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2017 FAQ's

The monthly frequently asked questions are compiled by DIG faculty, residents, and students.  These summaries provide a concise overview of a current drug therapy topic.

2017 FAQs


What information has been yielded from the cardiovascular safety studies on new anti-hyperglycemic agents?

Should tranexamic acid be added to the standard of care in treating postpartum hemorrhage?

What evidence is available on adult dosing of vancomycin in obesity?


What is the evidence for decolonization with an alcohol-based nasal antiseptic?

What evidence supports combining insulin and other antidiabetic medications in adults with type 1 diabetes?

What is the appropriate management of rabies exposure?


What is the appropriate management of hemorrhagic cystitis?

How can sodium acetate be used as a substitute for sodium bicarbonate, and what other strategies are recommended for sodium bicarbonate shortage management?

What are cardioplegia solutions?


How is acute kidney injury defined in pediatric patients?

What data are available on use of N-acetylcysteine in the management of non-acetaminophen drug-induced liver injury?

What are the new data regarding risk of sudden death in heart failure?


What is the role of minocycline in the treatment of multidrug resistant organisms?

​What evidence supports the use of coenzyme Q10 supplementation to prevent or treat statin-associated myopathy?

What evidence is available on the use of intravenous sildenafil for pulmonary arterial hypertension?


Is pregabalin effective for the treatment of sciatica pain?

What evidence is available to support the use of anti-factor Xa levels instead of activated partial thromboplastin time for monitoring of intravenous unfractionated heparin therapy in adults?

Are there any new safety concerns with antibiotics in pregnancy?


Can olanzapine be administered intravenously for the management of acute agitation?

What evidence supports the use of intravenous sub-dissociative-dose ketamine for pain in the emergency department?

What is the available evidence for the use of alteplase for occlusion of peritoneal dialysis catheters?


What is the role of bezlotoxumab in treating Clostridium difficile infections?

What is the evidence for use of high-dose vitamin C in critically ill patients?

How does brivaracetam compare to other antiepileptic agents in treating refractory partial onset seizures (POS)?


What evidence is available for the use of aprepitant (Emend) compared to other antiemetics for the prevention of postoperative nausea and vomiting?

What handling precautions should be taken when preparing monoclonal antibody drugs?

What are the American Heart Association’s recommendations for managing NOACs in acute care and peri-procedurally?


What evidence evaluates the use of procalcitonin to guide antibiotic duration in patients with hospital-acquired or ventilator-associated pneumonia?

What is the usual clinical presentation, diagnosis, and management of norovirus infection?

Which is the best method for administration of pancreatic enzyme replacement products by enteral feeding tube?


Can direct oral ant​icoagulants be prescribed to patients taking carbamazepine?

Are there data to support the treatment of Pseudomonas infections with cefepime 1 gram every 6 hours vs. 2 grams every 8 hours?

What are the treatment options for post-operative shivering?


What are the updated recommendations for the role of PCSK9 inhibitors in the management of hypercholesterolemia?

What literature supports the use of liposomal bupivacaine in transversus abdominis plane nerve blocks?

What evidence is available for using direct oral anticoagulants in HIT?