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Photo of Chun-Tao Che

Chun-Tao Che


Harry H.S. Fong Professor of Pharmacognosy, College of Pharmacy
Director, WHO Collaborating Center for Traditional Medicine

Contact

Address:

833 South Wood St, Chicago, Illinois

Office Phone:

(312) 996-5234 (work)

Email:

chect@uic.edu

Related Sites:

About Heading link

Research Interests:
Drug lead discovery from medicinal plants; Traditional Chinese medicine; Quality and standardization of botanical supplements

Teaching and Supervision Heading link

PSCI Ph.D. Thesis Research (PSCI 599), 8/21/2023 – 12/1/2023
PhLAMES 7 (PHAR 471), 8/21/2023 – 12/1/2023
Doctoral Research in Pharmacog (PMPG 599), 6/12/2023 – 8/4/2023
Doctoral Research in Pharmacog (PMPG 599), 1/9/2023 – 4/28/2023
PhLAMES 6 (PHAR 470), 1/9/2023 – 4/28/2023
Undergrad Res Pharm Sci (PSCI 380), 1/9/2023 – 4/28/2023
Undergrad Res Exp Pharm Sci (PSCI 300), 1/9/2023 – 4/28/2023
PhLAMES 5 (PHAR 469), 8/22/2022 – 12/2/2022
Undergrad Res Pharm Sci (PSCI 380), 8/22/2022 – 12/2/2022

Selected Grants

Medicinal Plants of Laos: Discoveries, Conservation, and Community Engagement: Phase II, California Community Foundation., 7/1/2019 - 6/30/2023, Obligated Amount: $219090; Anticipated Amount: $219090

Medicinal Plants of Laos: Discoveries, Conservation, and Community Engagement: Phase II, California Community Foundation., 7/1/2019 - 6/30/2023, Obligated Amount: $219090; Anticipated Amount: $219090

Defining the role of isoprenylated xanthones from the mangosteen for enhancing degradation of full length and variant forms of androgen receptor in prostate cancer, National Institutes of Health (National Cancer Institute)., 1/1/2019 - 12/31/2023, Obligated Amount: $1758062; Anticipated Amount: $1765131

Rosemary as a Food Preservative: Implications for Gastrointestinal Health, US Department of Agriculture (National Institute of Food and Agriculture)., 1/1/2017 - 4/14/2022, Obligated Amount: $470000; Anticipated Amount: $470000

California Community Foundation (CCF) Elina Vesara Ostern Fund, California Community Foundation., 7/1/2013 - 12/31/2014, Obligated Amount: $53804; Anticipated Amount: $53804

Technical Development of a Herb-based Topical Application for Psoriasis Treatment, Innovation and Technology Commission., 4/1/2007 - 9/30/2008, Obligated Amount: $140341; No Anticipated Amount Set

Selected Publications

Gurgul, Aleksandra, Khin, Manead, Souliya, Onevilay, Sydara, Kongmany, Burdette, Joanna E, Johnson, Jeremy J, Che, Chun-Tao. (2024). Acetogenins from the Stem of Uvaria rufa and Their Cytotoxic Activity. Journal of Natural Products. doi:10.1021/acs.jnatprod.3c00838.

Gurgul, Aleksandra, Wu, Zhenlong, Han, Kyu-Yeon, Shetye, Gauri, Sydara, Kongmany, Souliya, Onevilay, Johnson, Jeremy J, Che, Chun-Tao. (2023). Polyoxygenated cyclohexene derivatives and other constituents of Uvaria rufa stem. Phytochemistry, 216, 113884. doi:10.1016/j.phytochem.2023.113884.

Gurgul, Aleksandra, Nauman, Mirielle C, Wu, Zhenlong, Shetye, Gauri, Ma, Rui, Youn, Isoo, Souliya, Onevilay, Bisson, Jonathan, Johnson, Jeremy J, Che, Chun-Tao. (2023). Chemical constituents of the stem of Marsypopetalum modestum and their bioactivities. Natural Product Research, 37, (21), 3623-3630. doi:10.1080/14786419.2022.2097229.

Xu, Mingming, Di, Di, Fan, Lu, Ma, Yingrun, Wei, Xinyi, Shang, Er-Xin, Onakpa, Monday M, Johnson, Oluwatosin O, Duan, Jin-Ao, Che, Chun-Tao, Zhou, Junfei, Zhao, Ming. (2023). Structurally diverse (9β-H)-pimarane derivatives with six frameworks from the leaves of Icacina oliviformis and their cytotoxic activities. Phytochemistry, 214, 113804. doi:10.1016/j.phytochem.2023.113804.

Lee, Hyun, Youn, Isoo, Demissie, Robel, Vaid, Tasneem M, Che, Chun-Tao, Azar, Dimitri T, Han, Kyu-Yeon. (2023). Identification of small molecule inhibitors against MMP-14 via High-Throughput screening. Bioorganic & Medicinal Chemistry, 85, 117289. doi:10.1016/j.bmc.2023.117289.

Zia-ur-Rehman, Hafiz Majid, Rasheed, Kashif, Bashir, Aleksandra, Gurgul, Fazli, Wahid, Chun-Tao, Che, Irum, Shahzadi, Taous, Khan, . (2022). UHPLC-MS/MS-GNPS based phytochemical investigation of Dryopteris ramosa (Hope) C. Chr. and evaluation of cytotoxicity against liver and prostate cancer cell lines. Heliyon, 8, (11), e11286. doi:10.1016/j.heliyon.2022.e11286.

Youn, Isoo, Han, Kyu-Yeon, Gurgul, Aleksandra, Wu, Zhenlong, Lee, Hyun, Che, Chun-Tao. (2022). Chemical constituents of Entandrophragma angolense and their anti-inflammatory activity. Phytochemistry, 201, 113276. doi:10.1016/j.phytochem.2022.113276.

Zia-ur-Rehman, Aleksandra, Gurgul, Isoo, Youn, Amanda, Maldonado, Fazli, Wahid, Chun-Tao, Che, Taous, Khan, . (2022). UHPLC-MS/MS-GNPS based phytochemical investigation of Equisetum arvense L. And evaluation of cytotoxicity against human melanoma and ovarian cancer cells. Saudi Journal of Biological Sciences, 29, (6), 103271. doi:10.1016/j.sjbs.2022.03.021.

Yang, Cheng‐Bin, Lu, Si‐Nan, Lu, Cai, Xu, Ming‐Ming, Duan, Jin‐Ao, Che, Chun‐Tao, Zhou, Junfei, Zhao, Ming. (2022). A New C22‐Quassinoid with Anti‐Pancreatic Adenocarcinoma Activity from Seeds of Brucea javanica. Chemistry & Biodiversity, 19, (6), e202101004. doi:10.1002/cbdv.202101004.

Professional Leadership

Hong Kong Poison Control Network, 2015 - 2024

Hong Kong Accreditation Service, 2014 - 2024

Education

Degrees:
B.S., The Chinese University of Hong Kong, Hong Kong, 1975
M.Phil., The Chinese University of Hong Kong, Hong Kong, 1977
Ph.D., University of Illinois at Chicago, United States, 1982

Postgraduate Training:
Postdoctoral Chemist, Ludwig Institute for Cancer Research, Canada, 1983