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Photo of Jimmy Orjala

Jimmy Orjala

Associate Professor of Pharmacognosy, Medicinal Chemistry and Pharmacognosy

Contact Information

900 S Ashland Avenue
3170 MBRB
Chicago, IL 60607

Phone: (312) 996-5583

Intellectual Contributions

Journal Article

  • Krunic A, Orjala J. "Application of high-field NMR spectroscopy for characterization and quantitation of submilligram quantities of isolated natural products.". Magnetic resonance in chemistry : MRC. 2015;53(12):1043-50. doi:10.1002/mrc.4304.
  • Luo S, Krunic A, Chlipala GE, Orjala J. "Microseiramide from the Freshwater Cyanobacterium Microseira sp. UIC 10445.". Phytochemistry letters. 2015;13:47-52. doi:10.1016/j.phytol.2015.05.003.
  • Luo S, Kang HS, Krunic A, Chen W, Yang J, Woodard JL, Fuchs JR, Hyun Cho S, Franzblau SG, Swanson SM, Orjala J. "Trichormamides C and D, antiproliferative cyclic lipopeptides from the cultured freshwater cyanobacterium cf. Oscillatoria sp. UIC 10045.". Bioorganic & medicinal chemistry. 2015;23(13):3153-62. doi:10.1016/j.bmc.2015.04.073.
  • Luo S, Kang HS, Krunic A, Chlipala GE, Cai G, Chen W, Franzblau SG, Swanson SM, Orjala J. "Carbamidocyclophanes F and G with Anti-Mycobacterium tuberculosis Activity from the Cultured Freshwater Cyanobacterium Nostoc sp.". Tetrahedron letters. 2014;55(3):686-689. doi:10.1016/j.tetlet.2013.11.112.
  • Kim H, Lantvit DD, Hwang CH, Kroll DJ, Swanson SM, Franzblau SG, Orjala J. "Indole alkaloids from two cultured cyanobacteria, Westiellopsis sp. and Fischerella muscicola.". Bioorganic & medicinal chemistry. 2012;20(17):5290-5. doi:10.1016/j.bmc.2012.06.030.
  • Kang HS, Santarsiero BD, Kim H, Krunic A, Shen Q, Swanson SM, Chai H, Kinghorn AD, Orjala J. "Merocyclophanes A and B, antiproliferative cyclophanes from the cultured terrestrial Cyanobacterium Nostoc sp.". Phytochemistry. 2012;79:109-15. doi:10.1016/j.phytochem.2012.03.005.
  • Chlipala GE, Mo S, Orjala J. "Chemodiversity in freshwater and terrestrial cyanobacteria - a source for drug discovery.". Current drug targets. 2011;12(11):1654-73.
  • Chlipala GE, Krunic A, Mo S, Sturdy M, Orjala J. "CYANOS: a data management system for natural product drug discovery efforts using cultured microorganisms.". Journal of chemical information and modeling. 2011;51(1):171-80. doi:10.1021/ci100280a.
  • Mo S, Krunic A, Santarsiero BD, Franzblau SG, Orjala J. "Hapalindole-related alkaloids from the cultured cyanobacterium Fischerella ambigua.". Phytochemistry. 2010;71(17-18):2116-23. doi:10.1016/j.phytochem.2010.09.004.
  • Mo S, Krunic A, Santarsiero BD, Franzblau SG, Orjala J. "Hapalindole-related alkaloids from the cultured cyanobacterium Fischerella ambigua.". Phytochemistry. 2010;71(17-18):2116-23. doi:10.1016/j.phytochem.2010.09.004.
  • Chlipala GE, Sturdy M, Krunic A, Lantvit DD, Shen Q, Porter K, Swanson SM, Orjala J. "Cylindrocyclophanes with proteasome inhibitory activity from the Cyanobacterium Nostoc sp.". Journal of natural products. 2010;73(9):1529-37. doi:10.1021/np100352e.
  • Chlipala GE, Pham HT, Nguyen VH, Krunic A, Shim SH, Soejarto DD, Orjala J. "Nhatrangins A and B, aplysiatoxin-related metabolites from the marine cyanobacterium Lyngbya majuscula from Vietnam.". Journal of natural products. 2010;73(4):784-7. doi:10.1021/np100002q.
  • Mo S, Krunic A, Pegan SD, Franzblau SG, Orjala J. "An antimicrobial guanidine-bearing sesterterpene from the cultured cyanobacterium Scytonema sp.". Journal of natural products. 2009;72(11):2043-5. doi:10.1021/np900288x.
  • Guo S, Tipparaju SK, Pegan SD, Wan B, Mo S, Orjala J, Mesecar AD, Franzblau SG, Kozikowski AP. "Natural product leads for drug discovery: isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3-a]carbazole based ligands as antibacterial agents.". Bioorganic & medicinal chemistry. 2009;17(20):7126-30. doi:10.1016/j.bmc.2009.08.061.
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