Photo of Chun-Tao Che

Chun-Tao Che


Harry H.S. Fong Professor of Pharmacognosy, College of Pharmacy
Director, WHO Collaborating Center for Traditional Medicine

Contact

Address:

833 South Wood St, Chicago, Illinois

Office Phone:

(312) 996-5234 (work)

Email:

chect@uic.edu

Related Sites:

About

Research Interests:
Drug lead discovery from medicinal plants; Traditional Chinese medicine; Quality and standardization of botanical supplements

Teaching and Supervision

Doctoral Research in Pharmacog (PMPG 599), 8/23/2021 – 12/3/2021
PhLAMES 5 (PHAR 469), 8/23/2021 – 12/3/2021
Doctoral Research in Pharmacog (PMPG 599), 1/11/2021 – 4/30/2021
PDAT 2: GI/Endocrine (PHAR 502), 1/11/2021 – 4/30/2021
PDAT 2: GI/Endocrine (PHAR 502), 1/11/2021 – 4/30/2021
PhLAMES 6 (PHAR 470), 1/11/2021 – 4/30/2021

Selected Grants

Medicinal Plants of Laos: Discoveries, Conservation, amd Community Engagement: Phase II, California Community Foundation., 7/1/2019 - 6/30/2022, Obligated Amount: $219090; Anticipated Amount: $219090

Medicinal Plants of Laos: Discoveries, Conservation, amd Community Engagement: Phase II, California Community Foundation., 7/1/2019 - 6/30/2022, Obligated Amount: $219090; Anticipated Amount: $219090

Defining the role of isoprenylated xanthones from the mangosteen for enhancing degradation of full length and variant forms of androgen receptor in prostate cancer, National Institutes of Health (National Cancer Institute)., 1/1/2019 - 12/31/2023, Obligated Amount: $1058271; Anticipated Amount: $1765131

Rosemary as a Food Preservative: Implications for Gastrointestinal Health, US Department of Agriculture (National Institute of Food and Agriculture)., 1/1/2017 - 4/14/2022, Obligated Amount: $470000; Anticipated Amount: $470000

California Community Foundation (CCF) Elina Vesara Ostern Fund, California Community Foundation., 7/1/2013 - 12/31/2014, Obligated Amount: $53804; Anticipated Amount: $53804

Technical Development of a Herb-based Topical Application for Psoriasis Treatment, Innovation and Technology Commission., 4/1/2007 - 9/30/2008, No Obligated Amount Set; No Anticipated Amount Set

Selected Publications

Burton, TCJ, Lankin, DC, Nikolic, D, Guo, B, Ju, J, Dietz, BM, Che, CT, Soejarto, DD, van Breemen, RB. (2021). Isolation and elucidation of two isoflavonoids from an American Indian plant, Amorpha canescens Pursh, using Magnetic Microbead Affinity Selection Screening (MagMASS) for estrogen receptor alpha ligands. Phytochemistry Letters, 45, 110-116. doi:10.1016/j.phytol.2021.07.018.

Rice, AJ, Pesavento, RP, Ren, J, Youn, I, Kwon, Y, Ellepola, K, Che, CT, Johnson, ME, Lee, H. (2021). Identification of small molecule inhibitors against staphylococcus aureus dihydroorotase via hts. International Journal of Molecular Sciences, 22, (18). doi:10.3390/ijms22189984.

Zhang, Pengfei, Tao, Weiwei, Lu, Cai, Fan, Lu, Jiang, Qihang, Yang, Chengbin, Shang, Erxin, Cheng, Haibo, Che, Chuntao, Duan, Jinao, Zhao, Ming. (2021). Bruceine A induces cell growth inhibition and apoptosis through PFKFB4/GSK3β signaling in pancreatic cancer.. Pharmacol Res, 169, 105658. doi:10.1016/j.phrs.2021.105658.

Xu, MM, Zhou, J, Zeng, L, Xu, J, Onakpa, MM, Duan, JA, Che, CT, Bi, H, Zhao, M. (2021). Pimarane-derived diterpenoids with anti-: Helicobacter pylori activity from the tuber of Icacina trichantha. Organic Chemistry Frontiers, 8, (12), 3014-3022. doi:10.1039/d1qo00374g.

Huang, Ya-Ping, Zhao, Yuan-Yu, Johnson, Oluwatosin O, Zhang, Jian, Zhao, Ming, Che, Chun-Tao, Yin, Zhi-Qi. (2021). Further prenylated anthranoids from Harungana madagascariensis.. Phytochemistry, 186, 112711. doi:10.1016/j.phytochem.2021.112711.

Sun, Meng, Guo, Brian, Xu, Mingming, Zhao, Ming, Onakpa, Monday M, Wu, Zhenlong, Burdette, Joanna E, Che, Chun-Tao. (2021). (9βH)- and 17-Nor-Pimaranes from Icacina oliviformis.. J Nat Prod, 84, (4), 949-955. doi:10.1021/acs.jnatprod.9b01131.

Youn, Isoo, Wu, Zhenlong, Papa, Samiya, Burdette, Joanna E, Oyawaluja, Bamisaye O, Lee, Hyun, Che, Chun-Tao. (2021). Limonoids and other triterpenoids from Entandrophragma angolense.. Fitoterapia, 150, 104846. doi:10.1016/j.fitote.2021.104846.

Lu, C, Fan, L, Zhang, PF, Tao, WW, Yang, CB, Shang, EX, Chen, FY, Che, CT, Cheng, HB, Duan, JA, Zhao, M. (2021). A novel P38α MAPK activator Bruceine A exhibits potent anti-pancreatic cancer activity. Computational and Structural Biotechnology Journal, 19, 3437-3450. doi:10.1016/j.csbj.2021.06.011.

Guo, B, Zhao, M, Wu, Z, Onakpa, MM, Burdette, JE, Che, CT. (2020). Corrigendum to ‘19-nor-pimaranes from Icacina trichantha’ [Fitoterapia. 144 (2020) 104612] (Fitoterapia (2020) 144, (S0367326X20301945), (10.1016/j.fitote.2020.104612)). Fitoterapia, 146. doi:10.1016/j.fitote.2020.104656.

Education

Degrees:
B.S., The Chinese University of Hong Kong, Hong Kong, 1975
M.Phil., The Chinese University of Hong Kong, Hong Kong, 1977
Ph.D., University of Illinois at Chicago, United States, 1982

Postgraduate Training:
Postdoctoral Chemist, Ludwig Institute for Cancer Research, Canada, 1983

Selected Presentations

Warpeha, Katherine, Thnaibat, Nayfah, Che, Chun-Tao, Park, Thomas. (2018 September 01). Phenylalanine Boosts Brassica Production of Polyphenols for Medicinal Production.