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Photo of Chun-Tao Che

Chun-Tao Che


Harry H.S. Fong Professor of Pharmacognosy, College of Pharmacy
Director, WHO Collaborating Center for Traditional Medicine

Contact

Address:

833 South Wood St, Chicago, Illinois

Office Phone:

(312) 996-5234 (work)

Email:

chect@uic.edu

Related Sites:

About Heading link

Research Interests:
Drug lead discovery from medicinal plants; Traditional Chinese medicine; Quality and standardization of botanical supplements

Teaching and Supervision Heading link

PhLAMES 6 (PHAR 470), 1/10/2022 – 4/29/2022
Doctoral Research in Pharmacog (PMPG 599), 1/10/2022 – 4/29/2022
Doctoral Research in Pharmacog (PMPG 599), 8/23/2021 – 12/3/2021
PhLAMES 5 (PHAR 469), 8/23/2021 – 12/3/2021
Doctoral Research in Pharmacog (PMPG 599), 1/11/2021 – 4/30/2021
PDAT 2: GI/Endocrine (PHAR 502), 1/11/2021 – 4/30/2021
PDAT 2: GI/Endocrine (PHAR 502), 1/11/2021 – 4/30/2021
PhLAMES 6 (PHAR 470), 1/11/2021 – 4/30/2021

Selected Grants

Medicinal Plants of Laos: Discoveries, Conservation, and Community Engagement: Phase II, California Community Foundation., 7/1/2019 - 6/30/2023, Obligated Amount: $219090; Anticipated Amount: $219090

Medicinal Plants of Laos: Discoveries, Conservation, and Community Engagement: Phase II, California Community Foundation., 7/1/2019 - 6/30/2023, Obligated Amount: $219090; Anticipated Amount: $219090

Defining the role of isoprenylated xanthones from the mangosteen for enhancing degradation of full length and variant forms of androgen receptor in prostate cancer, National Institutes of Health (National Cancer Institute)., 1/1/2019 - 12/31/2023, Obligated Amount: $1411701; Anticipated Amount: $1765131

Rosemary as a Food Preservative: Implications for Gastrointestinal Health, US Department of Agriculture (National Institute of Food and Agriculture)., 1/1/2017 - 4/14/2022, Obligated Amount: $470000; Anticipated Amount: $470000

California Community Foundation (CCF) Elina Vesara Ostern Fund, California Community Foundation., 7/1/2013 - 12/31/2014, Obligated Amount: $53804; Anticipated Amount: $53804

Technical Development of a Herb-based Topical Application for Psoriasis Treatment, Innovation and Technology Commission., 4/1/2007 - 9/30/2008, No Obligated Amount Set; No Anticipated Amount Set

Selected Publications

Gurgul, Aleksandra, Nauman, Mirielle C, Wu, Zhenlong, Shetye, Gauri, Ma, Rui, Youn, Isoo, Souliya, Onevilay, Bisson, Jonathan, Johnson, Jeremy J, Che, Chun-Tao. (2022). Chemical constituents of the stem of Marsypopetalum modestum and their bioactivities.. Natural Product Research, 1-8. doi:10.1080/14786419.2022.2097229.

Youn, Isoo, Han, Kyu-Yeon, Gurgul, Aleksandra, Wu, Zhenlong, Lee, Hyun, Che, Chun-Tao. (2022). Chemical constituents of Entandrophragma angolense and their anti-inflammatory activity. Phytochemistry, 201, 113276. doi:10.1016/j.phytochem.2022.113276.

Yang, Cheng‐Bin, Lu, Si‐Nan, Lu, Cai, Xu, Ming‐Ming, Duan, Jin‐Ao, Che, Chun‐Tao, Zhou, Junfei, Zhao, Ming. (2022). A New C22‐Quassinoid with Anti‐Pancreatic Adenocarcinoma Activity from Seeds of Brucea javanica. Chemistry & Biodiversity, 19, (6), e202101004. doi:10.1002/cbdv.202101004.

Xu, Mingming, Zhou, Junfei, Heng, Ding, Su, Xiaorong, Onakpa, Monday M, Bai, Yuefan, Duan, Jin-Ao, Che, Chun-Tao, Bi, Hongkai, Zhao, Ming. (2022). Quinone Derivatives as Promising Anti-Helicobacter pylori Agents from Aerial Parts of Mitracarpus hirtus. Journal of Natural Products, 85, (4), 1029-1038. doi:10.1021/acs.jnatprod.1c01163.

Zia-ur-Rehman, Aleksandra, Gurgul, Isoo, Youn, Amanda, Maldonado, Fazli, Wahid, Chun-Tao, Che, Taous, Khan, . (2022). UHPLC-MS/MS-GNPS based phytochemical investigation of Equisetum arvense L. And evaluation of cytotoxicity against human melanoma and ovarian cancer cells. Saudi Journal of Biological Sciences, 29, (6), 103271. doi:10.1016/j.sjbs.2022.03.021.

Wu, Zhen-Long, Zhang, Wei-Yan, Zhong, Jin-Cheng, Huang, Xiao-Jun, Xu, Wei, Chen, Min-Feng, Weng, Shao-Quan, Zhang, Dong-Mei, Che, Chun-Tao, Ye, Wen-Cai, Wang, Ying. (2022). Angiogenesis-Inhibitory Piperidine Alkaloids from the Leaves of Microcos paniculata. Journal of Natural Products, 85, (2), 375-383. doi:10.1021/acs.jnatprod.1c00960.

Tao, Weiwei, Wang, Neng, Ruan, Jie, Cheng, Xiaolan, Fan, Lu, Zhang, Pengfei, Lu, Cai, Hu, Yue, Che, Chuntao, Sun, Dongdong, Duan, Jinao, Zhao, Ming. (2022). Enhanced ROS-Boosted Phototherapy against Pancreatic Cancer via Nrf2-Mediated Stress-Defense Pathway Suppression and Ferroptosis Induction. ACS Applied Materials & Interfaces, 14, (5), 6404-6416. doi:10.1021/acsami.1c22861.

Dutta, Naibedya, Pemmaraju, Deepak Bharadwaj, Ghosh, Suvranil, Ali, Asif, Mondal, Ayan, Majumder, Chirantan, Nelson, Vinod K, Mandal, Subhash C, Misra, Anup K, Rengan, Aravind K, Ravichandiran, Velyutham, Che, Chun-Tao, Gurova, Katerina V, Gudkov, Andrei V, Pal, Mahadeb. (2021). Alkaloid-rich fraction of Ervatamia coronaria sensitizes colorectal cancer through modulating AMPK and mTOR signalling pathways. Journal of Ethnopharmacology, 283, 114666. doi:10.1016/j.jep.2021.114666.

Rice, Amy J, Pesavento, Russell P, Ren, Jinhong, Youn, Isoo, Kwon, Youngjin, Ellepola, Kassapa, Che, Chun-Tao, Johnson, Michael E, Lee, Hyun. (2021). Identification of Small Molecule Inhibitors against Staphylococcus aureus Dihydroorotase via HTS. International Journal of Molecular Sciences, 22, (18), 9984. doi:10.3390/ijms22189984.

Professional Leadership

Hong Kong Poison Control Network, 2015 - 2024

Hong Kong Accreditation Service, 2014 - 2024

Education

Degrees:
B.S., The Chinese University of Hong Kong, Hong Kong, 1975
M.Phil., The Chinese University of Hong Kong, Hong Kong, 1977
Ph.D., University of Illinois at Chicago, United States, 1982

Postgraduate Training:
Postdoctoral Chemist, Ludwig Institute for Cancer Research, Canada, 1983

Selected Presentations

Warpeha, Katherine, Thnaibat, Nayfah, Che, Chun-Tao, Park, Thomas. (2018 September 01). Phenylalanine Boosts Brassica Production of Polyphenols for Medicinal Production.