Andrew Riley
Associate Professor, College of Pharmacy - Pharmaceutical Sciences
Email:
Related Sites:
About
Teaching and Supervision
PSCI Ph.D. Thesis Research (PSCI 599), 8/25/2025 – 12/5/2025
Research Presentation (PSCI 502), 8/25/2025 – 12/5/2025
Fundamentals of Drug Action (PHAR 422), 8/25/2025 – 12/5/2025
Fundamentals of Drug Action (PHAR 422), 8/25/2025 – 12/5/2025
Undergrad Res Exp Pharm Sci (PSCI 300), 8/25/2025 – 12/5/2025
PSCI Ph.D. Thesis Research (PSCI 599), 6/16/2025 – 8/8/2025
PSCI Ph.D. Thesis Research (PSCI 599), 1/13/2025 – 5/2/2025
Research Presentation (PSCI 502), 8/26/2024 – 12/6/2024
Doctoral Restch in Med Chem (MDCH 599), 8/26/2024 – 12/6/2024
Selected Grants
Pharmacological Potential of Combined Translation and Autophagy Inhibition in High Grade Serous Ovarian Cancer, National Institutes of Health (National Institute of General Medical Sciences)., 8/1/2024 - 7/31/2026, Obligated Amount: $241944; Anticipated Amount: $241944
?9?10 Nicotinic Acetylcholine Receptors in neuropathic pain, National Institutes of Health (National Institute of Neurological Disorders and Stroke)., 8/1/2024 - 6/30/2029, Obligated Amount: $1248720; Anticipated Amount: $3121800
α9α10 Nicotinic Acetylcholine Receptors in neuropathic pain, National Institute of Neurological Disorders and Stroke., 8/1/2024 - 6/30/2029, Obligated Amount: $1248720; No Anticipated Amount Set
Aristotelia Alkaloids as Probes for the Nicotinic Acetylcholine Receptors, National Institutes of Health (National Center for Complementary and Integrative Health)., 5/16/2024 - 5/15/2026, Obligated Amount: $98512; Anticipated Amount: $98512
Selective Targeting of Nicotinic Acetylcholine Receptor Subtypes for Cocaine Use Disorder, National Institutes of Health (National Institute on Drug Abuse)., 3/1/2024 - 12/31/2028, Obligated Amount: $1393000; Anticipated Amount: $3373690
Defining ?9?10 nAChR Complex Using the ATLAS Kit, Sigma-Aldrich., 12/16/2022 - 9/15/2023, Obligated Amount: $30000; Anticipated Amount: $30000
Prodrug Development for Pharmaceutical Uses, Innovo Pharmaceuticals., 9/16/2022 - 9/15/2024, Obligated Amount: $44793; Anticipated Amount: $44793
Synthesis and Evaluation of Alkaloids to Probe Membrane Receptors, National Institutes of Health (National Institute of General Medical Sciences)., 8/1/2022 - 6/30/2027, Obligated Amount: $1905708; Anticipated Amount: $2097885
Hans W. Vahlteich Research Award, UIC College of Pharmacy., Date Not Set - Present, No Obligated Amount Set; No Anticipated Amount Set
Selected Publications
Bigi-Botterill, Simone V, Borsari, Chiara, Dombrowski, Amanda W, Estrada, Michelle A, Farrell, Mark P, Riley, AndrewP, Woodland, John G. (2026). Fifteen Years, One Mission: Innovative, Inspirational, and Impactful Discoveries. ACS Medicinal Chemistry Letters, 17, (1), 1-19. doi:10.1021/acsmedchemlett.5c00709.
Heppner, David E, Bigi-Botterill, Simone V, Riley, Andrew P, Chibale, Kelly, Lindsley, Craig W. (2025). Structural Biology Enabling Drug Discovery. Journal of Medicinal Chemistry, 68, (22), 23641-23642. doi:10.1021/acs.jmedchem.5c03093.
Riley, Andrew P. (2025). Semi-synthesis in the exploration of opioid-targeting natural products. Natural Product Reports, 42, (10), 1664-1675. doi:10.1039/d5np00029g.
Riley, Andrew P. (2025). In This Issue, Volume 16, Issue 9. ACS Medicinal Chemistry Letters, 16, (9), 1688-1689. doi:10.1021/acsmedchemlett.5c00497.
Gour, Abhishek, Creed, Simone M, Riley, Andrew P, Sharma, Abhisheak. (2025). Comprehensive pharmacokinetics and ADME evaluation of Akuamma alkaloids. Journal of Chromatography B, 1263, 124713. doi:10.1016/j.jchromb.2025.124713.
Riley, Andrew P. (2025). In This Issue, Volume 16, Issue 8. ACS Medicinal Chemistry Letters, 16, (8), 1435-1436. doi:10.1021/acsmedchemlett.5c00429.
Riley, Andrew P. (2025). In This Issue, Volume 16, Issue 4. ACS Medicinal Chemistry Letters, 16, (5), 702-703. doi:10.1021/acsmedchemlett.5c00151.
Bland, Kathryn, Chen, Chongguang, Huang, Peng, Ho, Conrad, Howe, Theodora, Ocampo, Katrina, Zhao, Pingwei, Creed, Simone, Noel-Torres, Joseph, Riley, Andrew P, Liu-Chen, Lee-Yuan. (2025). Pharmacological characterization of the novel selective kappa opioid receptor agonists 10-Iodo-Akuammicine and 10-Bromo-akuammicine in mice. Neuropharmacology, 268, 110316. doi:10.1016/j.neuropharm.2025.110316.
Straub, Carolyn J, Rusali, Lisa E, Riley, Andrew P. (2025). Derivatives of Aristoquinoline Accessed through a Ritter-like Reaction. ACS Medicinal Chemistry Letters, 16, (3), 406-409. doi:10.1021/acsmedchemlett.4c00506.
Professional Leadership
Auditing Committee, American Society of Pharmacognosy, 8/7/2019 - Present
Auditing Committee, 8/7/2019 - Present
Notable Honors
2024, ACS MEDI Young Investigator Symposium, American Chemical Society
2024, UIC Rising Star in Basic Life Sciences, UIC
2023, Thieme Chemistry Journal Award, Thieme Journals
Education
Degrees:
BA, Ohio Wesleyan University, United States, 2010
PhD, The University of Kansas, USA, 2015
Postgraduate Training:
NRSA Postdoctoral Fellowship (NIH-F32), University of Illinois at Urbana-Champaign, United States, 2018