Photo of Joanna E. Burdette

Joanna E. Burdette


Professor, College of Pharmacy - Pharmaceutical Sciences
Associate Dean for Research, College of Pharmacy - Pharmaceutical Sciences

Contact

Address:

900 S. Ashland Ave Room 3202, Chicago, IL

Office Phone:

(312) 996-6153

Related Sites:

About

Overview:
I am currently a Professor and also the Associate Dean for Research and Graduate Education in the College of Pharmacy at UIC. I am also the co-director of the NIH CCTS KL2 mentoring program for junior faculty. My lab has helped to validate that the major cell type giving rise to high grade serous cancer is the fallopian tube and we have also developed isogenic variants of ovarian cancer derived from murine fallopian tube (or oviductal) cells that we use to study key pathways in tumor initiation and metastasis. I am strongly committed to training and received certification in the National Research Mentoring Network mentoring curriculum and its facilitation.

Research Interests:
ovarian cancer
reproductive biology of the fallopian tube
natural products drug discovery
progesterone biology

Teaching and Supervision

PSCI Ph.D. Thesis Research (PSCI 599), 6/14/2021 – 8/6/2021
Doctoral Restch in Med Chem (MDCH 599), 6/14/2021 – 8/6/2021
Doctoral Research in Pharmacog (PMPG 599), 6/14/2021 – 8/6/2021
Doctoral Restch in Med Chem (MDCH 599), 1/11/2021 – 4/30/2021
Doctoral Research in Pharmacog (PMPG 599), 1/11/2021 – 4/30/2021
Doctoral Research in Pharmacog (PMPG 599), 8/24/2020 – 12/4/2020
Research Presentation (PSCI 502), 8/24/2020 – 12/4/2020
Doctoral Restch in Med Chem (MDCH 599), 8/24/2020 – 12/4/2020
Doctoral Research in Pharmacog (PMPG 599), 6/15/2020 – 8/7/2020

Selected Grants

In vivo evaluation of natural product YB-1, Young BioPharma., 1/1/2021 - 12/31/2021, Obligated Amount: $7814; Anticipated Amount: $7814

Incoming MTA - Phylanthusmins interaction with V-ATPase subunits, Ohio State University., 10/20/2020 - 10/19/2021, No Obligated Amount Set; No Anticipated Amount Set

IRACDA at University of Illinois at Chicago, National Institute of General Medical Sciences., 8/10/2020 - 7/31/2025, Obligated Amount: $384681; No Anticipated Amount Set

IRACDA at the University of Illinois at Chicago - Chicago ARea Excellence in Education & Research (UIC-CAREER), National Institutes of Health (National Institute of General Medical Sciences)., 8/10/2020 - 7/31/2025, Obligated Amount: $1005920; Anticipated Amount: $3585311

Discovery of Anticancer Agents of Diverse Natural Origin, Ohio State University., 5/15/2020 - 4/30/2021, Obligated Amount: $191522; Anticipated Amount: $191522

Label free detection strategies for ovarian cancer in the vaginal microenvironment, DOD., 2020 - 2020, No Obligated Amount Set; Anticipated Amount: $250000

Imaging mass spectrometry methodologies for studying the metabolites of cancer metastasis, National Institutes of Health., 2020 - 2025, No Obligated Amount Set; Anticipated Amount: $1472140

Tumor-Derived Extracellular Vesicle in Ovarian Cancer, University of Kansas Medical Center Research Institute Inc.., 1/1/2020 - 12/31/2022, Obligated Amount: $360000; Anticipated Amount: $360000

PCOS and androgen-related disease modeling and drug testing in Multi-organ Integrated Microfluidic Reproductive Platform, Northwestern University., 9/1/2019 - 8/31/2021, Obligated Amount: $467372; Anticipated Amount: $467372

Selected Publications

Colby, AH, Liu, R, Doyle, RP, Merting, A, Zhang, H, Savage, N, Chu, NQ, Hollister, BA, McCulloch, W, Burdette, JE, Pearce, CJ, Liu, K, Oberlies, NH, Colson, YL, Grinstaff, MW. (2021). Pilot-scale production of expansile nanoparticles: Practical methods for clinical scale-up. Journal of Controlled Release, 337, 144-154. doi:10.1016/j.jconrel.2021.07.012.

Al Subeh, ZY, Raja, HA, Burdette, JE, Falkinham, JO, Hemby, SE, Oberlies, NH. (2021). Three diketomorpholines from a Penicillium sp. (strain G1071). Phytochemistry, 189. doi:10.1016/j.phytochem.2021.112830.

Lee, Jung-Ho, Austin, Julia R, Burdette, Joanna E, Murphy, Brian T. (2021). Secoiridoids from Dogwood (Cornus officinalis) Potentiate Progesterone Signaling. Journal of Natural Products. doi:10.1021/acs.jnatprod.1c00516.

Lusk, Hannah, Burdette, Joanna E, Sanchez, Laura M. (2021). Models for measuring metabolic chemical changes in the metastasis of high grade serous ovarian cancer: fallopian tube, ovary, and omentum. Molecular Omics. doi:10.1039/d1mo00074h.

Ren, Y, Wu, S, Burdette, JE, Cheng, X, Kinghorn, AD. (2021). Structural insights into the interactions of digoxin and Na+/K+-ATPase and other targets for the inhibition of cancer cell proliferation. Molecules, 26, (12). doi:10.3390/molecules26123672.

Jackson-Bey, T, Colina, J, Isenberg, BC, Coppeta, J, Urbanek, M, Kim, JJ, Woodruff, TK, Burdette, JE, Russo, A. (2021). Reply: Exposure of human fallopian tube epithelium to elevated testosterone results in alteration of cilia gene expression and beating. Human reproduction (Oxford, England), 36, (6), 1725. doi:10.1093/humrep/deab022.

Al Subeh, ZY, Raja, HA, Maldonado, A, Burdette, JE, Pearce, CJ, Oberlies, NH. (2021). Thielavins: tuned biosynthesis and LR-HSQMBC for structure elucidation. Journal of Antibiotics, 74, (5), 300-306. doi:10.1038/s41429-021-00405-6.

Sun, M, Guo, B, Xu, M, Zhao, M, Onakpa, MM, Wu, Z, Burdette, JE, Che, CT. (2021). (9βH)- And 17-Nor-Pimaranes fromIcacina oliviformis. Journal of Natural Products, 84, (4), 949-955. doi:10.1021/acs.jnatprod.9b01131.

Knowles, SL, Roberts, CD, Augustinović, M, Flores-Bocanegra, L, Raja, HA, Heath-Borrero, KN, Burdette, JE, Falkinham, JO, Pearce, CJ, Oberlies, NH. (2021). Opportunities and Limitations for Assigning Relative Configurations of Antibacterial Bislactones using GIAO NMR Shift Calculations. Journal of Natural Products, 84, (4), 1254-1260. doi:10.1021/acs.jnatprod.0c01309.

Education

Degrees:
Ph.D, University of Illinois at Chicago, United States
B.S, Emory University, United States

Postgraduate Training:
Physiology, Northwestern University, United States

Selected Presentations

Davis, Lydia, Bisson, Jonathan, Maldonado, Amanda, Burdette, Joanna, Orjala, Jimmy. (2020 August 10). nvestigation of Environmental Regulators of Metabolite Expression from Freshwater Cyanobacteria using Targeted and Untargeted Metabolomic Platforms. Chicago Mass Spec Day.
Davis, Lydia, Sullivan, Peter, Bisson, Jonathan, Kurina, Steven, Burdette, Joanna, Orjala, Jimmy. (2020 May 14). Mapping the Chemical Diversity of a Freshwater Cyanobacterial Library for Enhanced Drug Discovery using Informatic Tools. American Society for Mass Spectrometr.
Davis, Lydia, Maldonado, Amanda, Khin, Manead, Burdette, Joanna, Orjala, Jimmy. (2020 April 24). Discovery of Cytotoxic Isothiazole-containing Alkaloids with FOXO3a Activity from the Cyanobacterium Nostoc sp. UIC 10771. MIKIW Annual Meeting.
Davis, Lydia, Bisson, Jonathan, Sullivan, Peter, Kurina, Steven, Burdette, Joanna, Orjala, Jimmy. (2020 March 03). Discovery of novel chemicals from freshwater cyanobacteria using molecular networking. Pittcon, Annual Meeting.