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Congratulations to our researchers!
Jeremy Johnson and co-Is Maarten Bosland (Pathology), Chun-Tao Che, Ravinder Gill (Gastroenterology and Hepatology), and Sekhar Reddy (Pediatrics) received $470,000 for their project "Rosemary as a Food Preservative: Implications for Gastrointestinal Health".
Farahnaz Movahed Zadeh and Shahila Mehboob received $600 from the SENCER Center for Innovation – Midwest via the NSF for her project "Introduction to Biological Research: A one-day workshop for students interested in pursuing advanced scientific degrees”."
Stephen DiMagno received $47,805 as an R21 subaward from the NIH/NCI for his project "Radiolabeled FASN inhibitors for PET Imaging".
Terry Moore and co-Is Luisa DiPietro (Periodontics), Seungpyo Hong (U Wisconsin), and Sekhar Reddy (Pediatrics) received $1,042,272 from the NIH/NIAMS for his project "Non-Covalent Nrf2 Activators for the Treatment of Chronic Wounds".
Joanna Burdette received $399,750 from the DoD for her project "Pax8: A unifying target for serous tumors".
Michael Johnson received $159,867 as a R33 subaward from the NIH for his project "Antibiotic Potentiation by Targeting of a Signal Transduction System".
Daniel Touchette and co-Is Todd Lee, Simon Pickard, Glen Schumock, and Surrey Walton received funding from the Institute for Clinical Research for the project "Institute for Clinical and Economic Review Consulting Agreement".
Alexandria Young (Burdette lab) received a Ruth L. Kirschstein National Research Service Award (NRSA) Fellowship for MD/PhD students from the NIH for $217.880 for her project "FemKube, the Human Female Reproductive Tract-on-a-chip, as a Platform for Studying High Grade Serous Ovarian Cancer and Developing Novel Cancer Chemotherapeutics"
Yeuting Wang (UICentre), PI Leon Tai (Anatomy and Cell Biology), and co-Is Irina Gaisina (UICentre) and Kejia Cai (Radiology) received $439.725 from the NIH/NIA for their project "Targeting APOE Modulated Neurovascular Dysfunction".
Artemis Gogos (Federle lab) received a Foundation Seed Grant for $1973 from the American Medical Association (AMA) for her project "Exploring the Role of a S. Pyogenes Quorum Sensing System on Adherence and Invasion of Tonsillar Epithelial Cells".
Simon Pickard received $294,645 from the EuroQol group for his project "US Valuation Study of the EQ-5D-5L".
Joanna Burdette received $20,000 from the TEAL (Tell Every Amazing Lady About Ovarian Cancer) Foundation for her project "Identifying the Markers of Cancer Initiation and Progression that are Altered Upon Loss of PTEN in FTE".
Yang Liu (Pauli lab) received $25,000 as a Global Fellow from the U.S Pharmacopeial Convention (USP) to support his research on "Development of Electronic Reference Standards for Mass Balance Analysis of Dietary Supplements".
Dima Qato was awarded $70,000 from Blue Cross & Blue Shield of Illinois for her project "Pharmacy Deserts and its Impact on Access to Care".
Yeuting Wang and co-Is Greg Thatcher and Mary Ladu (Anatomy and Cell Biology) received $152,003 for an R42 STTR grant from NIH for their project "Nomethiazoles harnessing GABA and NO Mimetic Activity for Alzheimer's Therapy".
Edith Nutescu is Consortium Co-Investigator and UIC site PI on a 5 year $9.5 million U54 grant from NIH/NIHMD for the project "African American Cardiovascular Pharmacogenetic Consortium (Account): Discovery and Translation". The UIC component of the grant is funded $705,105 and headed by consortium investigator Minoli Perera (Northwestern University).
Joanna Burdette received $18,000 as a subcontract PI on an R15 grant from the NIH/NIGMS for the project "Asymmetric synthesis of highly functionalized lactones and lactams using a chiral Bronsted acid". She is collaborating with Kimberly Petersen from UNC Greensboro.
Scott Franzblau, along with co-Is Celerino Abad-Zapatero (CBS), Farahnaz Movahed Zadeh (ITR), and Nina Wolf (ITR), received $20,000 from an HTS award from the Chicago Biomedical Consortium (CBC) for their project "High-Throughput Screening and Validation of Inhibitors Against M. Tuberculosis Class II FBPase."
Scott Franzblau also received $109,324 with Co-I Hyunyoung Jeong as a subcontract on an R01 grant from the NIH/NIAID for their project "Design, Syntheses and Studies of Novel Antituberculosis Agents."
Michael Federle and co-I Jennifer Chang (CBS) received $1,998,750 for a 5 year R01 grant from the NIH/NIAID for their project "Mechanisms of Pheromone-Controlled Lysozyme Resistance and Surface Display of Streptococcus Pyogenes."
Mary Moody received $40,000 in funding from the Illinois Department of Human Services for her project "FY17 BPCSS - Updating Drug Interaction System".
Richard Gemeinhart and co-Is Seungpyo Hong and Timothy Koh (Kinesiology & Nutrition) recevied $439,725 in funding from the NIH/NIBIB for their project "Activation of Monocytes and Macrophages by Polymeric Micelles".
Lisa Sharp, along with PI Sharmilee Nyenhuis (College of Medicine) and co-I David Marquez (Kinesiology & Nutrition), received $740,620 in funding from the NIH/NHLBI for their project "ACTION Intervention: Physical Activity in Minority Women with Asthma".
Surrey Walton, along with PI Naoko Muramatsu (Institute for Health Research & Policy) and Co-Is David Marquez (Kinesiology & Nutrition) and Michael Berbaum (Institute for Health Research & Policy), received an R01 for $3 million from the NIH/NIA for their project "Promoting Seniors' Health with Home Care Aides: A Randomized Controlled Trial".
Todd Lee and Lisa Sharp, as co-Is with Min Joo of the College of Medicine, received an R01 for $1.5 million from AHRQ for their project "Reducing Diagnostic Error to Improve Patient Safety in COPD and Asthma (REDEFINE Study)".
Joanna Burdette received $359,492 from the NIH/NCI for her project "Pax2 Loss in Fallopian Tube Lesions and Strategies for Restoration in Serous Cancer".
Co-PIs Alexander Mankin and Nora Vazquez-Laslop received $1,000,000 in total direct costs for a 4 year grant from the NIH to fund their project "Context-Specific Action of Antibiotics Targeting the Catalytic Center of the Bacterial Ribosome".
Lisa Sharp, co-PI Ben Gerber from the UIC College of Medicine, and co-investigator Jessica Tilton have been awarded $3.4 million for a 5 year R01 grant from the NIH/NIDDK for their project "mHealth for Diabetes Adherence Support".
Michael Federle received $600,000 in total direct costs for a 4 year R01 grant from the NIH, in collaboration with Matthew Neiditch from Rutgers University, for their project "Molecular Mechanisms of Regg Receptor Regulation by Pheromones and Inhibitors."
Michael Johnson received $20,000 from the Chicago Biomedical Consortium for his project "Identification and Development of Small Molecules that Inhibit the VraSRT Operon, Which Maintains Oxacillin Resistance in Methicillin-Resistant S. Aureus (MRSA)".
Miaoran Ning (Jeong lab) received $10,000 as a graduate fellowship from the American Association of Pharmaceutical Scientists to support her research on "Molecular Basis of Inter-individual Variability in CYP2D6-Mediated Drug Metabolism".
Jason Bugno (Hong lab) received $10,000 as a graduate fellowship from the American Association of Pharmaceutical Scientists to support his research on "The Use of Hybrid Dendritic-Linear Polymeric Nanoparticles for Tumor-Specific Accumulation with Tailored Tissue Permeation".
Hyunyoung Jeong and her University of Chicago collaborator, Eugene Chang, received $199,998 for the Chicago Biomedical Consortium Catalyst Award "Role of Gut Microbiota in Determining Drug Efficacy and Toxicity".
Michael Johnson received $159,867 from NIH/NIAID as a subcontract PI on R33 grant "Antibiotic Potentiation by Targeting of a Signal Transduction System". He is colaborating with University of Chicago group lead by Robert Daum and Susan Boyle-Vavra.
Alan Kozikowski received $384,147 in continuation funding from the NIH/NINDS for R01 grant “Optimization of HDAC6 Inhibitors in the Treatment of CMT”.
Jim Wang and his Co-PI Frank Porreca (University of Arizona) received $567,508 for the first year of their NIH/NIDA R01 grant "Cortical Opioid Dysfunction in Chronic Pain".
Keith Rodvold received funding from Theravance Biopharma Antibiotics, Inc., for project "Pharmacokinetics of Telavancin in Normal and Obese Subjects".
Jim Wang received $404,011 from NIH/NHLBI for new R01 grant "Protein Kinase Mechanisms for Chronic Pain in Sickle Cell Disease".
Hyunyoung Jeong received $39,950 from Indiana University for NIH/NIAID R21 project "Development of Anti-Virulence Drugs by Targeting the SaeRS Two Component System of Staphylococcus aureus".
Richard van Breemen received $550,960 for the fourth year of the NIH/NCCIH T32 training grant "Research Training in Natural Product Complementary and Alternative Medicine".
Binh Chu (Murphy lab) received postdoctoral research grant from the Chicago Biomedical Consortium for project "Droplet Digital PCR to Assess the Abundance of Antibiotic Resistance Genes in Lake Michigan."
Edith Nutescu received an award from the American Society of Health-System Pharmacists (ASHP) Research and Education Foundation for her project "Novel Pharmacist Led Personalized Medicine Program Improves Patient Safety, Clinical and Health-Care Utilization Outcomes".
Seungpyo Hong received $112,804 as a subcontract investigator on NIH/NCI funded R01 grant "Potential Therapeutic Implications of Targeting miR-150 In Acute Myeloid Leukemia". He is collaborating with Jianjun Chen of University of Cincinnati.
James Fischer received $344,034 for Chicago Area Patient Centered Outcomes Research Network (CAPriCORN), initiative funded by Patient-Centered Outcome Research (PCORI) via Chicago Community Trust.
Todd Lee received $19,989 from NIH/NHLBI via University of Arizona for project "The Cost Effectiveness of School-Based Supervised Asthma Therapy".
Edith Nutescu received $132,095 in continuation funding from the NIH/NHLBI for K23 grant “Anticoagulation Self-Monitoring in Minority Patients.”
Dima Qato received $193,966 in continuation funding from the NIH/NIA for R21 grant “Pharmacy Accessibility and Disparities in Adherence to Cardiovascular Medications in the Elderly.”
Laura Cook (Federle lab) received $56,118 to continue her NIH/NIAID-funded F32 project "Determining the role of dialog between pathogenic Streptococci in biofilm development and virulence".
Michael Rush (van Breemen lab) received $43,120 in new funding for his NIH/NCCIH F31 predoctoral fellowship project "Discovery of Natural Product Inhibitors of Fuctose-1, 6-Bisphophatase for the Obesity Management".
Keith Rodvold received $601,065 as a subcontract PI on NIH/NIAID cooperative agreement "Antibacterial Resistance Leadership Group (ARLG)". He is working with the Duke University.
Joanna Burdette received $20,000 from ®Tell Every Amazing Lady (T.E.A.L) About Ovarian Cancer Louisa M. McGregor Ovarian Cancer Foundation for project "Prevention of Ovarian Cancer by Pax2".
Joanna Burdette received $148, 262 as a subcontract PI on NIH/NIBIB-funded project "Steriod-Based Contrast Agents for Magnetic Resonance Imaging of Endocrine Disease".
Daniel Touchette received $167,636 in new funding from Cardinal Health for project "Evaluation of a Novel Medication Use Health and Wellness Solution in Patients with Diabetes". He is collaborating with Co-PI Lisa Sharp and Co-I Kellyn Moran.
Surrey Walton received $13,593 as a subcontract PI on NIH/NIDDKD funded R01 grant "Testing a Medication Risk Communication and Surveillance Strategy: The Emc2 Trial".
Hyunyoung Jeong received $111,929 in continuation funding as a subcontract PI on NIH/NIGMS funded R37 grant "Design & Synthesis of Nonpeptide Protease Inhibitors".
Gregory Thatcher and Pavel Petukhov received $733,700 in continuation funds as Co-PIs on NIH/NHLBI funded CADET grant "Therapeutic Targeting of Carotid Body Chemoreflex for Sleep-Disordered Breathing". They are collaborating with Co-Investigators Jimmy Orjala and Terry Moore.
Laura Sanchez has been named Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) Scholar.
Keith Rodvold received $21,474 in supplemental funding as a subcontract PI on NIH/NIAID research project cooperative agreement "ARLG: Leadership Group for a Clinical Research Network on Antibacterial Resistance".
Alan Kozikowski received $118,893 as a subcontract PI on NIH/NCI R01 grant "RAD51 Inhibitors for Chemotherapy and Radiation Therapy". He is collaborating with University of Chicago's Phil Connell.
Hyunyoung Jeong received $7,246 in continuation finding as a subcontract PI on NIH/NIMHHD R01 grant with U. of Chicago Minoli Perera entitled "Health Disparity in Pharmacogenomics: African American SNPs and Drug Metabolism".
Karol Bruzik received $229,818 in continuation funding as a UIC co-investigator on NIH/NIGMS P01 project "General Anesthetic Sites on Ligand-Gated Ion Channels" awarded to Massachusetts General Hospital.
Guido Pauli received $260,000 in new funds from NIH/NCCIH to establish "UIC Natural Products Technology Center" that will serve as a national resource and provide leadership for the advancement of innovative technologies and methods used in natural products research.
Joanna Burdette received $48,482 from Northwestern University as a subcontract PI on NIH/NCATS funded cooperative agreement "Ex Vivo Female Reproductive Tract Integration in a 3D Microphysiologic System ".
Co-PIs Alexander Mankin and Nora Vazquez-Laslop received $303,050 in continuation funding from the NIH/NIGMS for R01 grant “Programmed Translation Arrest Controlled by Nascent Peptides and Antibiotics.”
Two graduate students are this year's recipients of the pre-doctoral fellowship from the American Foundation for Pharmaceutical Education (AFPE). Jason Bugno (Seungpyo Hong lab) received $10,000 to support his study on "The use of hybrid dendritic-linear polymeric nanoparticles for tumor-specific accumulation with tailored tissue permeation". Michael Mullowney (Brian Murphy lab) received $10,000 to work on "Antibiotics from marine- and freshwater-derived actinomycete bacteria that inhibit drug-resistant M. tuberculosis".
Thomas Speltz and his mentor, Terry Moore received the 2015 AACP Walmart Scholar travel award. The 2015 AACP Walmart Scholars Program provided $1,000 scholarships to up to 85 student-faculty pairs to attend the 2015 AACP Annual Meeting and Teachers Seminar in National Harbor, Maryland from July 11-15.
Laura Gauthier (Guido Pauli lab) received $48,048 in new funding for her NIH F31 fellowship. Her project, "Metabolomic Botanical Standardization for Pharmacokinetic Interactions" is funded by National Center for Complementary & Integrative Health (NCCIH).
Karol Bruzik received $37,323 in continuation funding as a co-investigator on NIH/NIGMS R01 project "General Anesthetic Sites in GABA-A Receptor Subunit Interfacial Pockets".
Hyunwoo Lee received $398,750 continuation funding for NIH/NIAID R01 grant "Peptide Based Quorum Sensing Controlling Virulence in Bacillus anthracis".
Gregory Thatcher received $235,231 in continuation funds for NIH/NCI R01 grant "Biointeractions of Antiestrogens with Nitric Oxide".
Les Hanakahi and UIC collaborator John Nitiss received $196,828 in continuation funds for NIH/NCI R21 grant "Regulation of Non-Homologous End Joining through End Processing."
Erin Beisner Shanker, MD/PhD student (Mike Federle lab), received $48,200 to continue NIH/NIAID-funded F30 project "Identifying Patterns of Specificity and Promiscuity in the ComRS of Intercellular Signaling".
Jinhong Ren (Michael Johnson lab) received continuation funding from Novalex, $90,118 each, for two projects: "Development of Broad Spectrum Hepatitis C Virus NS3/4A Protease Inhibitors" and "Development of Novel S. Aureus Antibiotics with Reduced Resistance Susceptibility".
Terry Moore and UIC collaborator Sekhar Reddy received $35,000 in new funding from the UIC Chancellor’s Discovery Fund for Multidisciplinary Pilot Research for project "Development of Nrf2 Activators for the Treatment of Idiopathic Pulmonary Fibrosis".
Temitope Lawal (Gail Mahady lab) received $46,000 in new funding from Schlumberger Foundation program Faculty for the Future. She will study "Analytical Chemistry and Systems Biology of Ganoderma in Cancer Cells".
Hyunyoung Jeong received $299,992 in new funding for her NIH/NIGMS R01 grant "Molecular Basis of Interindividual Variability in CYP2D6-Mediated Drug Metabolism". She is collaborating with UIC co-investigators Julio Duarte and Leah Rubin.
Richard van Breemen received $265,020 in continuation funding from the NIH/NCCIH for R01 grant “Rapid Identification of Active Agents and Metabolomics of Botanical Supplements.”
Michael Federle received $392,500 in continuation funding for NIH/NIAID R01 grant "Mechanistic Dissection of Pheromone-Dependent Regulation of Group A Streptococcal Virulence".
Pavel Petukhov received $197,602 in continuation funding for his NIH/NIAID R21 grant "Discovery of Novel Anti-HBV Compounds Targeting Host Factors".
Edith Nutescu received support from Roche Diagnostics for her project Patient Centered Anticoagulation Self-Monitoring in Minority Patients. Roche will also provide free-of-charge materials for the study.
Michael Johnson received $104,468 in funding as a subcontract PI on NIH/NIAID R21 grant "Antibiotic Potentiation by Targeting of a Signal Transduction System" (University of Chicago).
Simon Pickard received $137,013 from Pew Charitable Trust for project "National Assessment of State Oversight of Drug Compounding".
Jinhong Ren (Michael Johnson lab) received funding from Novalex, $90,118 each, for two projects: "Development of Broad Spectrum Hepatitis C Virus NS3/4A Protease Inhibitors" and "Development of Novel S. Aureus Antibiotics with Reduced Resistance Susceptibility".
Gregory Thatcher and his UIC co-investigators Debra Tonetti and Terry Moore obtained $485,489 in NIH/NCI funding for the first year of R01 project "Partial Agonists at Estrogen Receptor a for Breast Cancer Therapy".
Jordan Gunn (Chun-Tao Che lab) received continuation funding of $42,676 for his NIH/NCCIH funded F31 grant "The Biology and Chemistry of Traditionally Used Anti-Diabetic Botanical Drugs".
Alan Kozikowski received $670,441 in continuation funding from NIH/NIMH for R01 project "Optimizing Lead 5-HT2c Ligands For Use In the Treatment of Schizophrenia".
Pavel Petukhov received $233,570 for the second year of his NIH/NCI R21 grant "Photoreactive Histone Deacetylase Probes for Chromatin Immunoprecipitation in Cancer".
Gail Mahady received $243,105 in new funding from the NIH/NCCIH for R21 grant “Osteogenic Effects of Dietary Anthocyanins in Transgenic Medaka.”
Brian Murphy and UIC collaborator Rachel Poretsky received $128,800 in new funding from the Chicago Biomedical Consortium for Catalyst Award titled “Co-Occurrence and Implications of Antibiotic Production and Resistance Genes in the Environment.”
Terry Moore and UIC collaborator Jonna Frasor received $133,330 in new funding from the Chicago Biomedical Consortium for Catalyst Award entitled "Photoaffinity-Based Protein Profiling Approach to Discover Estrogen Receptor/Coactivator Inhibitors".
Hyunyoung Jeong received $346,361 in continuation funding from the NIH/NICHD for R01 grant “Altered Drug Metabolism in Pregnancy.”
Alan Kozikowski received $377,734 in continuation funding from the NIH/NINDS for R01 grant “Optimization of HDAC6 Inhibitors in the Treatment of CMT”.
Keith Rodvold, collaborating with Vance Fowler at Duke University, received $40,384 in continuation subcontract funding from the NIH/NIAID for the UM1 grant “ARLG: Leadership Group for a Clinical Research Network on Antibacterial Resistance.”
Gregory Thatcher received $189,324 in continuation funding from the NIH/NIA for R21 grant “Potential ApoE Isoform-Specific Detrimental Effects of RXR Agonists in Alzheimer’s Therapy Studied in a Mouse Model.”
Julio Duarte received $176,964 for his K23 award from NIH/NIGMS for project "Improving Treatment Personalization for Pulmonary Hypertension Associated with Diastolic Heart Failure".
Dima Qato received $248,719 in new funding from the NIH/NIA for R21 grant “Pharmacy Accessibility and Disparities in Adherence to Cardiovascular Medications in the Elderly.”
Surrey Walton received $30,579 subcontract from Northwestern University for NIH funded project "Testing a Medication Risk Communication and Surveillance Strategy: the EMC2 Trail".
Richard van Breemen received $541,408 in continuation funding from the NIH/NCCIH for T32 institutional training grant “Research Training in Natural Products Complementary and Alternative Medicine.”
Edith Nutescu received $132,095 in continuation funding from the NIH/NHLBI for K23 grant “Anticoagulation Self-Monitoring in Minority Patients.”
Glen Schumock and A. Simon Pickard and the College have been chosen as recipients of a 2015 “Center of Excellence for Comparative Effectiveness Research (CER) Educational Program” and received $250,032 from the Pharmaceutical Research and Manufacturers of America Foundation (PhRMA).
The College received $27,000 in new funding from the American Society for Pharmacology & Experimental Therapeutics (ASPET) for program “College of Pharmacy Summer Undergraduate Research Fellowships (SURF).” The SURF program is directed by Joanna Burdette and Z. Jim Wang.
Laura Cook (Federle lab) received $13,536 Postdoctoral Research Award from the Chicago Biomedical Consortium (CBC) for her project "RNASeq analysis of the transcriptome of streptococci colonizing the vaginal tract".