Photo of Birgit Ursula Jaki

Birgit Ursula Jaki

Research Associate Professor, Medicinal Chemistry and Pharmacognosy
INST AFFL, Institute for Tuberculosis Research


Building & Room:



833 S. Wood Street, Chicago, IL, 60612

Office Phone:

(312) 355-4276


Selected Publications

  • Gao WY, Kim J, Chen S, Cho SU, Choi JY, Jaki BC, Jin YE, Lankin DY, Lee JG, Lee SG, Napolitano JW, Franzblau SF, Suh J, Pauli G. Discovery and characterization of the tuberculosis drug lead ecumicin.. Organic letters. 2014;16(23):6044-7. doi:10.1021/ol5026603.
  • Pauli GF, Chen S, Simmler C, Lankin DC, Gödecke TU, Jaki BB, Friesen JB, McAlpine JG, Napolitano J. Importance of purity evaluation and the potential of quantitative ¹H NMR as a purity assay.. Journal of medicinal chemistry. 2014;57(22):9220-31. doi:10.1021/jm500734a.
  • Ramos Alvarenga RF, Wan B, Inui TG, Franzblau SF, Pauli GU, Jaki B. Airborne antituberculosis activity of Eucalyptus citriodora essential oil.. Journal of natural products. 2014;77(3):603-10. doi:10.1021/np400872m.
  • Cai GG, Napolitano JU, Wang YW, Jaki BH, Suh JA, Yang SG, Lee IF, Franzblau S, Pauli G, Cho S. Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain.. Journal of natural products. 2013;76(11):2009-18. doi:10.1021/np400145u.
  • Hwang CH, Jaki BU, Klein L, Lankin DC, Napolitano JG, Fryling NA, Franzblau SG, Cho S, Stamets PE, Wang YF, Pauli G. Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis.. Journal of natural products. 2013;76(10):1916-22. doi:10.1021/np400497f.
  • Cai GF, Pauli GU, Wang YG, Jaki B, Franzblau S. Rapid determination of growth inhibition of Mycobacterium tuberculosis by GC-MS/MS quantitation of tuberculostearic acid.. Tuberculosis (Edinburgh, Scotland). 2013;93(3):322-9. doi:10.1016/
  • Qiu FU, Cai GC, Jaki BG, Lankin DF, Franzblau S, Pauli G. Quantitative purity-activity relationships of natural products: the case of anti-tuberculosis active triterpenes from Oplopanax horridus.. Journal of natural products. 2013;76(3):413-9. doi:10.1021/np3007809.
  • Jaki BU, Franzblau SG, Chadwick LR, Lankin DC, Zhang FF, Wang Y, Pauli G. Purity-activity relationships of natural products: the case of anti-TB active ursolic acid.. Journal of natural products. 2008;71(10):1742-8. doi:10.1021/np800329j.
  • Chen S, Turner AU, Jaki BS, Nikolic DB, van Breemen RF, Pauli G. An experimental implementation of chemical subtraction.. Journal of pharmaceutical and biomedical analysis. 2008;46(4):692-8. doi:10.1016/j.jpba.2007.12.014.
  • Jaki BU, Franzblau SG, Cho S, Pauli GF. Development of an extraction method for mycobacterial metabolome analysis.. Journal of pharmaceutical and biomedical analysis. 2006;41(1):196-200. doi:10.1016/j.jpba.2005.10.022.
  • Nikolic DS, Lankin DC, Chen S, Jaki BU, Krunic A, van Breemen RB, Fong HH, Farnsworth NR, Pauli GF. Cimipronidine, a cyclic guanidine alkaloid from Cimicifuga racemosa.. Journal of natural products. 2005;68(8):1266-70. doi:10.1021/np050066d.