Bernard Santarsiero
Research Professor, Pharmaceutical Sciences
Director, Research Initiatives, Graduate College
Director, Research Initiatives, Vice Chancellor for Research
Associate, Pharmacognosy Institute
Program Coordinator, UIC/NIH PBRC PREP, Graduate College
Associate, Graduate College
Instructor, Honors College
Email:
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L@s GANAS (BIOS 294), 1/3/2023 – 5/23/2023
Plant Medicine from Rainforest to Metropolis – A Legacy for the Future (HON 201), 8/22/2022 – 12/2/2022
L@s GANAS (BIOS 294), 1/4/2022 – 5/24/2022
Plant Medicine from Rainforest to Metropolis – A Legacy for the Future (HON 201), 8/23/2021 – 12/6/2021
L@s GANAS (BIOS 294), 1/5/2021 – 5/25/2021
L@s GANAS (BIOS 294), 1/7/2020 – 5/26/2020
L@s GANAS (BIOS 294), 1/8/2019 – 5/28/2019
Selected Grants
UIC Portal to Biomedical Research Careers (UIC PBRC) PREP, National Institutes of Health (National Institute of General Medical Sciences)., 2/1/2024 - 1/31/2029, Obligated Amount: $415994; Anticipated Amount: $2079970
UIC NIH 2024 DEIA Prize Award, National Institutes of Health., 1/8/2024 - 12/31/2025, Obligated Amount: $100000; Anticipated Amount: $100000
Driving Change Learning Grant 2021, Hughes (Howard) Medical Inst., 4/1/2021 - 3/31/2023, Obligated Amount: $60000; Anticipated Amount: $60000
Interventions to Improve Student Success through the American Opportunity Tax Credit at UIC, US General Services Administration., 8/19/2019 - 8/18/2020, Obligated Amount: $1411; Anticipated Amount: $1411
UIC Portal for Biomedical Research Careers (UIC PBRC) PREP, National Institutes of Health (National Institute of General Medical Sciences)., 1/1/2018 - 12/31/2023, Obligated Amount: $1409395; Anticipated Amount: $1512419
HSI STEM Grant: Increasing Latin@s Access to Networks for Advancement in Science, US Department of Education., 10/1/2016 - 9/30/2023, Obligated Amount: $5445211; Anticipated Amount: $5445211
Center for Natural Product Technologies at UIC, National Institutes of Health (National Center for Complementary and Integrative Health)., 9/1/2015 - 6/30/2020, Obligated Amount: $1456875; Anticipated Amount: $1456875
Cyber-Enabled Instrumentation Strategic Planning Workshop, Directorate for Mathematical & Physical Sciences., 4/15/2008 - 3/31/2009, Obligated Amount: $23500; No Anticipated Amount Set
Novel Therapeutics for Bacillus Anthracis, National Institutes of Health (National Institute of Allergy and Infectious Diseases)., 8/15/2003 - 1/31/2009, Obligated Amount: $15456716; Anticipated Amount: $15456716
An Undulator Resource for Structural Biology, National Center for Advancing Translational Sciences., 6/15/2001 - 3/31/2013, Obligated Amount: $28175830; No Anticipated Amount Set
Selected Publications
Alqarni, Saad, Cooper, Laura, Achi, Jazmin Galvan, Bott, Ryan, Sali, Veeresh Kumar, Brown, Andrew, Santarsiero, Bernard D, Krunic, Aleksej, Manicassamy, Balaji, Peet, Norton P, Zhang, Pin, Thatcher, Gregory RJ, Gaisina, Irina N, Rong, Lijun, Moore, Terry W. (2022). Synthesis, Optimization, and Structure–Activity Relationships of Imidazo[1,2‑a]pyrimidines as Inhibitors of Group 2 Influenza A Viruses. Journal of Medicinal Chemistry, 65, (20), 14104-14120. doi:10.1021/acs.jmedchem.2c01329.
Heinz-Kunert, Sherrie L, Pandya, Ashma, Dang, Viet Thuc, Tran, Phuong Nguyen, Ghosh, Sabari, McElheny, Dan, Santarsiero, Bernard D, Ren, Zhong, Nguyen, Andy I. (2022). Assembly of π‑Stacking Helical Peptides into a Porous and Multivariable Proteomimetic Framework. Journal of the American Chemical Society, 144, (15), 7001-7009. doi:10.1021/jacs.2c02146.
Argade, Malaika D, Straub, Carolyn J, Rusali, Lisa E, Santarsiero, Bernard D, Riley, Andrew P. (2021). Synthesis of Aristoquinoline Enantiomers and Their Evaluation at the α3β4 Nicotinic Acetylcholine Receptor. Organic Letters, 23, (20), 7693-7697. doi:10.1021/acs.orglett.1c02057.
Ghosh, Dibbendu, Sinhababu, Soumen, Santarsiero, Bernard D, Mankad, Neal P. (2020). A W/Cu Synthetic Model for the Mo/Cu Cofactor of Aerobic CODH Indicates That Biochemical CO Oxidation Requires a Frustrated Lewis Acid/Base Pair. Journal of the American Chemical Society, 142, (29), 12635-12642. doi:10.1021/jacs.0c03343.
Zhou, Bin, Shetye, Gauri, Yu, Yang, Santarsiero, Bernard D, Klein, Larry L, Abad-Zapatero, Cele, Wolf, Nina M, Cheng, Jinhua, Jin, Yingyu, Lee, Hanki, Suh, Joo-Won, Lee, Hyun, Bisson, Jonathan, McAlpine, James B, Chen, Shao-Nong, Cho, Sang-Hyun, Franzblau, Scott G, Pauli, Guido F. (2020). Antimycobacterial Rufomycin Analogues from Streptomyces atratus Strain MJM3502. Journal of Natural Products, 83, (3), 657-667. doi:10.1021/acs.jnatprod.9b01095.
Wolf, Nina M, Lee, Hyun, Choules, Mary P, Pauli, Guido F, Phansalkar, Rasika, Anderson, Jeffrey R, Gao, Wei, Ren, Jinhong, Santarsiero, Bernard D, Lee, Hanki, Cheng, Jinhua, Jin, Ying-Yu, Ho, Ngoc Anh, Duc, Nguyen Minh, Suh, Joo-Won, Abad-Zapatero, Celerino, Cho, Sanghyun. (2019). High-Resolution Structure of ClpC1-Rufomycin and Ligand Binding Studies Provide a Framework to Design and Optimize Anti-Tuberculosis Leads. ACS Infectious Diseases, 5, (6), 829-840. doi:10.1021/acsinfecdis.8b00276.
Waldhart, Greyson W, Mankad, Neal P, Santarsiero, Bernard D. (2018). Correction to Improvements to Practical Usability of the “Crystalline Sponge” Method for Organic Structure Determination. Organic Letters, 20, (12), 3714-3714. doi:10.1021/acs.orglett.8b01553.
May, Daniel S, Kang, Hahk-Soo, Santarsiero, Bernard D, Krunic, Aleksej, Shen, Qi, Burdette, Joanna E, Swanson, Steven M, Orjala, Jimmy. (2018). Ribocyclophanes A–E, Glycosylated Cyclophanes with Antiproliferative Activity from Two Cultured Terrestrial Cyanobacteria. Journal of Natural Products, 81, (3), 572-578. doi:10.1021/acs.jnatprod.7b00954.
Hevener, Kirk E, Santarsiero, Bernard D, Lee, Hyun, Jones, Jesse A, Boci, Teuta, Johnson, Michael E, Mehboob, Shahila. (2018). Structural characterization of Porphyromonas gingivalis enoyl‐ACP reductase II (FabK). Acta Crystallographica Section F: Structural Biology Communications, 74, (2), 105-112. doi:10.1107/s2053230x18000262.
Education
Degrees:
PhD, University of Washington, United States, 1975
Postgraduate Training:
Myron A Bantrell Research Fellow in Chemical Catalysis, Caltech, United States, 1986
Research Fellow and Lab Director, University of Alberta, Edmonton, Canada, 1991
Visiting Scholar, University of California, Berkeley, United States, 2000
Visiting Investigator, Scripps Research Institute, United States, 2000