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Photo of Joanna E. Burdette

Joanna E. Burdette


Professor, College of Pharmacy - Pharmaceutical Sciences
Associate Dean for Research, College of Pharmacy - Pharmaceutical Sciences
Co-Lead Tumor Biology Program, UI Cancer Center

Contact

Address:

900 S. Ashland Ave Room 3202, Chicago, IL

Office Phone:

(312) 996-6153

Related Sites:

About Heading link

Overview:
I am currently the Edward and Josephine Mika Professor and also the Associate Dean for Research and Graduate Education in the College of Pharmacy at UIC. I am also the co-director of the NIH K12 IRACDA postdoc training grant. I also serve as the co-lead for the Tumor Biology Program in the UI Cancer Center. My lab has helped to validate that the major cell type giving rise to high grade serous cancer is the fallopian tube and we have also developed murine fallopian tube (or oviductal) cancer models that we use to study key pathways in tumor initiation and metastasis. I collaborate to study natural products as therapeutic leads in ovarian cancer models. I am strongly committed to training and received certification in the National Research Mentoring Network mentoring curriculum and its facilitation.

Research Interests:
ovarian cancer
reproductive biology of the fallopian tube
natural products drug discovery
progesterone biology

Teaching and Supervision Heading link

PSCI Ph.D. Thesis Research (PSCI 599), 8/22/2022 – 12/2/2022
Research Presentation (PSCI 502), 8/22/2022 – 12/2/2022
Doctoral Research in Pharmacog (PMPG 599), 8/22/2022 – 12/2/2022
Doctoral Research in Pharmacog (PMPG 599), 5/16/2022 – 7/21/2022
Special Proj Pharm Sci (PSCI 390), 1/10/2022 – 4/29/2022
PSCI Ph.D. Thesis Research (PSCI 599), 1/10/2022 – 4/29/2022
Doctoral Restch in Med Chem (MDCH 599), 1/10/2022 – 4/29/2022
Doctoral Research in Pharmacog (PMPG 599), 1/10/2022 – 4/29/2022
Biomedicinal Chemistry (PHAR 423), 1/10/2022 – 4/29/2022

Selected Grants

Development of a small-molecule Beclin1-ATG14L protein-protein interaction inhibitor for cancer therapy, American Cancer Society., 7/1/2022 - 6/30/2026, Obligated Amount: $198000; Anticipated Amount: $792000

Selected Publications

Bergsten, TM, Levy, SE, Zink, KE, Lusk, HJ, Pergande, MR, Cologna, SM, Burdette, JE, Sanchez, LM. (2022). Fallopian tube secreted protein affects ovarian metabolites in high grade serous ovarian cancer. Frontiers in Cell and Developmental Biology, 10. doi:10.3389/fcell.2022.1042734.

El-Elimat, T, Al-Qiam, R, Burdette, JE, Al Sharie, AH, Al-Gharaibeh, M, Oberlies, NH. (2022). Homoisoflavonoids from the bulbs of Bellevalia longipes and an assessment of their potential cytotoxic activity. Phytochemistry, 203. doi:10.1016/j.phytochem.2022.113343.

Russo, A, Zizhao, Y, Heyrman, GM, Cain, BP, Lopez Carrero, A, Isenberg, BC, Dean, MJ, Coppeta, J, Burdette, JE. (2022). Versican secreted by the ovary links ovulation and migration in fallopian tube derived serous cancer. Cancer Letters, 543. doi:10.1016/j.canlet.2022.215779.

Al Subeh, ZY, Li, T, Ustoyev, A, Obike, JC, West, PM, Khin, M, Burdette, JE, Pearce, CJ, Oberlies, NH, Croatt, MP. (2022). Semisynthesis of Hypothemycin Analogues Targeting the C8-C9 Diol. Journal of Natural Products, 85, (8), 2018-2025. doi:10.1021/acs.jnatprod.2c00434.

Lusk, HJ, Levy, SE, Bergsten, TM, Burdette, JE, Sanchez, LM. (2022). Home-Built Spinning Apparatus for Drying Agarose-Based Imaging Mass Spectrometry Samples. Journal of the American Society for Mass Spectrometry, 33, (7), 1325-1328. doi:10.1021/jasms.2c00044.

Cank, KB, Shepherd, RA, Knowles, SL, Rangel-Grimaldo, M, Raja, HA, Bunch, ZL, Cech, NB, Rice, CA, Kyle, DE, Falkinham, JO, Burdette, JE, Oberlies, NH. (2022). Polychlorinated cyclopentenes from a marine derived Periconia sp. (strain G1144). Phytochemistry, 199. doi:10.1016/j.phytochem.2022.113200.

Rodriguez, Galaxia M, Galpin, Kristianne JC, Cook, David P, Yakubovich, Edward, Maranda, Vincent, Macdonald, Elizabeth A, Wilson-Sanchez, Juliette, Thomas, Anjali L, Burdette, Joanna E, Vanderhyden, Barbara C. (2022). The Tumor Immune Profile of Murine Ovarian Cancer Models: An Essential Tool For Ovarian Cancer Immunotherapy Research.. Cancer Research Communications, 2, (6), 417-433. doi:10.1158/2767-9764.crc-22-0017.

Freire, VF, Gubiani, JR, Spencer, TM, Hajdu, E, Ferreira, AG, Ferreira, DAS, De Castro Levatti, EV, Burdette, JE, Camargo, CH, Tempone, AG, Berlinck, RGS. (2022). Feature-Based Molecular Networking Discovery of Bromopyrrole Alkaloids from the Marine Sponge Agelas dispar. Journal of Natural Products, 85, (5), 1340-1350. doi:10.1021/acs.jnatprod.2c00094.

Gubiani, JR, Bernardi, DI, De Paula, CCP, Seleghim, MHR, Ferreira, AG, Batista, ANL, Batista, JM, Oliveira, LFP, Lira, SP, Burdette, JE, Berlinck, RGS. (2022). Absolute configuration of cytotoxic anthraquinones from a Brazilian cave soil-derived fungus, Aspergillus sp. SDC28. Archiv der Pharmazie, 355, (4). doi:10.1002/ardp.202100441.

Selected Presentations

Davis, Lydia, Bisson, Jonathan, Maldonado, Amanda, Burdette, Joanna, Orjala, Jimmy. (2020 August 10). nvestigation of Environmental Regulators of Metabolite Expression from Freshwater Cyanobacteria using Targeted and Untargeted Metabolomic Platforms. Chicago Mass Spec Day.
Davis, Lydia, Sullivan, Peter, Bisson, Jonathan, Kurina, Steven, Burdette, Joanna, Orjala, Jimmy. (2020 May 14). Mapping the Chemical Diversity of a Freshwater Cyanobacterial Library for Enhanced Drug Discovery using Informatic Tools. American Society for Mass Spectrometr.
Davis, Lydia, Maldonado, Amanda, Khin, Manead, Burdette, Joanna, Orjala, Jimmy. (2020 April 24). Discovery of Cytotoxic Isothiazole-containing Alkaloids with FOXO3a Activity from the Cyanobacterium Nostoc sp. UIC 10771. MIKIW Annual Meeting.
Davis, Lydia, Bisson, Jonathan, Sullivan, Peter, Kurina, Steven, Burdette, Joanna, Orjala, Jimmy. (2020 March 03). Discovery of novel chemicals from freshwater cyanobacteria using molecular networking. Pittcon, Annual Meeting.