Chun-Tao Che
Harry H.S. Fong Professor of Pharmacognosy, College of Pharmacy
Director, WHO Collaborating Center for Traditional Medicine
Contact
Address:
833 South Wood St, Chicago, Illinois
Office Phone:
Email:
Related Sites:
About Heading link
Research Interests:
Drug lead discovery from medicinal plants; Traditional Chinese medicine; Quality and standardization of botanical supplements
Teaching and Supervision Heading link
Doctoral Restch in Med Chem (MDCH 599), 8/22/2022 – 12/2/2022
Doctoral Research in Pharmacog (PMPG 599), 8/22/2022 – 12/2/2022
PhLAMES 5 (PHAR 469), 8/22/2022 – 12/2/2022
Undergrad Res Pharm Sci (PSCI 380), 8/22/2022 – 12/2/2022
PhLAMES 6 (PHAR 470), 1/10/2022 – 4/29/2022
Doctoral Research in Pharmacog (PMPG 599), 1/10/2022 – 4/29/2022
Doctoral Research in Pharmacog (PMPG 599), 8/23/2021 – 12/3/2021
PhLAMES 5 (PHAR 469), 8/23/2021 – 12/3/2021
Doctoral Research in Pharmacog (PMPG 599), 1/11/2021 – 4/30/2021
Selected Grants
Medicinal Plants of Laos: Discoveries, Conservation, and Community Engagement: Phase II, California Community Foundation., 7/1/2019 - 6/30/2023, Obligated Amount: $219090; Anticipated Amount: $219090
Medicinal Plants of Laos: Discoveries, Conservation, and Community Engagement: Phase II, California Community Foundation., 7/1/2019 - 6/30/2023, Obligated Amount: $219090; Anticipated Amount: $219090
Defining the role of isoprenylated xanthones from the mangosteen for enhancing degradation of full length and variant forms of androgen receptor in prostate cancer, National Institutes of Health (National Cancer Institute)., 1/1/2019 - 12/31/2023, Obligated Amount: $1411701; Anticipated Amount: $1765131
Rosemary as a Food Preservative: Implications for Gastrointestinal Health, US Department of Agriculture (National Institute of Food and Agriculture)., 1/1/2017 - 4/14/2022, Obligated Amount: $470000; Anticipated Amount: $470000
California Community Foundation (CCF) Elina Vesara Ostern Fund, California Community Foundation., 7/1/2013 - 12/31/2014, Obligated Amount: $53804; Anticipated Amount: $53804
Technical Development of a Herb-based Topical Application for Psoriasis Treatment, Innovation and Technology Commission., 4/1/2007 - 9/30/2008, Obligated Amount: $140341; No Anticipated Amount Set
Selected Publications
Zia-ur-Rehman, HM, Rasheed, K, Bashir, A, Gurgul, F, Wahid, CT, Che, I, Shahzadi, T, Khan, . (2022). UHPLC-MS/MS-GNPS based phytochemical investigation of Dryopteris ramosa (Hope) C. Chr. and evaluation of cytotoxicity against liver and prostate cancer cell lines. Heliyon, 8, (11). doi:10.1016/j.heliyon.2022.e11286.
San, HT, Khine, HEE, Sritularak, B, Prompetchara, E, Chaotham, C, Che, CT, Likhitwitayawuid, K. (2022). Pinostrobin: An Adipogenic Suppressor from Fingerroot (Boesenbergia rotunda) and Its Possible Mechanisms. Foods, 11, (19). doi:10.3390/foods11193024.
Youn, I, Han, KY, Gurgul, A, Wu, Z, Lee, H, Che, CT. (2022). Chemical constituents of Entandrophragma angolense and their anti-inflammatory activity. Phytochemistry, 201. doi:10.1016/j.phytochem.2022.113276.
Elisabetsky, E, Che, CT. (2022). Editorial: Natural products as sources of innovative approaches in psychiatry. Frontiers in Psychiatry, 13. doi:10.3389/fpsyt.2022.929139.
Yang, CB, Lu, SN, Lu, C, Xu, MM, Duan, JA, Che, CT, Zhou, J, Zhao, M. (2022). A New C22-Quassinoid with Anti-Pancreatic Adenocarcinoma Activity from Seeds of Brucea javanica. Chemistry and Biodiversity, 19, (6). doi:10.1002/cbdv.202101004.
Zia-ur-Rehman, A, Gurgul, I, Youn, A, Maldonado, F, Wahid, CT, Che, T, Khan, . (2022). UHPLC-MS/MS-GNPS based phytochemical investigation of Equisetum arvense L. And evaluation of cytotoxicity against human melanoma and ovarian cancer cells. Saudi Journal of Biological Sciences, 29, (6). doi:10.1016/j.sjbs.2022.03.021.
Xu, M, Zhou, J, Heng, D, Su, X, Onakpa, MM, Bai, Y, Duan, JA, Che, CT, Bi, H, Zhao, M. (2022). Quinone Derivatives as Promising Anti-Helicobacter pylori Agents from Aerial Parts of Mitracarpus hirtus. Journal of Natural Products, 85, (4), 1029-1038. doi:10.1021/acs.jnatprod.1c01163.
Wu, ZL, Zhang, WY, Zhong, JC, Huang, XJ, Xu, W, Chen, MF, Weng, SQ, Zhang, DM, Che, CT, Ye, WC, Wang, Y. (2022). Angiogenesis-Inhibitory Piperidine Alkaloids from the Leaves of Microcos paniculata. Journal of Natural Products, 85, (2), 375-383. doi:10.1021/acs.jnatprod.1c00960.
Tao, W, Wang, N, Ruan, J, Cheng, X, Fan, L, Zhang, P, Lu, C, Hu, Y, Che, C, Sun, D, Duan, J, Zhao, M. (2022). Enhanced ROS-Boosted Phototherapy against Pancreatic Cancer via Nrf2-Mediated Stress-Defense Pathway Suppression and Ferroptosis Induction. ACS Applied Materials and Interfaces, 14, (5), 6404-6416. doi:10.1021/acsami.1c22861.
Professional Leadership
Hong Kong Poison Control Network, 2015 - 2024
Hong Kong Accreditation Service, 2014 - 2024
Education
Degrees:
B.S., The Chinese University of Hong Kong, Hong Kong, 1975
M.Phil., The Chinese University of Hong Kong, Hong Kong, 1977
Ph.D., University of Illinois at Chicago, United States, 1982
Postgraduate Training:
Postdoctoral Chemist, Ludwig Institute for Cancer Research, Canada, 1983
Selected Presentations
Warpeha, Katherine, Thnaibat, Nayfah, Che, Chun-Tao, Park, Thomas. (2018 January 01). Phenylalanine Boosts Brassica Production of Polyphenols for Medicinal Production.