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Photo of Gauri S. Shetye

Gauri S. Shetye

Research Assistant Professor, Pharmaceutical Sciences

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Selected Grants

Identification of antimicrobial reagents against TB and ESKAPE pathogens from bacteria collected in Vietnam�., Vietnam Academy of Science & Technology (Inst of Marine Biochemistry)., 5/5/2021 - 4/30/2023, Obligated Amount: $39975; Anticipated Amount: $39975

Enhancing basic and translational TB research in northern Vietnam, National Institutes of Health., 7/1/2017 - 6/30/2022, Obligated Amount: $52396; No Anticipated Amount Set

Selected Publications

Kamat, V, Poojary, B, Puthran, D, Das, VB, Kumar, BK, Sankaranarayan, M, Shetye, G, Ma, R, Franzblau, SG, Nayak, SP. (2023). Synthesis, antimycobacterial, cytotoxicity, anti-inflammatory, in silico studies and molecular dynamics of pyrazole-embedded thiazolidin-4-one hybrids. Archiv der Pharmazie, 356, (3). doi:10.1002/ardp.202200444.

Lee, SY, Shetye, GS, Son, SR, Lee, H, Klein, LL, Yoshihara, JK, Ma, R, Franzblau, SG, Cho, S, Jang, DS. (2023). Anti-Microbial Activity of Aliphatic Alcohols from Chinese Black Cardamom (Amomum tsao-ko) against Mycobacterium tuberculosis H37Rv. Plants, 12, (1). doi:10.3390/plants12010034.

Hong, J, Duc, NM, Jeong, BC, Cho, S, Shetye, G, Cao, J, Lee, H, Jeong, C, Lee, H, Suh, JW. (2023). Identification of the inhibitory mechanism of ecumicin and rufomycin 4-7 on the proteolytic activity of Mycobacterium tuberculosis ClpC1/ClpP1/ClpP2 complex. Tuberculosis, 138. doi:10.1016/

Kim, HB, Bacik, JP, Wu, R, Jha, RK, Hebron, M, Triandafillou, C, McCown, JE, Baek, NI, Kim, JH, Kim, YJ, Goulding, CW, Strauss, CEM, Schmidt, JG, Shetye, GS, Ryoo, S, Jo, EK, Jeon, YH, Hung, LW, Terwilliger, TC, Kim, CY. (2022). Label-free affinity screening, design and synthesis of inhibitors targeting the Mycobacterium tuberculosis L-alanine dehydrogenase. PLoS ONE, 17, (11 November). doi:10.1371/journal.pone.0277670.

Liu, R, Marshall, K, Ma, R, Lien Thi Pham, K, Shetye, G, Liu, Z, Cho, S, Jeong, H, Franzblau, SG, Moraski, GC, Miller, MJ. (2022). Syntheses and studies of deuterated Imdiazo[1,2-a]pyridine-3-carboxamides with potent anti-tuberculosis activity and improved metabolic properties. Bioorganic Chemistry, 128. doi:10.1016/j.bioorg.2022.106074.

Ristroph, KD, McManus, SA, Shetye, G, Cho, SH, Lee, D, Szekely, Z, Sinko, PJ, Franzblau, SG, Prud’homme, RK. (2022). Targeted Antitubercular Peptide Nanocarriers Prepared by Flash NanoPrecipitation with Hydrophobic Ion Pairing. Advanced Materials Technologies, 7, (11). doi:10.1002/admt.202101748.

Zhou, B, Shetye, G, Wolf, NM, Chen, SN, Qader, M, Ray, GJ, Lankin, DC, Cho, S, Cheng, J, Suh, JW, Franzblau, SG, McAlpine, JB, Pauli, GF. (2022). New Rufomycins from Streptomyces atratus MJM3502 Expand Anti- Mycobacterium tuberculosis Structure-Activity Relationships. Organic Letters, 24, (40), 7265-7270. doi:10.1021/acs.orglett.2c02493.

Pasha, MA, Mondal, S, Panigrahi, N, Shetye, G, Ma, R, Franzblau, SG, Zheng, YT, Murugesan, S. (2022). One-Pot Synthesis of Novel Hydrazono-1,3-Thıazolıdın-4-One Derivatives as Anti-HIV and Anti-Tubercular Agents: Synthesıs, Bıologıcal Evalu-atıon, Molecular Modelling and Admet Studıes. Current HIV Research, 20, (3), 255-271. doi:10.2174/1570162X20666220512163049.

Gurgul, A, Nauman, MC, Wu, Z, Shetye, G, Ma, R, Youn, I, Souliya, O, Bisson, J, Johnson, JJ, Che, CT. (2022). Chemical constituents of the stem of Marsypopetalum modestum and their bioactivities. Natural Product Research. doi:10.1080/14786419.2022.2097229.