Douglas D. Thomas
Associate Professor, College of Pharmacy - Medicinal Chemistry and Pharmacognosy
Director of Graduate Studies, College of Pharmacy - Medicinal Chemistry and Pharmacognosy
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Biomedicinal Chemistry (PHAR 423), 4/22/2022 – 4/28/2021
Biomedicinal Chemistry (PHAR 423), 1/10/2022 – 4/29/2022
Biomedicinal Chemistry (PHAR 423), 1/10/2022 – 4/29/2022
Doctoral Restch in Med Chem (MDCH 599), 1/10/2022 – 4/29/2022
Research Techniques in Pharmacognosy (PSCI 520), 11/29/2021 – 12/1/2021
Pharm 410 (Phar 410), 11/8/2021 – 11/18/2021
Pharmaceutical Applications of Genomics and Bioinformatics (PMMP 412/MDCH 412), 9/14/2021 – 9/21/2021
Doctoral Restch in Med Chem (MDCH 599), 8/23/2021 – 12/3/2021
Research Presentation (PSCI 502), 8/23/2021 – 12/3/2021
Selected Grants
2021 Vahlteich Bridge funding, Vahlteich., 11/1/2022 - 10/31/2022, Obligated Amount: $25000; Anticipated Amount: $25000
Selected Publications
Thomas, Douglas D, Shiva, Sruti. (2022). Methods to the Madness – Fundamental Techniques in NO Research. Nitric Oxide, 122-123, 45-46. doi:10.1016/j.niox.2022.03.003.
McGinity, Christopher L, Palmieri, Erika M, Somasundaram, Veena, Bhattacharyya, Dibyangana D, Ridnour, Lisa A, Cheng, Robert YS, Ryan, Aideen E, Glynn, Sharon A, Thomas, Douglas D, Miranda, Katrina M, Anderson, Stephen K, Lockett, Stephen J, McVicar, Daniel W, Wink, David A. (2021). Nitric Oxide Modulates Metabolic Processes in the Tumor Immune Microenvironment. International Journal of Molecular Sciences, 22, (13), 7068. doi:10.3390/ijms22137068.
Kuschman, Hannah Petraitis, Palczewski, Marianne B, Thomas, Douglas D. (2021). Nitric oxide and hydrogen sulfide: Sibling rivalry in the family of epigenetic regulators. Free Radical Biology and Medicine, 170, 34-43. doi:10.1016/j.freeradbiomed.2021.01.010.
Palczewski, Marianne B, Kuschman, Hannah Petraitis, Bovee, Rhea, Hickok, Jason R, Thomas, Douglas D. (2021). Vorinostat exhibits anticancer effects in triple-negative breast cancer cells by preventing nitric oxide-driven histone deacetylation. Biological Chemistry, 402, (4), 501-512. doi:10.1515/hsz-2020-0323.
Palczewski, Marianne B, Petraitis, Hannah, Thomas, Douglas D. (2019). Nitric oxide as an epigenetic regulator of histone posttranslational modifications in cancer. Current Opinion in Physiology, 9, 94-99. doi:10.1016/j.cophys.2019.05.006.
Thomas, Douglas D. (2018). Oxidative Stress. Encyclopedia of Biophysics. (pp. 1-7). doi:10.1007/978-3-642-35943-9_48-1.
Somasundaram, Veena, Basudhar, Debashree, Bharadwaj, Gaurav, No, Jae Hong, Ridnour, Lisa A, Cheng, Robert YS, Fujita, Mayumi, Thomas, Douglas D, Anderson, Stephen K, McVicar, Daniel W, Wink, David A. (2018). Molecular Mechanisms of Nitric Oxide in Cancer Progression, Signal Transduction, and Metabolism. Antioxidants & Redox Signaling, 30, (8), 1124-1143. doi:10.1089/ars.2018.7527.
Bovee, Rhea, Pham, Vy, Fernandez, Jenna, Tretyakova, Natalia, Thomas, Douglas D. (2018). P-228 Nitric oxide is an epigenetic regulator of gene expression by directly controlling DNA methylation patterns. Free Radical Biology and Medicine, 120, s114. doi:10.1016/j.freeradbiomed.2018.04.375.
Sahni, Sumit, Hickok, Jason R, Thomas, Douglas D. (2018). Nitric oxide reduces oxidative stress in cancer cells by forming dinitrosyliron complexes. Nitric Oxide, 76, 37-44. doi:10.1016/j.niox.2018.03.003.
Professional Leadership
President, Nitric Oxide Society, 1/1/2018 - Present
Education
Degrees:
BS, Washington State University, United States, 1992
PhD, Louisiana State University, United States, 2000
Selected Presentations
Douglas, Thomas. (2022 June 09). Epigenetic regulation: the third pillar of nitric oxide signaling. 2021 Great Lakes Regional Meeting. Virtual.
Thomas, Douglas. (2021 November 16). Epigenetic regulation by Nitric oxide. 27th Annual Conference of the Society for Redox Biology & Medicine. Virtual.
Douglas, Thomas. (2021 June 01). nitric oxide as epigenetic regulator. Progress in Plant Biology. Virtual.
Thomas, Douglas, Thomas, Douglas. (2021 March 16). Epigenetic regulation: the third pillar of nitric oxide signaling. 20th Biennial Meeting of Society for Free Radical Research International. Virtual.
Thomas, Douglas, Thomas, Douglas. (2020 November 18). Epigenetic regulation by Nitric oxide. Nitric Oxide: Physiology, Pharmacology, and Therapeutic Applications. Virtual.
Douglas, Thomas. (2022 November 15). Nitric oxide is an epigenetic regulator. Gasotransmitter symposium honoring Marilyn Jorns. Virtual.