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Photo of Joanna E. Burdette

Joanna E. Burdette


Professor, College of Pharmacy - Pharmaceutical Sciences
Associate Dean for Research, College of Pharmacy - Pharmaceutical Sciences
Co-Lead Cancer Biology Program, UI Cancer Center
Co-Lead K12 IRACDA Postdoctoral Training, University of Illinois Chicago

Contact

Address:

900 S. Ashland Ave Room 3202, Chicago, IL

Office Phone:

(312) 996-6153

Related Sites:

About Heading link

Overview:
I am currently the Edward and Josephine Mika Professor in the Department of Pharmaceutical Sciences and Associate Dean for Research and Graduate Education in the College of Pharmacy at UIC. I am co-director of the NIH K12 IRACDA postdoc training grant. I serve as the co-lead for the Cancer Biology Program in the UI Cancer Center. My lab helped to validate that the major cell type giving rise to high grade serous cancer is the fallopian tube and we have also developed murine fallopian tube (or oviductal) cancer models that we use to study key pathways in tumor initiation and metastasis. I collaborate to study natural products as therapeutic leads in ovarian cancer models. I am strongly committed to training and received certification in the National Research Mentoring Network mentoring curriculum and its facilitation.

Research Interests:
ovarian cancer
reproductive biology of the fallopian tube
natural products drug discovery
progesterone biology

Teaching and Supervision Heading link

Research Presentation (PSCI 502), 8/21/2023 – 12/1/2023
PSCI Ph.D. Thesis Research (PSCI 599), 8/21/2023 – 12/1/2023
Undergrad Res Exp Pharm Sci (PSCI 300), 8/21/2023 – 12/1/2023
PSCI Ph.D. Thesis Research (PSCI 599), 1/9/2023 – 4/28/2023
Doctoral Research in Pharmacog (PMPG 599), 1/9/2023 – 4/28/2023
Doctoral Research in Pharmacog (PMPG 599), 8/22/2022 – 12/2/2022
PSCI Ph.D. Thesis Research (PSCI 599), 8/22/2022 – 12/2/2022
Research Presentation (PSCI 502), 8/22/2022 – 12/2/2022
Special Proj Pharm Sci (PSCI 390), 1/10/2022 – 4/29/2022

Selected Grants

Tiny proteins in vaginal lavage for early detection of high grade serous ovarian cancer, Foundation for Women's Cancer., 4/1/2023 - 3/31/2024, Obligated Amount: $50000; Anticipated Amount: $50000

Development of a small-molecule Beclin1-ATG14L protein-protein interaction inhibitor for cancer therapy, American Cancer Society., 7/1/2022 - 6/30/2026, Obligated Amount: $198000; Anticipated Amount: $792000

Ovarian and Fallopian Tube Crosstalk via Extracellular Vesicles Promotes the Origin of Ovarian Cancer and the Precancerous Landscape, University of Kansas., 7/1/2022 - 6/30/2024, Obligated Amount: $50000; Anticipated Amount: $50000

Chicago Center for Health and Environment (CACHET), University of Chicago., 6/15/2022 - 3/31/2024, Obligated Amount: $1732094; Anticipated Amount: $1732094

Selected Publications

Gurgul, Aleksandra, Khin, Manead, Souliya, Onevilay, Sydara, Kongmany, Burdette, Joanna E, Johnson, Jeremy J, Che, Chun-Tao. (2024). Acetogenins from the Stem of Uvaria rufa and Their Cytotoxic Activity. Journal of Natural Products. doi:10.1021/acs.jnatprod.3c00838.

Pourhadi, Hadi, El-Elimat, Tamam, Rangel-Grimaldo, Manuel, Graf, Tyler N, Falkinham, Joseph O, Khin, Manead, Burdette, Joanna E, Mirtallo Ezzone, Nathan, Jeyaraj, Jonathan, de Blanco, Esperanza Carcache, Pearce, Cedric J, Oberlies, Nicholas H. (2024). Semisynthesis, characterization, and biological evaluation of fluorinated analogues of the spirobisnaphthalene, diepoxin-η. Tetrahedron Letters, 134, 154857. doi:10.1016/j.tetlet.2023.154857.

Campo, Hannes, Zha, Didi, Pattarawat, Pawat, Colina, Jose, Zhang, Delong, Murphy, Alina, Yoon, Julia, Russo, Angela, Rogers, Hunter B, Lee, Hoi Chang, Zhang, Jiyang, Trotter, Katy, Wagner, Sarah, Ingram, Asia, Pavone, Mary Ellen, Dunne, Sara Fernandez, Boots, Christina E, Urbanek, Margrit, Xiao, Shuo, Burdette, Joanna E, Woodruff, Teresa K, Kim, J Julie. (2023). A new tissue-agnostic microfluidic device to model physiology and disease: the lattice platform. Lab on a Chip, 23, (22), 4821-4833. doi:10.1039/d3lc00378g.

Dipali, Shweta S, Suebthawinkul, Chanakarn, Burdette, Joanna E, Pavone, Mary Ellen, Duncan, Francesca E. (2023). Human follicular fluid elicits select dose- and age-dependent effects on mouse oocytes and cumulus–oocyte complexes in a heterologous in vitro maturation assay. Molecular Human Reproduction, 29, (11), gaad039. doi:10.1093/molehr/gaad039.

Shepherd, Robert A, Earp, Cody E, Cank, Kristof B, Raja, Huzefa A, Burdette, Joanna, Maher, Steven P, Marin, Adriana A, Ruberto, Anthony A, Mai, Sarah Lee, Darveaux, Blaise A, Kyle, Dennis E, Pearce, Cedric J, Oberlies, Nicholas H. (2023). Sheptide A: an antimalarial cyclic pentapeptide from a fungal strain in the Herpotrichiellaceae. The Journal of Antibiotics, 76, (11), 642-649. doi:10.1038/s41429-023-00655-6.

Dipali, Shweta S, King, Christina D, Rose, Jacob P, Burdette, Joanna E, Campisi, Judith, Schilling, Birgit, Duncan, Francesca E. (2023). Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature. Aging, 15, (20), 10821-10855. doi:10.18632/aging.205190.

Maldonado, Amanda C, Haughan, Monica A, Khin, Manead, Ekiert, Julia, Zhang, Ziwei, Lantvit, Daniel, Subeh, Zeinab Y Al, Pierre, Herma C, Salkovski, Maryna, Hirschhorn, Tal, Gao, Yu, Pearce, Cedric J, Stockwell, Brent R, Aldrich, Leslie N, Oberlies, Nicholas H, Burdette, Joanna E. (2023). Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models. Journal of Natural Products, 86, (9), 2102-2110. doi:10.1021/acs.jnatprod.3c00186.

Luu, Gordon T, Ge, Chang, Tang, Yisha, Li, Kailiang, Cologna, Stephanie M, Godwin, Andrew K, Burdette, Joanna E, Su, Judith, Sanchez, Laura M. (2023). An Integrated Approach to Protein Discovery and Detection From Complex Biofluids. Molecular & Cellular Proteomics, 22, (7), 100590. doi:10.1016/j.mcpro.2023.100590.

Ren, Yulin, Kaweesa, Elizabeth N, Tian, Lei, Wu, Sijin, Sydara, Kongmany, Xayvue, Mouachanh, Moore, Curtis E, Soejarto, Djaja D, Cheng, Xiaolin, Yu, Jianhua, Burdette, Joanna E, Kinghorn, A Douglas. (2023). The Cytotoxic Cardiac Glycoside (−)-Cryptanoside A from the Stems of Cryptolepis dubia and Its Molecular Targets. Journal of Natural Products, 86, (6), 1411-1419. doi:10.1021/acs.jnatprod.3c00094.