Photo of Douglas D. Thomas

Douglas D. Thomas


Associate Professor, College of Pharmacy - Medicinal Chemistry and Pharmacognosy
Director of Graduate Studies, College of Pharmacy - Medicinal Chemistry and Pharmacognosy

Teaching and Supervision

Doctoral Restch in Med Chem (MDCH 599), 8/23/2021 – 12/3/2021
Research Presentation (PSCI 502), 8/23/2021 – 12/3/2021
Doctoral Restch in Med Chem (MDCH 599), 1/11/2021 – 4/30/2021
Biomedicinal Chemistry (PHAR 423), 1/11/2021 – 4/30/2021
Biomedicinal Chemistry (PHAR 423), 1/11/2021 – 4/30/2021

Selected Publications

McGinity, CL, Palmieri, EM, Somasundaram, V, Bhattacharyya, DD, Ridnour, LA, Cheng, RYS, Ryan, AE, Glynn, SA, Thomas, DD, Miranda, KM, Anderson, SK, Lockett, SJ, McVicar, DW, Wink, DA. (2021). Nitric oxide modulates metabolic processes in the tumor immune microenvironment. International Journal of Molecular Sciences, 22, (13). doi:10.3390/ijms22137068.

Kuschman, HP, Palczewski, MB, Thomas, DD. (2021). Nitric oxide and hydrogen sulfide: Sibling rivalry in the family of epigenetic regulators. Free Radical Biology and Medicine, 170, 34-43. doi:10.1016/j.freeradbiomed.2021.01.010.

Palczewski, MB, Kuschman, HP, Bovee, R, Hickok, JR, Thomas, DD. (2021). Vorinostat exhibits anticancer effects in triple-negative breast cancer cells by preventing nitric oxide-driven histone deacetylation. Biological Chemistry, 402, (4), 501-512. doi:10.1515/hsz-2020-0323.

Palczewski, MB, Petraitis, H, Thomas, DD. (2019). Nitric oxide is an epigenetic regulator of histone post-translational modifications in cancer. Current Opinion in Physiology, 9, 94-99. doi:10.1016/j.cophys.2019.05.006.

Somasundaram, V, Basudhar, D, Bharadwaj, G, No, JH, Ridnour, LA, Cheng, RYS, Fujita, M, Thomas, DD, Anderson, SK, McVicar, DW, Wink, DA. (2019). Molecular mechanisms of nitric oxide in cancer progression, signal transduction, and metabolism. Antioxidants and Redox Signaling, 30, (8), 1124-1143. doi:10.1089/ars.2018.7527.

Thomas, Douglas D. (2018). Oxidative Stress. Encyclopedia of Biophysics. (pp. 1-7). doi:10.1007/978-3-642-35943-9_48-1.

Sahni, S, Hickok, JR, Thomas, DD. (2018). Nitric oxide reduces oxidative stress in cancer cells by forming dinitrosyliron complexes. Nitric Oxide – Biology and Chemistry, 76, 37-44. doi:10.1016/j.niox.2018.03.003.

Thomas, DD, Corey, C, Hickok, J, Wang, Y, Shiva, S. (2018). Differential mitochondrial dinitrosyliron complex formation by nitrite and nitric oxide. Redox Biology, 15, 277-283. doi:10.1016/j.redox.2017.12.007.

Bovee, Rhea, Pham, Vy, Fernandez, Jenna, Tretyakova, Natalia, Thomas, Douglas D. (2018). P-228 Nitric oxide is an epigenetic regulator of gene expression by directly controlling DNA methylation patterns. Free Radical Biology and Medicine, 120, s114. doi:10.1016/j.freeradbiomed.2018.04.375.

Professional Leadership

President, Nitric Oxide Society, 1/1/2018 - Present

Education

Degrees:
BS, Washington State University, United States, 1992
PhD, Louisiana State University, United States, 2000

Selected Presentations

Thomas, Douglas. (2021 November 16). Epigenetic regulation by Nitric oxide. 27th Annual Conference of the Society for Redox Biology & Medicine. Virtual.
Thomas, Douglas, Thomas, Douglas. (2021 March 16). Epigenetic regulation: the third pillar of nitric oxide signaling. 20th Biennial Meeting of Society for Free Radical Research International. Virtual.
Thomas, Douglas, Thomas, Douglas. (2020 November 18). Epigenetic regulation by Nitric oxide. Nitric Oxide: Physiology, Pharmacology, and Therapeutic Applications. Virtual.
Thomas, Douglas. (2020 January 16). Epigenetic regulation: the third pillar of nitric oxide signaling. Douglas D Thomas. Minneapolis.