Photo of Birgit M. Dietz

Birgit M. Dietz


Research Associate Professor, Pharmaceutical Sciences

Contact

Building & Room:

164

Address:

833 S. Wood Street, Chicago, IL, 60612

Office Phone:

(312) 996-2358

Selected Publications

  • Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen S, Nikolic DS, Pauli GF, van Breemen RB, Dietz BM, Bolton JL. Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women’s Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.. Chemical research in toxicology. 2015;28(11):2130-41. doi:10.1021/acs.chemrestox.5b00310.
  • Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen SS, Nikolic DF, Pauli GB, van Breemen RM, Dietz BL, Bolton J. Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women’s Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.. Chemical research in toxicology. 2015;28(11):2130-41. doi:10.1021/acs.chemrestox.5b00310.
  • Dunlap TL, Wang S, Simmler C, Chen S, Pauli GF, Dietz BM, Bolton JL. Differential Effects of Glycyrrhiza Species on Genotoxic Estrogen Metabolism: Licochalcone A Downregulates P450 1B1, whereas Isoliquiritigenin Stimulates It.. Chemical research in toxicology. 2015;28(8):1584-94. doi:10.1021/acs.chemrestox.5b00157.
  • Dunlap TL, Wang S, Simmler C, Chen S, Pauli GF, Dietz BM, Bolton JL. Differential Effects of Glycyrrhiza Species on Genotoxic Estrogen Metabolism: Licochalcone A Downregulates P450 1B1, whereas Isoliquiritigenin Stimulates It.. Chemical research in toxicology. 2015;28(8):1584-94. doi:10.1021/acs.chemrestox.5b00157.
  • van Breemen RB, Yuan YP, Banuvar SF, Shulman L, Qiu XM, Alvarenga RL, Chen SF, Dietz BC, Bolton JS, Pauli G, Krause E, Viana M, Nikolic D. Pharmacokinetics of prenylated hop phenols in women following oral administration of a standardized extract of hops.. Molecular nutrition & food research. 2014;58(10):1962-9. doi:10.1002/mnfr.201400245.
  • Krause EC, Yuan Y, Hajirahimkhan A, Dong HM, Dietz BS, Nikolic DF, Pauli GL, Bolton JB, van Breemen R. Biological and chemical standardization of a hop (Humulus lupulus) botanical dietary supplement.. Biomedical chromatography : BMC. 2014;28(6):729-34. doi:10.1002/bmc.3177.
  • Hajirahimkhan A, Simmler C, Yuan YR, Anderson J, Chen SS, Nikolic DM, Dietz BF, Pauli GB, van Breemen RL, Bolton J. Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms.. PloS one. 2013;8(7):e67947. doi:10.1371/journal.pone.0067947.
  • Hajirahimkhan A, Simmler C, Yuan YR, Anderson J, Chen SM, Nikolić DF, Dietz BB, Pauli GL, van Breemen R, Bolton J. Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms.. PloS one. 2013;8(7):e67947. doi:10.1371/journal.pone.0067947.
  • Dietz BM, Hagos GK, Eskra JN, Wijewickrama GT, Anderson JR, Nikolic DS, Guo JJ, Wright B, Chen SF, Pauli GB, van Breemen RL, Bolton J. Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo.. Molecular nutrition & food research. 2013;57(6):1055-66. doi:10.1002/mnfr.201200534.
  • Hajirahimkhan A, Dietz BM, Bolton JL. Botanical modulation of menopausal symptoms: mechanisms of action?. Planta medica. 2013;79(7):538-53. doi:10.1055/s-0032-1328187.
  • Snelten CS, Dietz BM, Bolton JL. Modulation of Estrogen Chemical Carcinogenesis by Botanical Supplements used for Postmenopausal Women’s Health.. Drug discovery today. Disease mechanisms. 2012;9(1). doi:10.1016/j.ddmec.2012.11.001.
  • Hemachandra LP, Madhubhani P, Chandrasena RC, Esala PA, Chen SM, Main MF, Lankin DR, Scism RL, Dietz B, Pauli G, Thatcher G, Bolton J. Hops (Humulus lupulus) inhibits oxidative estrogen metabolism and estrogen-induced malignant transformation in human mammary epithelial cells (MCF-10A).. Cancer prevention research (Philadelphia, Pa.). 2012;5(1):73-81. doi:10.1158/1940-6207.CAPR-11-0348.
  • Gödecke TG, Yao PM, Napolitano JL, Nikolić DB, Dietz BR, Bolton J, van Breemen RC, Farnsworth NF, Chen S, Lankin D, Pauli G. Integrated standardization concept for Angelica botanicals using quantitative NMR.. Fitoterapia. 2012;83(1):18-32. doi:10.1016/j.fitote.2011.08.017.
  • Dietz BM, Bolton JL. Biological reactive intermediates (BRIs) formed from botanical dietary supplements.. Chemico-biological interactions. 2011;192(1-2):72-80. doi:10.1016/j.cbi.2010.10.007.
  • Wang Z, Wijewickrama GT, Peng KW, Dietz BM, Yuan LB, van Breemen RL, Bolton JR, Thatcher G. Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus.. The Journal of biological chemistry. 2009;284(13):8633-42. doi:10.1074/jbc.M807860200.
  • Gödecke TS, Nikolic DC, Lankin D, Chen SL, Powell SM, Dietz BL, Bolton JB, van Breemen RR, Farnsworth NF, Pauli G. Phytochemistry of cimicifugic acids and associated bases in Cimicifuga racemosa root extracts.. Phytochemical analysis : PCA. 2009;20(2):120-33. doi:10.1002/pca.1106.
  • Powell SL, Gödecke TS, Nikolic D, Chen SM, Ahn SR, Dietz BB, Farnsworth NC, van Breemen RF, Lankin DL, Pauli G, Bolton J. In vitro serotonergic activity of black cohosh and identification of N(omega)-methylserotonin as a potential active constituent.. Journal of agricultural and food chemistry. 2008;56(24):11718-26. doi:10.1021/jf803298z.
  • Dietz BM, Liu DK, Hagos GM, Yao PR, Schinkovitz AF, Pro SB, Deng SL, Farnsworth N, Pauli G, van Breemen R, Bolton J. Angelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: quinone oxidoreductase 1 by alkylating Keap1.. Chemical research in toxicology. 2008;21(10):1939-48. doi:10.1021/tx8001274.
  • Yu BM, Dietz BL, Dunlap TD, Kastrati IR, Lantvit DL, Overk CR, Yao P, Qin Z, Bolton J, Thatcher G. Structural modulation of reactivity/activity in design of improved benzothiophene selective estrogen receptor modulators: induction of chemopreventive mechanisms.. Molecular cancer therapeutics. 2007;6(9):2418-28. doi:10.1158/1535-7163.MCT-07-0268.
  • Dietz BM, Bolton JL. Botanical dietary supplements gone bad.. Chemical research in toxicology. 2007;20(4):586-90. doi:10.1021/tx7000527.
  • Gafner SM, Dietz BL, McPhail KM, Scott IA, Glinski JE, Russell FM, McCollom MW, Budzinski JC, Foster BR, Bergeron CL, Rhyu M, Bolton J. Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro.. Journal of natural products. 2006;69(3):432-5. doi:10.1021/np058114h.
  • Liu GL, Eggler AM, Dietz BD, Mesecar AL, Bolton JM, Pezzuto JB, van Breemen R. Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1.. Analytical chemistry. 2005;77(19):6407-14. doi:10.1021/ac050892r.
  • Dietz BM, Kang YH, Liu GL, Eggler AR, Yao PF, Chadwick LR, Pauli GD, Farnsworth NB, Mesecar AL, van Breemen R, Bolton J. Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase.. Chemical research in toxicology. 2005;18(8):1296-305. doi:10.1021/tx050058x.