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Photo of Joanna E Burdette

Joanna E Burdette

Professor, Medicinal Chemistry and Pharmacognosy

Center Affiliate, Center for Biomolecular Sciences

Contact Information

900 S. Ashland Ave
3202 MBRB
Chicago, IL 60607

Phone: (312) 996-6153

Fax: (312) 996-7107

Website: http://joannab.people.uic.edu/

Lab Phone: (312) 996-0073

Lab Positions Available: http://joannab.people.uic.edu/

Education

  • PhD, Medicinal Chemistry and Pharmacognosy , University of Illinois at Chicago, 2003
  • BS, Emory University, Atlanta, GA, 1999

Research Lab Summary

The Burdette lab is interested in biological questions that are important for women’s health. We integrate imaging, drug discovery, and basic biology to try and understand how and where ovarian cancers originate. Our research primarily uses mouse models to understand early events in ovarian cancers. We are also using natural products to uncover new anti-cancer molecules.

Research Interests

The Burdette lab is interested in biological questions that are important for women’s health. We integrate imaging, drug discovery, and basic biology to try and understand how and where ovarian cancers originate. Our research primarily uses mouse models to understand early events in ovarian cancers. We are also using natural products to uncover new progestins and anti-cancer molecules.

Awards and Honors

  • 2013, UIC Researcher of the Year Rising Star, UIC
  • 2010, Liz Tilberis Scholar, Ovarian Cancer Research Fund

Intellectual Contributions

Journal Article

  • Dean MJ, Jin V, Russo A, Lantvit DD, Burdette JE. "Exposure of the extracellular matrix and colonization of the ovary in metastasis of fallopian-tube-derived cancer.". Carcinogenesis. 2019;40(1):41-51. doi:10.1093/carcin/bgy170.
  • Ren Y, de Blanco EJC , Fuchs JR, Soejarto DD, Burdette JE, Swanson SM, Kinghorn AD. "Potential Anticancer Agents Characterized from Selected Tropical Plants.". Journal of natural products. 2019;. doi:10.1021/acs.jnatprod.9b00018.
  • Benatrehina PA, Chen W, Czarnecki A, Kurina S, Chai HB, Lantvit DD, Ninh TN, Zhang X, Soejarto DD, Burdette JE, Kinghorn AD, Rakotondraibe LH. "Bioactivity-Guided Isolation of Totarane-Derived Diterpenes from Podocarpus neriifolius and Structure Revision of 3-Deoxy-2α-hydroxynagilactone E.". Natural products and bioprospecting. 2019;. doi:10.1007/s13659-019-0198-x.
  • Petukhova V, Young A, Wang J, Wang M, Ladanyi A, Kothari R, Burdette JE, Sanchez L. "Whole Cell MALDI Fingerprinting Is a Robust Tool for Differential Profiling of Two-Component Mammalian Cell Mixtures.". Journal of the American Society for Mass Spectrometry. 2019;30(2):344-354. doi:10.1007/s13361-018-2088-6.
  • El-Elimat T, Raja HA, Ayers S, Kurina S, Burdette JE, Mattes Z, Sabatelle R, Bacon JW, Colby AH, Grinstaff MW, Pearce CJ, Oberlies NH. "Meroterpenoids from Neosetophoma sp.: A Dioxa[4.3.3]propellane Ring System, Potent Cytotoxicity, and Prolific Expression.". Organic letters. 2019;. doi:10.1021/acs.orglett.8b03769.
  • Zink KE, Dean MJ, Burdette JE, Sanchez L. "Imaging Mass Spectrometry Reveals Crosstalk between the Fallopian Tube and the Ovary that Drives Primary Metastasis of Ovarian Cancer.". ACS central science. 2018;4(10):1360-1370. doi:10.1021/acscentsci.8b00405.
  • Al-Huniti MH, Rivera-Chávez J, Colón KL, Stanley JL, Burdette JE, Pearce CJ, Oberlies NH, Croatt MP. "Development and Utilization of a Palladium-Catalyzed Dehydration of Primary Amides To Form Nitriles.". Organic letters. 2018;20(19):6046-6050. doi:10.1021/acs.orglett.8b02422.
  • Young A, Herrera D, Huntsman AC, Korkmaz MA, Lantvit DD, Mazumder S, Kolli S, Coss CC, King S, Wang H, Swanson SM, Kinghorn AD, Zhang X, Phelps MA, Aldrich LN, Fuchs JR, Burdette JE. "Phyllanthusmin Derivatives Induce Apoptosis and Reduce Tumor Burden in High-Grade Serous Ovarian Cancer by Late-Stage Autophagy Inhibition.". Molecular cancer therapeutics. 2018;17(10):2123-2135. doi:10.1158/1535-7163.MCT-17-1195.
  • Karthikeyan S, Russo A, Dean MJ, Lantvit DD, Endsley M, Burdette JE. "Prolactin signaling drives tumorigenesis in human high grade serous ovarian cancer cells and in a spontaneous fallopian tube derived model.". Cancer letters. 2018;433:221-231. doi:10.1016/j.canlet.2018.07.003.
  • Crnkovic C, Krunic A, May DS, Wilson TA, Kao D, Burdette JE, Fuchs JR, Oberlies NH, Orjala J. "Calothrixamides A and B from the Cultured Cyanobacterium Calothrix sp. UIC 10520.". Journal of natural products. 2018;81(9):2083-2090. doi:10.1021/acs.jnatprod.8b00432.
  • Lee J, Dean MJ, Austin J, Burdette JE, Murphy BT. "Irilone from Red Clover ( Trifolium pratense) Potentiates Progesterone Signaling.". Journal of natural products. 2018;81(9):1962-1967. doi:10.1021/acs.jnatprod.8b00131.
  • Ren Y, Anaya-Eugenio GD, Czarnecki A, Ninh TN, Yuan C, Chai HB, Soejarto DD, Burdette JE, de Blanco EJC , Kinghorn AD. "Cytotoxic and NF-κB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives.". Bioorganic & medicinal chemistry. 2018;26(15):4452-4460. doi:10.1016/j.bmc.2018.07.025.
  • Hardy LR, Salvi A, Burdette JE. "UnPAXing the Divergent Roles of PAX2 and PAX8 in High-Grade Serous Ovarian Cancer.". Cancers. 2018;10(8). doi:10.3390/cancers10080262.
  • El-Elimat T, Rivera-Chávez J, Burdette JE, Czarnecki A, Alhawarri MB, Al-Gharaibeh M, Alali F, Oberlies NH. "Cytotoxic homoisoflavonoids from the bulbs of Bellevalia flexuosa.". Fitoterapia. 2018;127:201-206. doi:10.1016/j.fitote.2018.02.022.
  • Woodard JL, Huntsman AC, Patel PA, Chai HB, Kanagasabai R, Karmahapatra S, Young A, Ren Y, Cole MS, Herrera D, Yalowich JC, Kinghorn AD, Burdette JE, Fuchs JR. "Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones.". Bioorganic & medicinal chemistry. 2018;26(9):2354-2364. doi:10.1016/j.bmc.2018.03.033.
  • Dean MJ, Austin J, Jinhong R, Johnson ME, Lantvit DD, Burdette JE. "The Flavonoid Apigenin Is a Progesterone Receptor Modulator with In Vivo Activity in the Uterus.". Hormones & cancer. 2018;. doi:10.1007/s12672-018-0333-x.
  • Russo A, Czarnecki A, Dean MJ, Modi DA, Lantvit DD, Hardy L, Baligod S, Davis DA, Wei JJ, Burdette JE. "PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation.". Oncogene. 2018;37(15):1976-1990. doi:10.1038/s41388-017-0097-8.
  • May DS, Kang HS, Santarsiero BD, Krunic A, Shen Q, Burdette JE, Swanson SM, Orjala J. "Ribocyclophanes A-E, Glycosylated Cyclophanes with Antiproliferative Activity from Two Cultured Terrestrial Cyanobacteria.". Journal of natural products. 2018;81(3):572-578. doi:10.1021/acs.jnatprod.7b00954.
  • Sica VP, Rees ER, Raja HA, Rivera-Chávez J, Burdette JE, Pearce CJ, Oberlies NH. "In situ mass spectrometry monitoring of fungal cultures led to the identification of four peptaibols with a rare threonine residue". Phytochemistry. 2017;143:45-53. doi:10.1016/j.phytochem.2017.07.004.
  • Rivera-Chávez J, Raja HA, Graf TN, Burdette JE, Pearce CJ, Oberlies NH. "Biosynthesis of Fluorinated Peptaibols Using a Site-Directed Building Block Incorporation Approach". Journal of Natural Products. 2017;80(6):1883-1892. doi:10.1021/acs.jnatprod.7b00189.
  • Modi DA, Tagare RD, Karthikeyan S, Russo A, Dean MJ, Davis DA, Lantvit DD, Burdette JE. "PAX2 function, regulation and targeting in fallopian tube-derived high-grade serous ovarian cancer". Oncogene. 2017;36(21):3015-3024. doi:10.1038/onc.2016.455.
  • Olalekan SA, Burdette JE, Getsios S, Woodruff TK, Julie Kim J. "Development of a novel human recellularized endometrium that responds to a 28-day hormone treatment". Biology of Reproduction. 2017;96(5):971-981. doi:10.1093/biolre/iox039.
  • May DS, Chen WL, Lantvit DD, Zhang X, Krunic A, Burdette JE, Eustaquio A, Orjala J. "Merocyclophanes C and D from the Cultured Freshwater Cyanobacterium Nostoc sp. (UIC 10110)". Journal of Natural Products. 2017;80(4):1073-1080. doi:10.1021/acs.jnatprod.6b01175.
  • Dean MJ, Davis DA, Burdette JE. "Activin A stimulates migration of the fallopian tube epithelium, an origin of high-grade serous ovarian cancer, through non-canonical signaling". Cancer Letters. 2017;391:114-124. doi:10.1016/j.canlet.2017.01.011.
  • Xiao S, Coppeta JR, Rogers HB, Isenberg BC, Zhu J, Olalekan SA, McKinnon KE, Dokic D, Rashedi AS, Haisenleder DJ, Malpani SS, Arnold-Murray CA, Chen K, Jiang M, Bai L, Nguyen CT, Zhang J, Laronda MM, Hope TJ, Maniar KP, Pavone ME, Avram MJ, Sefton EC, Getsios S, Burdette JE, Kim JJ, Borenstein JT, Woodruff TK. "A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle". Nature Communications. 2017;8. doi:10.1038/ncomms14584.
  • Paguigan ND, Al-Huniti MH, Raja HA, Czarnecki A, Burdette JE, González-Medina M, Medina-Franco JL, Polyak SJ, Pearce CJ, Croatt MP, Oberlies NH. "Chemoselective fluorination and chemoinformatic analysis of griseofulvin: Natural vs fluorinated fungal metabolites". Bioorganic and Medicinal Chemistry. 2017;25(20):5238-5246. doi:10.1016/j.bmc.2017.07.041.
  • Zhu J, Xu Y, Rashedi AS, Pavone ME, Julie Kim J, Woodruff TK, Burdette JE. "Human fallopian tube epithelium co-culture with murine ovarian follicles reveals crosstalk in the reproductive cycle". Molecular Human Reproduction. 2016;22(11):756-767. doi:10.1093/molehr/gaw041.
  • Guo BC, Onakpa MM, Huang XJ, Santarsiero BD, Chen WL, Zhao M, Zhang XQ, Swanson SM, Burdette JE, Che CT. "Di-nor- and 17-nor-pimaranes from Icacina trichantha". Journal of Natural Products. 2016;79(7):1815-1821. doi:10.1021/acs.jnatprod.6b00289.
  • Rodgers L, hAinmhire E, Young A, Burdette JE. "Loss of PAX8 in high-grade serous ovarian cancer reduces cell survival despite unique modes of action in the fallopian tube and ovarian surface epithelium". Oncotarget. 2016;7(22):32785-32795. doi:10.18632/oncotarget.9051.
  • Moyle-Heyrman G, Schipma MJ, Dean MJ, Davis DA, Burdette JE. "Genome-wide transcriptional regulation of estrogen receptor targets in fallopian tube cells and the role of selective estrogen receptor modulators". Journal of Ovarian Research. 2016;9(1). doi:10.1186/s13048-016-0213-3.
  • Chen WL, Pan L, Kinghorn AD, Swanson SM, Burdette JE. "Silvestrol induces early autophagy and apoptosis in human melanoma cells". BMC Cancer. 2016;16(1). doi:10.1186/s12885-015-1988-0.
  • Karthikeyan S, Lantvit DD, Chae DH, Burdette JE. "Cadherin - 6 type 2, K- cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface". Oncotarget. 2016;7(43):69871-69882. doi:10.18632/oncotarget.11499.
  • Zhao M, Onakpa MM, Santarsiero BD, Chen W, Szymulanska-Ramamurthy KM, Swanson SM, Burdette JE, Che C. "(9βH)-Pimaranes and Derivatives from the Tuber of Icacina trichantha.". Journal of natural products. 2015;. doi:10.1021/acs.jnatprod.5b00688.
  • Mitra AK, Davis DA, Tomar S, Roy L, Gurler H, Xie J, Lantvit DD, Cardenas H, Fang F, Liu Y, Loughran E, Yang J, Sharon Stack M, Emerson RE, Cowden Dahl KD, Barbolina M, Nephew KP, Matei D, Burdette JE. "In vivo tumor growth of high-grade serous ovarian cancer cell lines.". Gynecologic oncology. 2015;138(2):372-7. doi:10.1016/j.ygyno.2015.05.040.
  • Endsley MP, Heyrman GE, Karthikeyan S, Lantvit DD, Davis DA, Wei J, Burdette JE. "Spontaneous Transformation of Murine Oviductal Epithelial Cells: A Model System to Investigate the Onset of Fallopian-Derived Tumors". Frontiers in Oncology. 2015;. doi:10.3389/fonc.2015.00154.
  • Zhao M, Onakpa MM, Chen W, Santarsiero BD, Swanson SM, Burdette JE, Asuzu IU, Che C. "17-Norpimaranes and (9βH)-17-Norpimaranes from the Tuber of Icacina trichantha.". Journal of natural products. 2015;78(4):789-96. doi:10.1021/np5010328.
  • Arslan SY, Yu Y, Burdette JE, Pavone ME, Hope TJ, Woodruff TK, Kim JJ. "Novel three dimensional human endocervix cultures respond to 28-day hormone treatment.". Endocrinology. 2015;156(4):1602-9. doi:10.1210/en.2014-1840.
  • Quartuccio SM, Karthikeyan S, Eddie SL, Lantvit DD, hAinmhire E, Modi DA, Wei JJ, Burdette JE. "Mutant p53 expression in fallopian tube epithelium drives cell migration.". International journal of cancer. Journal international du cancer. 2015;. doi:10.1002/ijc.29528.
  • Zhao M, Onakpa MM, Chen W, Santarsiero BD, Swanson SM, Burdette JE, Asuzu IU, Che C. "17-Norpimaranes and (9βH)-17-Norpimaranes from the Tuber of Icacina trichantha.". Journal of natural products. 2015;. doi:10.1021/np5010328.
  • Eddie SL, Quartuccio SM, Zhu J, Shepherd JA, Kothari R, Kim JJ, Woodruff TK, Burdette JE. "Three-dimensional modeling of the human fallopian tube fimbriae.". Gynecologic oncology. 2015;136(2):348-54. doi:10.1016/j.ygyno.2014.12.015.
  • Mitra AK, Davis DA, Tomar S, Roy L, Gurler H, Xie J, Lantvit DD, Cardenas H, Fang F, Liu Y, Loughran E, Yang J, Sharon Stack M, Emerson RE, Cowden Dahl KD, Barbolina M, Nephew KP, Matei D, Burdette JE. "In vivo tumor growth of high-grade serous ovarian cancer cell lines". Gynecologic Oncology. 2015;138(2):372-377. doi:10.1016/j.ygyno.2015.05.040.
  • Quartuccio SM, Karthikeyan S, Eddie SL, Lantvit DD, Hainmhire EO, Modi DA, Wei JJ, Burdette JE. "Mutant p53 expression in fallopian tube epithelium drives cell migration". International Journal of Cancer. 2015;137(7):1528-1538. doi:10.1002/ijc.29528.
  • Arslan SY, Yu Y, Burdette JE, Pavone ME, Hope TJ, Woodruff TK, Kim JJ. "Novel three dimensional human endocervix cultures respond to 28-day hormone treatment". Endocrinology. 2015;156(4):1602-1609. doi:10.1210/en.2014-1840.
  • Endsley MP, Moyle-Heyrman G, Karthikeyan S, Lantvit DD, Davis DA, Wei JJ, Burdette JE. "Spontaneous transformation of murine oviductal epithelial cells: A model system to investigate the onset of fallopian-derived tumors". Frontiers in Oncology. 2015;5(JUN). doi:10.3389/fonc.2015.00154.
  • Eddie SL, Quartuccio SM, Zhu J, Shepherd JA, Kothari R, Kim JJ, Woodruff TK, Burdette JE. "Three-dimensional modeling of the human fallopian tube fimbriae". Gynecologic Oncology. 2015;136(2):348-354. doi:10.1016/j.ygyno.2014.12.015.
  • Eddie SL, Quartuccio SM, hAinmhire E, Moyle-Heyrman G, Lantvit DD, Wei JJ, Vanderhyden BC, Burdette JE. "Tumorigenesis and peritoneal colonization from fallopian tube epithelium". Oncotarget. 2015;6(24):20500-20512. doi:10.18632/oncotarget.3985.
  • Zhang Q, Burdette JE, Wang JP. "Integrative network analysis of TCGA data for ovarian cancer.". BMC systems biology. 2014;8(1):1338. doi:10.1186/s12918-014-0136-9.
  • Sunoqrot S, Bugno JM, Lantvit DD, Burdette JE, Hong S. "Prolonged blood circulation and enhanced tumor accumulation of folate-targeted dendrimer-polymer hybrid nanoparticles.". Journal of controlled release : official journal of the Controlled Release Society. 2014;191:115-22. doi:10.1016/j.jconrel.2014.05.006.
  • Eddie SL, Kim JJ, Woodruff TK, Burdette JE. "Microphysiological modeling of the reproductive tract: a fertile endeavor.". Experimental biology and medicine (Maywood, N.J.). 2014;239(9):1192-202. doi:10.1177/1535370214529387.
  • Townsend TR, Moyle-Heyrman G, Sukerkar PA, MacRenaris KW, Burdette JE, Meade TJ. "Progesterone-targeted magnetic resonance imaging probes". Bioconjugate Chemistry. 2014;25(8):1428-1437. doi:10.1021/bc500265h.
  • Townsend TR, Moyle-Heyrman G, Sukerkar PA, MacRenaris KW, Burdette JE, Meade TJ. "Progesterone-targeted magnetic resonance imaging probes.". Bioconjugate chemistry. 2014;25(8):1428-37. doi:10.1021/bc500265h.
  • Lengyel E, Burdette JE, Kenny HA, Matei D, Pilrose J, Haluska P, Nephew KP, Hales DB, Stack MS. "Epithelial ovarian cancer experimental models.". Oncogene. 2014;33(28):3619-33. doi:10.1038/onc.2013.321.
  • Desjardins M, Xie J, Gurler H, Muralidhar GG, Sacks JD, Burdette JE, Barbolina M. "Versican regulates metastasis of epithelial ovarian carcinoma cells and spheroids". Journal of Ovarian Research. 2014;7(1). doi:10.1186/1757-2215-7-70.
  • Mullowney MW, hAinmhire E, Shaikh AF, Wei X, Tanouye U, Santarsiero BD, Burdette JE, Murphy BT. "Diazaquinomycins E-G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp.". Marine drugs. 2014;12(6):3574-86. doi:10.3390/md12063574.
  • Mullowney MW, hAinmhire E, Shaikh AF, Wei X, Tanouye U, Santarsiero BD, Burdette JE, Murphy BT. "Diazaquinomycins E-G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp.". Marine drugs. 2014;12(6):3574-86. doi:10.3390/md12063574.
  • Modi DA, Sunoqrot S, Bugno JM, Lantvit DD, Hong S, Burdette JE. "Targeting of follicle stimulating hormone peptide-conjugated dendrimers to ovarian cancer cells". Nanoscale. 2014;6(5):2812-2820. doi:10.1039/c3nr05042d.
  • Modi DA, Sunoqrot S, Bugno JM, Lantvit DD, Hong S, Burdette JE. "Targeting of follicle stimulating hormone peptide-conjugated dendrimers to ovarian cancer cells.". Nanoscale. 2014;6(5):2812-20. doi:10.1039/c3nr05042d.
  • HAinmhire E, Quartuccio SM, Cheng W, Ahmed RA, King SM, Burdette JE. "Mutation or loss of p53 differentially modifies TGFβ action in ovarian cancer". PLoS ONE. 2014;9(2). doi:10.1371/journal.pone.0089553.
  • Mullowney MW, Ó hAinmhire E, Shaikh AF, Wei X, Tanouye U, Santarsiero BD, Burdette JE, Murphy BT. "Diazaquinomycins E-G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp.". Marine Drugs. 2014;12(6):3574-3586. doi:10.3390/md12063574.
  • Zhang Q, Burdette JE, Wang JP. "Integrative network analysis of TCGA data for ovarian cancer". BMC systems biology. 2014;8:1338. doi:10.1186/s12918-014-0136-9.
  • Toh MF, Mendonca E, Eddie SL, Endsley MP, Lantvit DD, Petukhov PA, Burdette JE. "Kaempferol Exhibits Progestogenic Effects in Ovariectomized Rats.". Journal of steroids & hormonal science. 2014;5(3):136. doi:10.4172/2157-7536.1000136.
  • Eddie SL, Kim JJ, Woodruff TK, Burdette JE. "Microphysiological modeling of the reproductive tract: A fertile endeavor". Experimental Biology and Medicine. 2014;239(9):1192-1202. doi:10.1177/1535370214529387.
  • hAinmhire E, Quartuccio SM, Cheng W, Ahmed RA, King SM, Burdette JE. "Mutation or loss of p53 differentially modifies TGFβ action in ovarian cancer.". PloS one. 2014;9(2):e89553. doi:10.1371/journal.pone.0089553.
  • Desjardins M, Xie J, Gurler H, Muralidhar G, Sacks JD, Burdette JE, Barbolina M. "Versican regulates metastasis of epithelial ovarian carcinoma cells and spheroids.". Journal of ovarian research. 2014;7:70. doi:10.1186/1757-2215-7-70.
  • Quartuccio SM, Lantvit DD, Bosland MC, Burdette JE. "Conditional Inactivation of p53 in Mouse Ovarian Surface Epithelium Does Not Alter MIS Driven Smad2-Dominant Negative Epithelium-Lined Inclusion Cysts or Teratomas". PLoS ONE. 2013;8(5). doi:10.1371/journal.pone.0065067.
  • Quartuccio SM, Lantvit DD, Bosland MC, Burdette JE. "Conditional inactivation of p53 in mouse ovarian surface epithelium does not alter MIS driven Smad2-dominant negative epithelium-lined inclusion cysts or teratomas.". PloS one. 2013;8(5):e65067. doi:10.1371/journal.pone.0065067.
  • King SM, Quartuccio SM, Vanderhyden BC, Burdette JE. "Early transformative changes in normal ovarian surface epithelium induced by oxidative stress require Akt upregulation, DNA damage and epithelial-stromal interaction". Carcinogenesis. 2013;34(5):1125-1133. doi:10.1093/carcin/bgt003.
  • King SM, Quartuccio SM, Vanderhyden BC, Burdette JE. "Early transformative changes in normal ovarian surface epithelium induced by oxidative stress require Akt upregulation, DNA damage and epithelial-stromal interaction.". Carcinogenesis. 2013;34(5):1125-33. doi:10.1093/carcin/bgt003.
  • Hilliard TS, Modi DA, Burdette JE. "Gonadotropins activate oncogenic pathways to enhance proliferation in normal mouse ovarian surface epithelium". International Journal of Molecular Sciences. 2013;14(3):4762-4782. doi:10.3390/ijms14034762.
  • Hilliard TS, Modi DA, Burdette JE. "Gonadotropins activate oncogenic pathways to enhance proliferation in normal mouse ovarian surface epithelium.". International journal of molecular sciences. 2013;14(3):4762-82. doi:10.3390/ijms14034762.
  • King SM, Modi DA, Eddie SL, Burdette JE. "Insulin and insulin-like growth factor signaling increases proliferation and hyperplasia of the ovarian surface epithelium and decreases follicular integrity through upregulation of the PI3-kinase pathway.". Journal of ovarian research. 2013;6(1):12. doi:10.1186/1757-2215-6-12.
  • Laronda MM, Burdette JE, Kim J, Woodruff TK. "Recreating the female reproductive tract in vitro using iPSC technology in a linked microfluidics environment.". Stem cell research & therapy. 2013;4 Suppl 1:S13. doi:10.1186/scrt374.
  • Kim M, Rooper L, Xie J, Rayahin JE, Burdette JE, Kajdacsy-Balla AA, Barbolina M. "The lymphotactin receptor is expressed in epithelial ovarian carcinoma and contributes to cell migration and proliferation.". Molecular cancer research : MCR. 2012;10(11):1419-29. doi:10.1158/1541-7786.MCR-12-0361.
  • Toh MF, Sohn J, Chen S, Yao P, Bolton JL, Burdette JE. "Biological characterization of non-steroidal progestins from botanicals used for women's health.". Steroids. 2012;77(7):765-73. doi:10.1016/j.steroids.2012.03.013.
  • Sukerkar PA, MacRenaris KW, Townsend TR, Ahmed RA, Burdette JE, Meade TJ. "Synthesis and biological evaluation of water-soluble progesterone-conjugated probes for magnetic resonance imaging of hormone related cancers.". Bioconjugate chemistry. 2011;22(11):2304-16. doi:10.1021/bc2003555.
  • Hilliard TS, Gaisina IN, Muehlbauer AG, Gaisin AM, Gallier F, Burdette JE. "Glycogen synthase kinase 3β inhibitors induce apoptosis in ovarian cancer cells and inhibit in-vivo tumor growth.". Anti-cancer drugs. 2011;22(10):978-85. doi:10.1097/CAD.0b013e32834ac8fc.
  • King SM, Hilliard TS, Wu LY, Jaffe RC, Fazleabas AT, Burdette JE. "The impact of ovulation on fallopian tube epithelial cells: evaluating three hypotheses connecting ovulation and serous ovarian cancer.". Endocrine-related cancer. 2011;18(5):627-42. doi:10.1530/ERC-11-0107.
  • Sukerkar PA, MacRenaris KW, Meade TJ, Burdette JE. "A steroid-conjugated magnetic resonance probe enhances contrast in progesterone receptor expressing organs and tumors in vivo.". Molecular pharmaceutics. 2011;8(4):1390-400. doi:10.1021/mp200219e.
  • King SM, Burdette JE. "Evaluating the progenitor cells of ovarian cancer: analysis of current animal models.". BMB reports. 2011;44(7):435-45. doi:DOI 10.5483/BMBRep.2011.44.7.435.
  • King SM, Quartuccio S, Hilliard TS, Inoue K, Burdette JE. "Alginate hydrogels for three-dimensional organ culture of ovaries and oviducts.". Journal of visualized experiments : JoVE. 2011;(52). doi:10.3791/2804.
  • Toh MF, Burdette JE. "Identifying botanical mechanisms of action.". Fitoterapia. 2011;82(1):67-70. doi:10.1016/j.fitote.2010.09.003.
  • Sinkevicius KW, Woloszyn K, Laine M, Jackson KS, Greene GL, Woodruff TK, Burdette JE. "Characterization of the ovarian and reproductive abnormalities in prepubertal and adult estrogen non-responsive estrogen receptor alpha knock-in (ENERKI) mice.". Steroids. 2009;74(12):913-9. doi:10.1016/j.steroids.2009.06.012.
  • Jackson KS, Inoue K, Davis DA, Hilliard TS, Burdette JE. "Three-dimensional ovarian organ culture as a tool to study normal ovarian surface epithelial wound repair.". Endocrinology. 2009;150(8):3921-6. doi:10.1210/en.2008-1674.
  • Sinkevicius KW, Burdette JE, Woloszyn K, Hewitt SC, Hamilton K, Sugg SL, Temple KA, Wondisford FE, Korach KS, Woodruff TK, Greene GL. "An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo.". Endocrinology. 2008;149(6):2970-9. doi:10.1210/en.2007-1526.
  • Burdette JE. "In vivo imaging of molecular targets and their function in endocrinology.". Journal of molecular endocrinology. 2008;40(6):253-61. doi:10.1677/JME-07-0170.
  • Burdette JE, Woodruff TK. "Activin and estrogen crosstalk regulates transcription in human breast cancer cells.". Endocrine-related cancer. 2007;14(3):679-89. doi:10.1677/ERC-07-0054.
  • Burdette JE, Oliver RM, Ulyanov V, Kilen SM, Mayo KE, Woodruff TK. "Ovarian epithelial inclusion cysts in chronically superovulated CD1 and Smad2 dominant-negative mice.". Endocrinology. 2007;148(8):3595-604. doi:10.1210/en.2007-0030.
  • , Burdette JE, MacRenaris KW, Mustafi D, Woodruff TK, Meade TJ. "Rational design, synthesis, and biological evaluation of progesterone-modified MRI contrast agents.". Chemistry & biology. 2007;14(7):824-34. doi:10.1016/j.chembiol.2007.06.006.
  • Burdette JE, Kurley SJ, Kilen SM, Mayo KE, Woodruff TK. "Gonadotropin-induced superovulation drives ovarian surface epithelia proliferation in CD1 mice.". Endocrinology. 2006;147(5):2338-45. doi:10.1210/en.2005-1629.
  • Booth NL, Overk CR, Yao P, Burdette JE, Nikolic DS, Chen S, Bolton JL, van Breemen RB, Pauli GF, Farnsworth NR. "The chemical and biologic profile of a red clover (Trifolium pratense L.) phase II clinical extract.". Journal of alternative and complementary medicine (New York, N.Y.). 2006;12(2):133-9. doi:10.1089/acm.2006.12.133.
  • , Zylka MJ, Anderson DJ, Burdette JE, Woodruff TK, Meade TJ. "A steroid-conjugated contrast agent for magnetic resonance imaging of cell signaling.". Journal of the American Chemical Society. 2005;127(38):13164-6. doi:10.1021/ja051294x.
  • Burdette JE, Jeruss JS, Kurley SJ, Lee E, Woodruff TK. "Activin A mediates growth inhibition and cell cycle arrest through Smads in human breast cancer cells.". Cancer research. 2005;65(17):7968-75. doi:10.1158/0008-5472.CAN-04-3553.
  • Chadwick LR, Nikolic DS, Burdette JE, Overk CR, Bolton JL, van Breemen RB, Fröhlich R, Fong HH, Farnsworth NR, Pauli GF. "Estrogens and congeners from spent hops (Humulus lupulus).". Journal of natural products. 2004;67(12):2024-32. doi:10.1021/np049783i.
  • Piersen CE, Booth NL, Sun Y, Liang W, Burdette JE, van Breemen RB, Geller SE, Gu C, Banuvar S, Shulman LP, Bolton JL, Farnsworth NR. "Chemical and biological characterization and clinical evaluation of botanical dietary supplements: a phase I red clover extract as a model.". Current medicinal chemistry. 2004;11(11):1361-74.
  • Liu J, Burdette JE, Sun Y, Deng S, Schlecht SM, Zheng W, Nikolic DS, Mahady GB, van Breemen RB, Fong HH, Pezzuto JM, Bolton JL, Farnsworth NR. "Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry).". Phytomedicine : international journal of phytotherapy and phytopharmacology. 2004;11(1):18-23. doi:10.1078/0944-7113-00331.
  • Burdette JE, Liu J, Chen S, Piersen CE, Barker EL, Pezzuto JM, Mesecar A, van Breemen RB, Farnsworth NR, Bolton JL. "Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor.". Journal of agricultural and food chemistry. 2003;51(19):5661-70. doi:10.1021/jf034264r.
  • Liu X, Pisha E, Tonetti D, Yao D, Li Y, Yao J, Burdette JE, Bolton JL. "Antiestrogenic and DNA damaging effects induced by tamoxifen and toremifene metabolites.". Chemical research in toxicology. 2003;16(7):832-7. doi:10.1021/tx030004s.
  • Liu X, Zhang F, Liu H, Burdette JE, Li Y, Overk CR, Pisha E, Yao J, van Breemen RB, Swanson SM, Bolton JL. "Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin.". Chemical research in toxicology. 2003;16(6):741-9. doi:10.1021/tx030001f.
  • Johnson BM, Qiu SX, Zhang S, Zhang F, Burdette JE, Yu L, Bolton JL, van Breemen RB. "Identification of novel electrophilic metabolites of piper methysticum Forst (Kava).". Chemical research in toxicology. 2003;16(6):733-40. doi:10.1021/tx020113r.
  • Gafner S, Bergeron C, Batcha LL, Reich J, Arnason JT, Burdette JE, Pezzuto JM, Angerhofer CK. "Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora.". Journal of natural products. 2003;66(4):535-7. doi:10.1021/np0205102.
  • Calderón AI, Terreaux C, Schenk K, Pattison P, Burdette JE, Pezzuto JM, Gupta MP, Hostettmann K. "Isolation and structure elucidation of an isoflavone and a sesterterpenoic acid from Henriettella fascicularis.". Journal of natural products. 2002;65(12):1749-53. doi:10.1021/np0201164.
  • Burdette JE, Chen S, Lu ZZ, Xu H, White B, Liu J, Fong HH, Farnsworth NR, Constantinou AI, van Breemen RB, Pezzuto JM, Bolton JL. "Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles.". Journal of agricultural and food chemistry. 2002;50(24):7022-8.
  • Burdette JE, Liu J, Lantvit DD, Lim E, Booth N, Bhat KP, Hedayat S, van Breemen RB, Constantinou AI, Pezzuto JM, Farnsworth NR, Bolton JL. "Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized Sprague-Dawley rats.". The Journal of nutrition. 2002;132(1):27-30.
  • Liu J, Burdette JE, Xu H, Gu C, van Breemen RB, Bhat KP, Booth N, Constantinou AI, Pezzuto JM, Fong HH, Farnsworth NR, Bolton JL. "Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms.". Journal of agricultural and food chemistry. 2001;49(5):2472-9.

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