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Photo of Birgit M. Dietz

Birgit M. Dietz


Professor, College of Pharmacy - Medicinal Chemistry and Pharmacognosy

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Teaching and Supervision Heading link

Doctoral Research in Pharmacog (PMPG 599), 6/15/2020 – 8/7/2020
Doctoral Research in Pharmacog (PMPG 599), 1/13/2020 – 5/1/2020
Doctoral Research in Pharmacog (PMPG 599), 1/13/2020 – 5/1/2020
PDAT 8: Special Topics (PHAR 508), 8/26/2019 – 12/6/2019
Doctoral Restch in Med Chem (MDCH 599), 8/26/2019 – 12/6/2019
Spec Project Med Chem &Pcog (PMMP 390), 8/26/2019 – 12/6/2019
Doctoral Research in Pharmacog (PMPG 599), 8/26/2019 – 12/6/2019
Pharmacog Research Techniques (PMPG 510), 8/26/2019 – 12/6/2019
Fundamentals of Drug Action (PHAR 422), 8/26/2019 – 12/6/2019

Selected Grants

Sex-differences in Distribution and Bioactivity of Phytoestrogen containing Botanical Dietary Supplements, National Institutes of Health., 7/1/2018 - 6/30/2019, No Obligated Amount Set; No Anticipated Amount Set

Botanical Dietary Supplements for Women's Health, National Institutes of Health (National Center for Complementary and Integrative Health)., 9/1/2015 - 6/30/2022, Obligated Amount: $9708015; Anticipated Amount: $12588944

Botanical Dietary Supplements For Women's Health, National Institutes of Health (National Center for Complementary and Integrative Health)., 9/1/2010 - 8/31/2015, Obligated Amount: $7418005; Anticipated Amount: $7420771

Chemoprevention of Tamoxifen-Induced Endometrial Cancer by Black Cohosh and Red Clover, National Institutes of Health (National Cancer Institute)., 7/1/2010 - 6/30/2012, Obligated Amount: $370909; Anticipated Amount: $370909

Selected Publications

Burton, TCJ, Lankin, DC, Nikolic, D, Guo, B, Ju, J, Dietz, BM, Che, CT, Soejarto, DD, van Breemen, RB. (2021). Isolation and elucidation of two isoflavonoids from an American Indian plant, Amorpha canescens Pursh, using Magnetic Microbead Affinity Selection Screening (MagMASS) for estrogen receptor alpha ligands. Phytochemistry Letters, 45, 110-116. doi:10.1016/j.phytol.2021.07.018.

Malca-Garcia, GR, Liu, Y, Dong, H, Nikolić, D, Friesen, JB, Lankin, DC, McAlpine, J, Chen, SN, Dietz, BM, Pauli, GF. (2021). Auto-hydrolysis of red clover as “green” approach to (iso)flavonoid enriched products. Fitoterapia, 152. doi:10.1016/j.fitote.2021.104878.

Hitzman, RT, Dunlap, TL, Howell, CE, Chen, SN, Vollmer, G, Pauli, GF, Bolton, JL, Dietz, BM. (2020). 6-Prenylnaringenin from Hops Disrupts ERα-Mediated Downregulation of CYP1A1 to Facilitate Estrogen Detoxification. Chemical Research in Toxicology, 33, (11), 2793-2803. doi:10.1021/acs.chemrestox.0c00194.

Mbachu, OC, Howell, C, Simmler, C, Malca Garcia, GR, Skowron, KJ, Dong, H, Ellis, SG, Hitzman, RT, Hajirahimkhan, A, Chen, SN, Nikolic, D, Moore, TW, Vollmer, G, Pauli, GF, Bolton, JL, Dietz, BM. (2020). SAR study on estrogen receptor α/β activity of (Iso)flavonoids: Importance of prenylation, c-ring (un)saturation, and hydroxyl substituents. Journal of Agricultural and Food Chemistry, 68, (39), 10651-10663. doi:10.1021/acs.jafc.0c03526.

Bolton, JL, Dunlap, TL, Hajirahimkhan, A, Mbachu, O, Chen, SN, Chadwick, L, Nikolic, D, Van Breemen, RB, Pauli, GF, Dietz, BM. (2019). Erratum: The multiple biological targets of hops and bioactive compounds (Chemical Research in Toxicology (2019) 32:2 (222-233) DOI: 10.1021/acs.chemrestox.8b00345). Chemical Research in Toxicology, 32, (8), 1732. doi:10.1021/acs.chemrestox.9b00300.

Bolton, JL, Dunlap, TL, Hajirahimkhan, A, Mbachu, O, Chen, SN, Chadwick, L, Nikolic, D, Van Breemen, RB, Pauli, GF, Dietz, BM. (2019). The Multiple Biological Targets of Hops and Bioactive Compounds. Chemical Research in Toxicology, 32, (2), 222-233. doi:10.1021/acs.chemrestox.8b00345.

Wang, S, Dunlap, TL, Huang, L, Liu, Y, Simmler, C, Lantvit, DD, Crosby, J, Howell, CE, Dong, H, Chen, SN, Pauli, GF, Van Breemen, RB, Dietz, BM, Bolton, JL. (2018). Evidence for chemopreventive and resilience activity of licorice: Glycyrrhiza glabra and G. Inflata extracts modulate estrogen metabolism in ACI rats. Cancer Prevention Research, 11, (12), 819-830. doi:10.1158/1940-6207.CAPR-18-0178.

Bolton, JL, Dunlap, TL, Dietz, BM. (2018). Formation and biological targets of botanical o-quinones. Food and Chemical Toxicology, 120, 700-707. doi:10.1016/j.fct.2018.07.050.

Hajirahimkhan, A, Mbachu, O, Simmler, C, Ellis, SG, Dong, H, Nikolic, D, Lankin, DC, Van Breemen, RB, Chen, SN, Pauli, GF, Dietz, BM, Bolton, JL. (2018). Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication. Journal of Natural Products, 81, (4), 966-975. doi:10.1021/acs.jnatprod.7b01070.

Education

Degrees:
PhD, Heinrich Heine University Düsseldorf, Germany, 2002
PharmD, Heinrich Heine University Düsseldorf, Germany, 1997

Postgraduate Training:
Pharmacy Residencies, Hellweg-Pharmacy, Germany, 1997
Pharmacy Residencies, Thiemann, Germany, 1997
Internships, Stadtische Kliniken, Germany, 1993
Internship, Punkt-Pharmacy, Germany, 1992