Brian T. Murphy
Professor, College of Pharmacy - Pharmaceutical Sciences
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About
Teaching and Supervision
PSCI Ph.D. Thesis Research (PSCI 599), 1/13/2025 – 5/2/2025
Doctoral Research in Pharmacog (PMPG 599), 1/13/2025 – 5/2/2025
Science Writing (PSCI 504), 1/13/2025 – 3/7/2025
Undergrad Res Exp Pharm Sci (PSCI 300), 1/13/2025 – 5/2/2025
PSCI Ph.D. Thesis Research (PSCI 599), 8/26/2024 – 12/6/2024
Doctoral Research in Pharmacog (PMPG 599), 8/26/2024 – 12/6/2024
Undergrad Res Exp Pharm Sci (PSCI 300), 8/26/2024 – 12/6/2024
Doctoral Research in Pharmacog (PMPG 599), 6/10/2024 – 8/2/2024
Science Writing (PSCI 504), 1/8/2024 – 3/1/2024
Selected Grants
Preparation for Research in Space Microbiology (PRISM), US NASA Jet Propulsion Laboratory., 3/27/2024 - 9/3/2024, Obligated Amount: $18000; Anticipated Amount: $18000
Botanical derived progestins and their impact on women's health, National Institutes of Health (National Center for Complementary and Integrative Health)., 5/1/2023 - 2/29/2028, Obligated Amount: $1151280; Anticipated Amount: $1998750
Discovery of a pigment produced by Streptococcus pyogenes, National Institutes of Health (National Institute of Allergy and Infectious Diseases)., 3/1/2023 - 2/28/2026, Obligated Amount: $423776; Anticipated Amount: $423776
Partnering with Community Centers to Perform 'Environment-to-Bioassay' Antbiotic Discovery, Purdue University., 6/1/2022 - 9/30/2023, Obligated Amount: $8970; Anticipated Amount: $8970
Illinois-Indiana Sea Grant 2022-2023 Omnibus (Parent Record), Purdue University., 2/1/2022 - 4/30/2025, Obligated Amount: $207175; Anticipated Amount: $207175
Establishing two new bacterial phyla to produce the next generation of biomedical drug leads,�, Chicago Biomedical Consortium., 10/1/2021 - 9/30/2024, Obligated Amount: $125000; Anticipated Amount: $125000
Identification of antimicrobial reagents against TB and ESKAPE pathogens from bacteria collected in Vietnam�., Vietnam Academy of Science & Technology (Inst of Marine Biochemistry)., 5/5/2021 - 4/30/2025, Obligated Amount: $39975; Anticipated Amount: $39975
Development of a bacterial host for natural product discovery and production, National Institutes of Health (National Institute of General Medical Sciences)., 9/20/2020 - 6/30/2025, Obligated Amount: $1532645; Anticipated Amount: $1532645
A new paradigm for the creation and mining of microbial libraries for drug discovery, National Institutes of Health (National Institute of General Medical Sciences)., 8/10/2018 - 7/31/2023, Obligated Amount: $2069671; Anticipated Amount: $2069671
Selected Publications
Hernandez, Antonio, Krull, Nyssa K, Murphy, Brian T. (2025). Use of MALDI-TOF mass spectrometry and IDBac to mine for understudied bacterial genera from the environment. ISME Communications, 5, (1), ycaf046. doi:10.1093/ismeco/ycaf046.
Quynh, Thi, Van Trinh, Thi Thanh, Phi, Thi Dao, Nguyen, Thuy Linh, Vu, Thi Quyen, Le, Thi Hong Minh, Murphy, Brian T, Doan, Thi Mai Huong, Pham, Van Cuong. (2024). New Shikimic Acid Derivatives From the Marine‐Derived Actinomycete Streptomyces sp. G666 and Their Antimicrobial Activities. Chemistry & Biodiversity, e202402701. doi:10.1002/cbdv.202402701.
Tan, Jin Yi, Augustinović, Mario, Omar, Ashraf M, Lourenzon, Vitor B, Krull, Nyssa, Lopez, Xochitl, Khin, Manead, Shetye, Gauri, Nguyen, Duc, Qader, Mallique, Nugent, Angela C, Mpofu, Enock, Williams, Camarria, Rodriguez, Jonathon, Burdette, Joanna E, Cho, Sanghyun, Franzblau, Scott G, Eustáquio, Alessandra S, Zhang, Qibin, Murphy, Brian T. (2024). Discovery of New Cyclic Lipodepsipeptide Orfamide N via Partnership with Middle School Students from the Boys and Girls Club. ACS Omega, 9, (44), 44749-44759. doi:10.1021/acsomega.4c07459.
Paulo, Bruno S, Recchia, Michael JJ, Lee, Sanghoon, Fergusson, Claire H, Romanowski, Sean B, Hernandez, Antonio, Krull, Nyssa, Liu, Dennis Y, Cavanagh, Hannah, Bos, Allyson, Gray, Christopher A, Murphy, Brian T, Linington, Roger G, Eustaquio, Alessandra S. (2024). Discovery of megapolipeptins by genome mining of a Burkholderiales bacteria collection. Chemical Science, 15, (40), 16567-16581. doi:10.1039/d4sc03594a.
Caro-Diaz, Eduardo J, Balunas, Marcy J, Giddings, Lesley-Ann, Loesgen, Sandra, Murphy, Brian T, Naman, C Benjamin, Salomon, Christine E, Tidgewell, Kevin J, Winter, Jaclyn M. (2024). Outlining the Hidden Curriculum: Perspectives on Successfully Navigating Scientific Conferences. Journal of Natural Products, 87, (5), 1487-1492. doi:10.1021/acs.jnatprod.3c00867.
Nepomuceno, Vanessa M, Tylor, Kaitlyn M, Carlson, Skylar, Federle, Michael J, Murphy, Brian T, Morales, Tiara Perez. (2023). A Streptomyces tendae Specialized Metabolite Inhibits Quorum Sensing in Group A Streptococcus. Microbiology Spectrum, 11, (4), e05279-e05222. doi:10.1128/spectrum.05279-22.
Lee, Jung-Ho, Ma, Rui, Nguyen, Linh, Khan, Shahebraj, Qader, Mallique, Mpofu, Enock, Shetye, Gauri, Krull, Nyssa K, Augustinović, Mario, Omarsdottir, Sesselja, Cho, Sanghyun, Franzblau, Scott G, Murphy, Brian T. (2023). Discovery of a New Antibiotic Demethoxytetronasin Using a Dual-Sided Agar Plate Assay (DAPA). ACS Infectious Diseases, 9, (8), 1593-1601. doi:10.1021/acsinfecdis.3c00171.
Nguyen, Thi Hoang Anh, Quynh, Thi, Nguyen, Thuy Linh, Le Thi, Hong Minh, Nguyen, Mai Anh, Murphy, Brian T, Dam, Thanh Xuan, Huong, Doan Thi Mai, Van Cuong, Pham. (2023). New Sesterterpenoid from the Marine Fungus Penicillium oxalicum M893. Natural Product Communications, 18, (8), 1934578×231191636. doi:10.1177/1934578×231191636.
Clark, Chase M, Hernandez, Antonio, Mullowney, Michael W, Fitz-Henley, Jhewelle, Li, Emma, Romanowski, Sean B, Pronzato, Roberto, Manconi, Renata, Sanchez, Laura M, Murphy, Brian T. (2022). Relationship between bacterial phylotype and specialized metabolite production in the culturable microbiome of two freshwater sponges. ISME Communications, 2, (1), 22. doi:10.1038/s43705-022-00105-8.
Professional Leadership
Executive Committee, American Society of Pharmacognosy, 1/1/2021 - Present
Executive Committee, American Society of Pharmacognosy, 1/1/2021 - Present
Diversity & Inclusion Committee, American Society of Pharmacognosy, 1/1/2021 - Present
NIH NCCIH Training and Education Review Panel, 3/20/2020 - Present
ASP Diversity and Inclusion Committee, 1/2018 - 12/2023
Notable Honors
2023, American Society for Microbiology Distinguished Lecturer, American Society for Microbiology
2022, UIC Global Engagement Faculty Award, University of Illinois Chicago
2020, Teacher of the Semester Award, Pharmacy P1 Class of 2023
Education
Degrees:
PhD, Virginia Polytechnic Institute, United States, 2007
MS, University of Massachusetts Dartmouth, United States, 2003
BS, University of Massachusetts Dartmouth, United States, 2002