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Photo of Jinhong Ren

Jinhong Ren

Visiting Research Specialist, Center for Biomolecular Sciences

Contact Information

900 S. Ashland Avenue (870)
MBRB Rm 1052
Chicago, IL 60607

Phone: (312) 413-9304

Education

  • PhD, Medicinal Chemistry, Shenyang Pharmaceutical University, Shenyang, China, 2009
  • BS, Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, China, 2004

Research Interests

Molecular Modeling for Antibacterial and Antiviral Active compounds

Intellectual Contributions

Journal Article

  • Zhao N, Ren X, Ren J, Lü H, Ma S, Gao R, Li Y, Xu S, Li L, Yu S. "Total Syntheses of (-)-Spirooliganones A and B and Their Diastereoisomers: Absolute Stereochemistry and Inhibitory Activity against Coxsackie Virus B3.". Organic letters. 2015;17(12):3118-21. doi:10.1021/acs.orglett.5b01419.
  • Zhao D, Sun B, Ren J, Li F, Song S, Lv X, Hao C, Cheng M. "Synthesis and biological evaluation of 3-phenyl-3-aryl carboxamido propanoic acid derivatives as small molecule inhibitors of retinoic acid 4-hydroxylase (CYP26A1).". Bioorganic & medicinal chemistry. 2015;23(6):1356-65. doi:10.1016/j.bmc.2014.11.036.
  • Mei M, Zhang Y, Ren J, Xie D, Jia YF, Hu JP, Li Y, Dai JG, Chen XG. "[Resistance reversal effect of a novel taxane compound NPB304 and its collaboration with verapamil].". Yao xue xue bao = Acta pharmaceutica Sinica. 2014;49(9):1279-88.
  • Li F, Zhao D, Ren J, Hao F, Liu G, Jin S, Jing Y, Cheng M. "2-(2-Methylfuran-3-carboxamido)-3-phenylpropanoic acid, a potential CYP26A1 inhibitor to enhance all-trans retinoic acid-induced leukemia cell differentiation based on virtual screening and biological evaluation.". Bioorganic & medicinal chemistry. 2013;21(11):3256-61. doi:10.1016/j.bmc.2013.03.044.
  • Du D, Yan J, Ren J, Lv H, Li Y, Xu S, Wang Y, Ma S, Qu J, Tang W, Hu Z, Yu S. "Synthesis, biological evaluation, and molecular modeling of glycyrrhizin derivatives as potent high-mobility group box-1 inhibitors with anti-heart-failure activity in vivo.". Journal of medicinal chemistry. 2013;56(1):97-108. doi:10.1021/jm301248y.
  • Bai J, Fang ZF, Chen H, Yu SS, Zhang D, Wei HL, Ma SG, Li Y, Qu J, Xu S, Ren J, Zhao F, Zhao N, Liu JH. "Antioxidant phenolic glycosides from the roots of Illicium dunnianum.". Carbohydrate research. 2012;361:206-11. doi:10.1016/j.carres.2012.08.017.
  • Yu P, Lv H, Li C, Ren J, Ma S, Xu S, Chen X, Yu S, . "Stereospecific Synthesis and Biological Evaluation of Monodesmethyl Metabolites of (+)-13a-(S)-Deoxytylophorinine as Potential Antitumor Agents. ". . 44(24):3757-3764. doi:DOI: 10.1055/s-0032-1316810.
  • Bai J, Chen H, Fang ZF, Yu SS, Ma SG, Li Y, Qu J, Xu S, Ren J, Lü HN, Chen X. "Sesquiterpenes and neolignans from the roots of Illicium dunnianum.". Journal of Asian natural products research. 2012;14(10):940-9. doi:10.1080/10286020.2012.729507.
  • Lv H, Ren J, Ma S, Xu S, Qu J, Liu Z, Zhou Q, Chen X, Yu S. "Synthesis, biological evaluation and mechanism studies of deoxytylophorinine and its derivatives as potential anticancer agents.". PloS one. 2012;7(1):e30342. doi:10.1371/journal.pone.0030342.
  • Chen H, Bai J, Fang ZF, Yu SS, Ma SG, Xu S, Li Y, Qu J, Ren J, Li L, Si YK, Chen XG. "Indole alkaloids and quassinoids from the stems of Brucea mollis.". Journal of natural products. 2011;74(11):2438-45. doi:10.1021/np200712y.
  • Ma SG, Tang WZ, Yu SS, Chen XG, Liu Y, Wang WJ, Qu J, Xu S, Ren J, Li Y, Lü HN. "Four new phenolic diglycosides from the roots of Illicium oligandrum.". Carbohydrate research. 2011;346(9):1165-8. doi:10.1016/j.carres.2011.03.021.
  • Ma SG, Tang WZ, Liu Y, Hu YC, Yu SS, Zhang Y, Chen XG, Qu J, Ren J, Liu Y, Xu S, Liu J, Liu Y, Li Y, Lü HN, Wu XF. "Prenylated C6-C3 compounds with molecular diversity from the roots of Illicium oligandrum.". Phytochemistry. 2011;72(1):115-25. doi:10.1016/j.phytochem.2010.10.021.
  • Xiong XQ, Zhao DM, Bu PF, Liu Y, Ren J, Wang J, Cheng MS. "CoMFA, CoMSIA and eigenvalue analysis on dibenzodioxepinone and dibenzodioxocinone derivatives as cholesteryl ester transfer protein inhibitors.". Molecules (Basel, Switzerland). 2008;13(8):1822-39.
  • Ren J, Xiong X, Yu S, Yan M, Lin B, Wang J, Jing Y, Zhao D, Cheng M. "Structure prediction and R115866 binding study of human CYP26A1: homology modelling, fold recognition, molecular docking and MD simulations. ". Molecular Simulation. 2008;34:337-346. doi:10.1080/08927020801930562.
  • Yan MC, Sha Y, Wang J, Xiong XQ, Ren J, Cheng MS. "Molecular dynamics simulations of HIV-1 protease monomer: Assembly of N-terminus and C-terminus into beta-sheet in water solution.". Proteins. 2008;70(3):731-8. doi:10.1002/prot.21539.
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