Gauri S. Shetye
Research Assistant Professor, Pharmaceutical Sciences
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Selected Grants
Marine sponge depsipeptides to minimize antibiotic collateral damage, National Institutes of Health (National Institute of Allergy and Infectious Diseases)., 5/19/2023 - 4/30/2025, Obligated Amount: $199875; Anticipated Amount: $439725
Identification of antimicrobial reagents against TB and ESKAPE pathogens from bacteria collected in Vietnam�., Vietnam Academy of Science & Technology (Inst of Marine Biochemistry)., 5/5/2021 - 4/30/2023, Obligated Amount: $39975; Anticipated Amount: $39975
Enhancing basic and translational TB research in northern Vietnam, National Institutes of Health., 7/1/2017 - 6/30/2022, Obligated Amount: $52396; No Anticipated Amount Set
Selected Publications
Kumar, Boddupalli Venkata Siva, Khetmalis, Yogesh Mahadu, Chaitanya, Kosana Sai, Chandu, Ala, Shetye, Gauri, Ma, Rui, Murugesan, Sankaranarayanan, Franzblau, Scott G, Sekhar, Kondapalli Venkata Gowri Chandra. (2024). Design, synthesis and biological evaluation of novel pyrido-[2,3-d]-pyrimidin-2-amine analogues as antimycobacterial agents. Journal of Molecular Structure, 1303, 137600. doi:10.1016/j.molstruc.2024.137600.
Wang, Weihong, Lee, JunI, Roh, Eun, Shetye, Gauri, Cao, Jin, McAlpine, James, Pauli, Guido, Franzblau, Scott, Vu, Thi Hanh Nguyen, Quach, Ngoc Tung, Oh, Eunseok, Park, Kyu-Hyung, Park, Chanyoon, Cho, Youbin, Jang, Hyeseon, Han, SongJoo, Kim, Hiyoung, Cho, Sanghyun, Phi, Quyet-Tien, Kang, Heonjoong. (2024). Cavomycins A–C, Linear Oligomer Depsipeptides from an Annelid-Associated Streptomyces cavourensis. Journal of Natural Products. doi:10.1021/acs.jnatprod.3c01275.
Gurgul, Aleksandra, Wu, Zhenlong, Han, Kyu-Yeon, Shetye, Gauri, Sydara, Kongmany, Souliya, Onevilay, Johnson, Jeremy J, Che, Chun-Tao. (2023). Polyoxygenated cyclohexene derivatives and other constituents of Uvaria rufa stem. Phytochemistry, 216, 113884. doi:10.1016/j.phytochem.2023.113884.
Gurgul, Aleksandra, Nauman, Mirielle C, Wu, Zhenlong, Shetye, Gauri, Ma, Rui, Youn, Isoo, Souliya, Onevilay, Bisson, Jonathan, Johnson, Jeremy J, Che, Chun-Tao. (2023). Chemical constituents of the stem of Marsypopetalum modestum and their bioactivities. Natural Product Research, 37, (21), 3623-3630. doi:10.1080/14786419.2022.2097229.
Nandikolla, Adinarayana, Khetmalis, Yogesh Mahadu, Venkata Siva Kumar, Boddupalli, Chandu, Ala, Karan Kumar, Banoth, Shetye, Gauri, Ma, Rui, Murugesan, Sankaranarayanan, Franzblau, Scott G, Chandra Sekhar, Kondapalli Venkata Gowri. (2023). Design, synthesis and biological evaluation of phenanthridine amide and 1,2,3-triazole analogues against Mycobacterium tuberculosis. RSC Medicinal Chemistry, 14, (8), 1549-1561. doi:10.1039/d3md00115f.
Lee, Jung-Ho, Ma, Rui, Nguyen, Linh, Khan, Shahebraj, Qader, Mallique, Mpofu, Enock, Shetye, Gauri, Krull, Nyssa K, Augustinović, Mario, Omarsdottir, Sesselja, Cho, Sanghyun, Franzblau, Scott G, Murphy, Brian T. (2023). Discovery of a New Antibiotic Demethoxytetronasin Using a Dual-Sided Agar Plate Assay (DAPA). ACS Infectious Diseases, 9, (8), 1593-1601. doi:10.1021/acsinfecdis.3c00171.
Kamat, Vinuta, Poojary, Boja, Puthran, Divyaraj, Das, Vishwa B, Kumar, Banoth K, Sankaranarayan, Murugesan, Shetye, Gauri, Ma, Rui, Franzblau, Scott G, Nayak, Suresh P. (2023). Synthesis, antimycobacterial, cytotoxicity, anti‐inflammatory, in silico studies and molecular dynamics of pyrazole‐embedded thiazolidin‐4‐one hybrids. Archiv der Pharmazie, 356, (3), e2200444. doi:10.1002/ardp.202200444.
Hong, Jeongpyo, Duc, Nguyen Minh, Jeong, Byeong-Chul, Cho, Sanghyun, Shetye, Gauri, Cao, Jin, Lee, Hyun, Jeong, Cherlhyun, Lee, Hanki, Suh, Joo-Won. (2023). Identification of the inhibitory mechanism of ecumicin and rufomycin 4-7 on the proteolytic activity of Mycobacterium tuberculosis ClpC1/ClpP1/ClpP2 complex. Tuberculosis, 138, 102298. doi:10.1016/j.tube.2022.102298.
Liu, Rui, Marshall, Kate, Ma, Rui, Lien Thi Pham, Kim, Shetye, Gauri, Liu, Zhihao, Cho, Sanghyun, Jeong, Hyunyoung, Franzblau, Scott G, Moraski, Garrett C, Miller, Marvin J. (2022). Syntheses and studies of deuterated Imdiazo[1,2-a]pyridine-3-carboxamides with potent anti-tuberculosis activity and improved metabolic properties. Bioorganic Chemistry, 128, 106074. doi:10.1016/j.bioorg.2022.106074.