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Photo of Brian T. Murphy

Brian T. Murphy

Professor, College of Pharmacy - Pharmaceutical Sciences

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Teaching and Supervision Heading link

PSCI 423, 1/8/2024 – Present
Science Writing (PSCI 504), 1/8/2024 – 3/1/2024
PSCI Ph.D. Thesis Research (PSCI 599), 1/8/2024 – 4/26/2024
Doctoral Research in Pharmacog (PMPG 599), 1/8/2024 – 4/26/2024
Adv Pharmacognosy (PSCI 522), 1/8/2024 – 4/26/2024
Doctoral Research in Pharmacog (PMPG 599), 8/21/2023 – 12/1/2023
PSCI Ph.D. Thesis Research (PSCI 599), 8/21/2023 – 12/1/2023
PSCI Ph.D. Thesis Research (PSCI 599), 6/12/2023 – 8/4/2023
Biomedicinal Chemistry – PSCI 423 (PSCI 423), 2/2023 – Present

Selected Grants

Preparation for Research in Space Microbiology (PRISM), US NASA Jet Propulsion Laboratory., 3/27/2024 - 9/3/2024, Obligated Amount: $18000; Anticipated Amount: $18000

Botanical derived progestins and their impact on women's health, National Institutes of Health (National Center for Complementary and Integrative Health)., 5/1/2023 - 2/29/2028, Obligated Amount: $759525; Anticipated Amount: $1998750

Discovery of a pigment produced by Streptococcus pyogenes, National Institutes of Health (National Institute of Allergy and Infectious Diseases)., 3/1/2023 - 2/28/2025, Obligated Amount: $193496; Anticipated Amount: $423776

Partnering with Community Centers to Perform 'Environment-to-Bioassay' Antbiotic Discovery, Purdue University., 6/1/2022 - 9/30/2023, Obligated Amount: $8970; Anticipated Amount: $8970

Illinois-Indiana Sea Grant 2022-2023 Omnibus (Parent Record), Purdue University., 2/1/2022 - 6/30/2024, Obligated Amount: $207175; Anticipated Amount: $207175

Establishing two new bacterial phyla to produce the next generation of biomedical drug leads,�, Chicago Biomedical Consortium., 10/1/2021 - 9/30/2024, Obligated Amount: $125000; Anticipated Amount: $125000

Identification of antimicrobial reagents against TB and ESKAPE pathogens from bacteria collected in Vietnam�., Vietnam Academy of Science & Technology (Inst of Marine Biochemistry)., 5/5/2021 - 4/30/2023, Obligated Amount: $39975; Anticipated Amount: $39975

Development of a bacterial host for natural product discovery and production, National Institutes of Health (National Institute of General Medical Sciences)., 9/20/2020 - 6/30/2025, Obligated Amount: $1532645; Anticipated Amount: $1532645

A new paradigm for the creation and mining of microbial libraries for drug discovery, National Institutes of Health (National Institute of General Medical Sciences)., 8/10/2018 - 7/31/2023, Obligated Amount: $2069671; Anticipated Amount: $2069671

Selected Publications

Caro-Diaz, Eduardo J, Balunas, Marcy J, Giddings, Lesley-Ann, Loesgen, Sandra, Murphy, Brian T, Naman, C Benjamin, Salomon, Christine E, Tidgewell, Kevin J, Winter, Jaclyn M. (2024). Outlining the Hidden Curriculum: Perspectives on Successfully Navigating Scientific Conferences. Journal of Natural Products. doi:10.1021/acs.jnatprod.3c00867.

Nepomuceno, Vanessa M, Tylor, Kaitlyn M, Carlson, Skylar, Federle, Michael J, Murphy, Brian T, Morales, Tiara Perez. (2023). A Streptomyces tendae Specialized Metabolite Inhibits Quorum Sensing in Group A Streptococcus. Microbiology Spectrum, 11, (4), e05279-e05222. doi:10.1128/spectrum.05279-22.

Lee, Jung-Ho, Ma, Rui, Nguyen, Linh, Khan, Shahebraj, Qader, Mallique, Mpofu, Enock, Shetye, Gauri, Krull, Nyssa K, Augustinović, Mario, Omarsdottir, Sesselja, Cho, Sanghyun, Franzblau, Scott G, Murphy, Brian T. (2023). Discovery of a New Antibiotic Demethoxytetronasin Using a Dual-Sided Agar Plate Assay (DAPA). ACS Infectious Diseases, 9, (8), 1593-1601. doi:10.1021/acsinfecdis.3c00171.

Nguyen, Thi Hoang Anh, Quynh, Thi, Nguyen, Thuy Linh, Le Thi, Hong Minh, Nguyen, Mai Anh, Murphy, Brian T, Dam, Thanh Xuan, Huong, Doan Thi Mai, Van Cuong, Pham. (2023). New Sesterterpenoid from the Marine Fungus Penicillium oxalicum M893. Natural Product Communications, 18, (8), 1934578×231191636. doi:10.1177/1934578×231191636.

Clark, Chase M, Hernandez, Antonio, Mullowney, Michael W, Fitz-Henley, Jhewelle, Li, Emma, Romanowski, Sean B, Pronzato, Roberto, Manconi, Renata, Sanchez, Laura M, Murphy, Brian T. (2022). Relationship between bacterial phylotype and specialized metabolite production in the culturable microbiome of two freshwater sponges. ISME Communications, 2, (1), 22. doi:10.1038/s43705-022-00105-8.

Corona‐Avila, Irene, Lee, Jeongho, Hernandez, Antonio, Krull, Nyssa, Augustinovic, Mario, Jones, Derick, Ndekwe, Tatyana, Murphy, Brian T. (2022). Isolation and Characterization of Antimicrobials from Icelandic Aquatic Bacteria. The FASEB Journal, 36, (S1). doi:10.1096/fasebj.2022.36.s1.0r442.

Li, Kailiang, Diakite, Djeneba, Austin, Julia, Lee, Jung-Ho, Lantvit, Daniel D, Murphy, Brian T, Burdette, Joanna E. (2022). The Flavonoid Baicalein Negatively Regulates Progesterone Target Genes in the Uterus in Vivo. Journal of Natural Products, 85, (1), 237-247. doi:10.1021/acs.jnatprod.1c01008.

Austin, Julia R, Li, Kailiang, Rodríguez, Rocío Rivera, Lantvit, Daniel D, Murphy, Brian T, Burdette, Joanna E. (2021). Irilone, a Red Clover Isoflavone, Combined with Progesterone Enhances PR Signaling through the Estrogen and Glucocorticoid Receptors. Journal of Natural Products, 84, (12), 3090-3099. doi:10.1021/acs.jnatprod.1c00835.

Elfeki, Maryam, Mantri, Shrikant, Clark, Chase M, Green, Stefan J, Ziemert, Nadine, Murphy, Brian T. (2021). Evaluating the Distribution of Bacterial Natural Product Biosynthetic Genes across Lake Huron Sediment. ACS Chemical Biology, 16, (11), 2623-2631. doi:10.1021/acschembio.1c00653.

Professional Leadership

Executive Committee, American Society of Pharmacognosy, 1/1/2021 - Present

Executive Committee, American Society of Pharmacognosy, 1/1/2021 - Present

Diversity & Inclusion Committee, American Society of Pharmacognosy, 1/1/2021 - Present

NIH NCCIH Training and Education Review Panel, 3/20/2020 - Present

ASP Diversity and Inclusion Committee, 1/2018 - 12/2023

Notable Honors

2023, American Society for Microbiology Distinguished Lecturer, American Society for Microbiology

2022, UIC Global Engagement Faculty Award, University of Illinois Chicago

2020, Teacher of the Semester Award, Pharmacy P1 Class of 2023


PhD, Virginia Polytechnic Institute, United States, 2007
MS, University of Massachusetts Dartmouth, United States, 2003
BS, University of Massachusetts Dartmouth, United States, 2002