  • BS, Cum laude, Biological Research, Loras College, Dubuque, IA, 1998

Intellectual Contributions

Journal Article

  • Luo S, Krunic A, Chlipala GE, Orjala J. "Microseiramide from the Freshwater Cyanobacterium Microseira sp. UIC 10445.". Phytochemistry letters. 2015;13:47-52. doi:10.1016/j.phytol.2015.05.003.
  • Aggarwal C, Jimenez Romaguera JC, Lee H, Chlipala GE, Ratia K, Federle M. "Identification of Quorum-Sensing Inhibitors Disrupting Signaling between Rgg and Short Hydrophobic Peptides in Streptococci.". mBio. 2015;6(3):e00393-15. doi:10.1128/mBio.00393-15.
  • Tripathi A, Schofield MM, Chlipala GE, Schultz PJ, Yim I, Newmister SA, Nusca TD, Scaglione JB, Hanna PC, Tamayo-Castillo G, Sherman DH. "Baulamycins A and B, broad-spectrum antibiotics identified as inhibitors of siderophore biosynthesis in Staphylococcus aureus and Bacillus anthracis.". Journal of the American Chemical Society. 2014;136(4):1579-86. doi:10.1021/ja4115924.
  • Luo S, Kang HS, Krunic A, Chlipala GE, Cai G, Chen W, Franzblau SG, Swanson SM, Orjala J. "Carbamidocyclophanes F and G with Anti-Mycobacterium tuberculosis Activity from the Cultured Freshwater Cyanobacterium Nostoc sp.". Tetrahedron letters. 2014;55(3):686-689. doi:10.1016/j.tetlet.2013.11.112.
  • Chemler JA, Buchholz TJ, Geders TW, Akey DL, Rath CM, Chlipala GE, Smith JL, Sherman DH. "Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor.". Journal of the American Chemical Society. 2012;134(17):7359-66. doi:10.1021/ja2112228.
  • Chlipala GE, Mo S, Orjala J. "Chemodiversity in freshwater and terrestrial cyanobacteria - a source for drug discovery.". Current drug targets. 2011;12(11):1654-73.
  • Chlipala GE, Krunic A, Mo S, Sturdy M, Orjala J. "CYANOS: a data management system for natural product drug discovery efforts using cultured microorganisms.". Journal of chemical information and modeling. 2011;51(1):171-80. doi:10.1021/ci100280a.
  • Chlipala GE, Sturdy M, Krunic A, Lantvit DD, Shen Q, Porter K, Swanson SM, Orjala J. "Cylindrocyclophanes with proteasome inhibitory activity from the Cyanobacterium Nostoc sp.". Journal of natural products. 2010;73(9):1529-37. doi:10.1021/np100352e.
  • Chlipala GE, Pham HT, Nguyen VH, Krunic A, Shim SH, Soejarto DD, Orjala J. "Nhatrangins A and B, aplysiatoxin-related metabolites from the marine cyanobacterium Lyngbya majuscula from Vietnam.". Journal of natural products. 2010;73(4):784-7. doi:10.1021/np100002q.