Photo of Joanna E. Burdette

Joanna E. Burdette


Professor, College of Pharmacy - Pharmaceutical Sciences
Associate Dean for Research, College of Pharmacy - Pharmaceutical Sciences
Co-Lead Tumor Biology Program, UI Cancer Center

Contact

Address:

900 S. Ashland Ave Room 3202, Chicago, IL

Office Phone:

(312) 996-6153

Related Sites:

About

Overview:
I am currently a Professor and also the Associate Dean for Research and Graduate Education in the College of Pharmacy at UIC. I am also the co-director of the NIH K12 IRACDA postdoc training grant. I also serve as the co-lead for the Tumor Biology Program in the UI Cancer Center. My lab has helped to validate that the major cell type giving rise to high grade serous cancer is the fallopian tube and we have also developed isogenic variants of ovarian cancer derived from murine fallopian tube (or oviductal) cells that we use to study key pathways in tumor initiation and metastasis. I am strongly committed to training and received certification in the National Research Mentoring Network mentoring curriculum and its facilitation.

Research Interests:
ovarian cancer
reproductive biology of the fallopian tube
natural products drug discovery
progesterone biology

Teaching and Supervision

Doctoral Research in Pharmacog (PMPG 599), 8/23/2021 – 12/3/2021
Doctoral Restch in Med Chem (MDCH 599), 8/23/2021 – 12/3/2021
Research Presentation (PSCI 502), 8/23/2021 – 12/3/2021
PSCI Ph.D. Thesis Research (PSCI 599), 8/23/2021 – 12/3/2021
Doctoral Research in Pharmacog (PMPG 599), 6/14/2021 – 8/6/2021
Doctoral Restch in Med Chem (MDCH 599), 6/14/2021 – 8/6/2021
PSCI Ph.D. Thesis Research (PSCI 599), 6/14/2021 – 8/6/2021
Doctoral Research in Pharmacog (PMPG 599), 1/11/2021 – 4/30/2021
Doctoral Restch in Med Chem (MDCH 599), 1/11/2021 – 4/30/2021
Principles in Medicinal Chemistry (MDCH 561), 2007 – Present

Selected Publications

Bodke, VV, Burdette, JE. (2021). Advancements in microfluidic systems for the study of female reproductive biology. Endocrinology (United States), 162, (10). doi:10.1210/endocr/bqab078.

Lee, JH, Austin, JR, Burdette, JE, Murphy, BT. (2021). Secoiridoids from Dogwood (Cornus officinalis) Potentiate Progesterone Signaling. Journal of Natural Products, 84, (9), 2612-2616. doi:10.1021/acs.jnatprod.1c00516.

Colby, AH, Liu, R, Doyle, RP, Merting, A, Zhang, H, Savage, N, Chu, NQ, Hollister, BA, McCulloch, W, Burdette, JE, Pearce, CJ, Liu, K, Oberlies, NH, Colson, YL, Grinstaff, MW. (2021). Pilot-scale production of expansile nanoparticles: Practical methods for clinical scale-up. Journal of Controlled Release, 337, 144-154. doi:10.1016/j.jconrel.2021.07.012.

Ren, Y, Wu, S, Chen, S, Burdette, JE, Cheng, X, Kinghorn, AD. (2021). Interaction of (+)-strebloside and its derivatives with na+/k+-atpase and other targets. Molecules, 26, (18). doi:10.3390/molecules26185675.

Al Subeh, ZY, Raja, HA, Burdette, JE, Falkinham, JO, Hemby, SE, Oberlies, NH. (2021). Three diketomorpholines from a Penicillium sp. (strain G1071). Phytochemistry, 189. doi:10.1016/j.phytochem.2021.112830.

Sullivan, P, Krunic, A, Davis, LJ, Kim, HS, Burdette, JE, Orjala, J. (2021). Phormidepistatin from the Cyanobacterium UIC 10484: Assessing the Phylogenetic Distribution of the Statine Pharmacophore. Journal of Natural Products, 84, (8), 2256-2264. doi:10.1021/acs.jnatprod.1c00334.

Lusk, Hannah, Burdette, Joanna E, Sanchez, Laura M. (2021). Models for measuring metabolic chemical changes in the metastasis of high grade serous ovarian cancer: fallopian tube, ovary, and omentum. Molecular Omics. doi:10.1039/d1mo00074h.

Ren, Y, Wu, S, Burdette, JE, Cheng, X, Kinghorn, AD. (2021). Structural insights into the interactions of digoxin and Na+/K+-ATPase and other targets for the inhibition of cancer cell proliferation. Molecules, 26, (12). doi:10.3390/molecules26123672.

Jackson-Bey, T, Colina, J, Isenberg, BC, Coppeta, J, Urbanek, M, Kim, JJ, Woodruff, TK, Burdette, JE, Russo, A. (2021). Reply: Exposure of human fallopian tube epithelium to elevated testosterone results in alteration of cilia gene expression and beating. Human reproduction (Oxford, England), 36, (6), 1725. doi:10.1093/humrep/deab022.

Selected Presentations

Davis, Lydia, Bisson, Jonathan, Maldonado, Amanda, Burdette, Joanna, Orjala, Jimmy. (2020 August 10). nvestigation of Environmental Regulators of Metabolite Expression from Freshwater Cyanobacteria using Targeted and Untargeted Metabolomic Platforms. Chicago Mass Spec Day.
Davis, Lydia, Sullivan, Peter, Bisson, Jonathan, Kurina, Steven, Burdette, Joanna, Orjala, Jimmy. (2020 May 14). Mapping the Chemical Diversity of a Freshwater Cyanobacterial Library for Enhanced Drug Discovery using Informatic Tools. American Society for Mass Spectrometr.
Davis, Lydia, Maldonado, Amanda, Khin, Manead, Burdette, Joanna, Orjala, Jimmy. (2020 April 24). Discovery of Cytotoxic Isothiazole-containing Alkaloids with FOXO3a Activity from the Cyanobacterium Nostoc sp. UIC 10771. MIKIW Annual Meeting.
Davis, Lydia, Bisson, Jonathan, Sullivan, Peter, Kurina, Steven, Burdette, Joanna, Orjala, Jimmy. (2020 March 03). Discovery of novel chemicals from freshwater cyanobacteria using molecular networking. Pittcon, Annual Meeting.