Zackery P. Bulman
Director, Infectious Diseases Pharmacology Fellowship, Pharmacy Practice
Associate Professor, University of Illinois at Chicago
Department Affiliate, Pharmaceutical Sciences
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About
Research Interests:
The medical community is at a constant state of war with bacteria to both prevent and overcome antimicrobial resistance, which is one of the largest threats to global health. The frequency and nature of bacterial cell replication combined with the widespread use of antibiotics suggests that antimicrobial resistance is likely to persist. Dr. Bulman’s laboratory investigates novel pharmacotherapeutic approaches that aim to overcome drug resistant bacteria and improve patient outcomes.
Teaching and Supervision
Applied Research Methods (PMPR 45457), 1/12/2026 – 5/1/2026
Undergrad Res Exp Pharm Pract (PMPR 47298), 1/12/2026 – 5/1/2026
Concentration Research (PMPR 485), 8/25/2025 – 12/5/2025
Pharmacokinetics (PHAR 435), 8/25/2025 – 12/5/2025
Pharmacokinetics (PHAR 435), 8/25/2025 – 12/5/2025
Undergrad Resrch Pharm Pract (PMPR 380), 8/25/2025 – 12/5/2025
Undergrad Resrch Pharm Pract (PMPR 380), 1/13/2025 – 5/2/2025
Undergrad Res Exp Pharm Pract (PMPR 300), 1/13/2025 – 5/2/2025
Applied Research Methods (PMPR 376), 1/13/2025 – 5/2/2025
Selected Grants
Pharmacodynamic activity of imipenem-relebactam against Mycobacterium abscessus in time-kill assays and the hollow fiber infection model, Merck & Co Inc., 11/6/2024 - 11/5/2025, Obligated Amount: $168760.2; Anticipated Amount: $168760.2
Precise Combination Strategies Targeting Carbapenem-Resistant Klebsiella pneumoniae, National Institutes of Health (National Institute of Allergy and Infectious Diseases)., 12/5/2022 - 11/30/2027, Obligated Amount: $2992945; Anticipated Amount: $3660946
Selected Publications
Karaba, Sara M, Hareza, Dariusz A, Munita, Jose M, Martinez, Jose RW, Bergman, Yehudit, Hawes, Armani M, Bulman, Zackery P, Cosgrove, Sara E, Simner, Patricia J, Tamma, Pranita D. (2026). Comparative outcomes of ceftazidime-avibactam versus meropenem-vaborbactam for KPC-producing Enterobacterales infections. Antimicrobial Agents and Chemotherapy, 70, (5), e01602-e01625. doi:10.1128/aac.01602-25.
Ozer, Egon A, Nozick, Sophie H, Singh, Nidhi, Watkins, Jackson V, Hauser, Alan R, Bulman, Zackery P. (2026). Complete genome sequences of KPC-producing Klebsiella pneumoniae isolates pre- and post-development of meropenem/vaborbactam resistance. Microbiology Resource Announcements, 15, (4), e01447-e01425. doi:10.1128/mra.01447-25.
Singh, Nidhi, Jogan, Christin ML, Zang, Yanan, Shan, Xindi, Lang, Yinzhi, Karunanidhi, Arunkumar, Watkins, Jackson V, Curry, Brooke N, Tamma, Pranita D, Nozick, Sophie H, Ozer, Egon A, Hauser, Alan R, Bulitta, Jürgen B, Bulman, Zackery P. (2026). Aminoglycosides enhance meropenem/vaborbactam activity against KPC-producing Klebsiella pneumoniae in the hollow fiber infection model. Antimicrobial Agents and Chemotherapy, 70, (4), e01365-e01325. doi:10.1128/aac.01365-25.
Karunanidhi, Arunkumar, Singh, Nidhi, Watkins, Jackson V, Smith, Nicholas M, Zang, Yanan, Shan, Xindi, Espinoza, Gilberto, Li, Jian, Lang, Yinzhi, Bulitta, Jürgen B, Bulman, Zackery P. (2026). Ceftazidime/avibactam and aztreonam combined with an aminoglycoside combat metallo-β-lactamase-producing Klebsiella pneumoniae. Antimicrobial Agents and Chemotherapy, 70, (3), e01540-e01525. doi:10.1128/aac.01540-25.
Nguyen, Minh-Vu H, Plattner, Michel, Verma, Deepshikha, Krishnamurthy, Ramya V, Xie, Min, de Moura, Vinicius Calado Nogueira, Haldimann, Klara, Lang, Ramon, Becker, Katja, Kaur, Parvinder, Shandil, Radha Krishan, Singh, Mayas, Bulman, Zackery P, Dick, Thomas, Narayanan, Shridhar, Schulthess, Bettina, Mitarai, Satoshi, Daley, Charles L, Hobbie, Sven N. (2026). Multicentre preclinical profiling of apramycin for the treatment of nontuberculous mycobacteria. EBioMedicine, 123, 106103. doi:10.1016/j.ebiom.2025.106103.
Curry, Brooke N, Singh, Nidhi, Gross, Alan E, Watkins, Jackson V, Ozer, Egon A, Karunanidhi, Arunkumar, Sherwood, Kayley, Obanor, Osayamen, Ismail, Nahed, Hauser, Alan R, Bulman, Zackery P. (2025). Pharmacodynamic insights to support pneumonia treatment in a patient co-infected with two carbapenem-resistant bacteria. International Journal of Antimicrobial Agents, 66, (6), 107633. doi:10.1016/j.ijantimicag.2025.107633.
Singh, Nidhi, Dangi, Bikash, Johnson, Jeremy J, Louie, Arnold, Karunanidhi, Arunkumar, Curry, Brooke N, Mitarai, Satoshi, Daley, Charles L, Hobbie, Sven N, Bulman, Zackery P. (2025). Pharmacodynamic assessment of apramycin against Mycobacterium abscessus in a hollow fibre infection model. Journal of Antimicrobial Chemotherapy, 80, (5), 1309-1314. doi:10.1093/jac/dkaf073.
Bulman, Zackery P, Cao, Lishan, Curry, Brooke N, Biagi, Mark, Vivo, Amanda, Suda, Katie J, Evans, Charlesnika T. (2024). Ceftazidime/avibactam alone or in combination with an aminoglycoside for treatment of carbapenem-resistant Enterobacterales infections: A retrospective cohort study. International Journal of Antimicrobial Agents, 64, (5), 107321. doi:10.1016/j.ijantimicag.2024.107321.
Shin, Eunjeong, Zhang, Yongzhen, Zhou, Jieqiang, Lang, Yinzhi, Sayed, Alaa RM, Werkman, Carolin, Jiao, Yuanyuan, Kumaraswamy, Monika, Bulman, Zackery P, Luna, Brian M, Bulitta, Jürgen B. (2024). Improved characterization of aminoglycoside penetration into human lung epithelial lining fluid via population pharmacokinetics. Antimicrobial Agents and Chemotherapy, 68, (2), e01393-e01323. doi:10.1128/aac.01393-23.
Professional Leadership
AST Breakpoints Working Group Member, Clinical and Laboratory Standards Institute, 1/1/2025 - Present
SIDP Website Committee, Society for Infectious Diseases Pharmacists, 11/1/2023 - 10/31/2024
SIDP Website Committee, Society for Infectious Diseases Pharmacists, 11/1/2022 - 10/31/2023
ISAC Anti-Infective Pharmacology Working Group, 12/2/2019 - Present
ISAP Treasurer, International Society of Anti-Infective Pharmacology, 2018 - Present
Notable Honors
2024, Investigator of the Year Award, University of Illinois Chicago Retzky College of Pharmacy
2023, New Investigator Award, American College of Clinical Pharmacy
2023, Early Career Investigator Award, Society of Infectious Diseases Pharmacists (SIDP)
2023, UIC Researcher of the Year- Rising Star Award in Clinical Sciences, University of Illinois at Chicago
2020, FISAC, International Society of Antimicrobial Chemotherapy
2020, Hans W. Vahlteich Research Scholar,
Education
Degrees:
PharmD, University at Buffalo, State University of New York, United States, 2015
B.S., Rochester Institute of Technology, United States, 2011
Postgraduate Training:
Infectious Diseases Pharmacology Fellowship, University at Buffalo, State University of New York, United States, 2017
Clinical and Translational Research Fellow, VA Western New York Healthcare System, United States, 2017