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Photo of Karen I. Sweiss

Karen I. Sweiss


Clinical Assistant Professor, Pharmacy Practice

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PDAT 4: Immunology/Respiratory (PHAR 504), 8/21/2023 – 12/1/2023
PDAT 4: Immunology/Respiratory (PHAR 504), 8/21/2023 – 12/1/2023
Colloquium Lecture Series (PSCI 425), 8/21/2023 – 12/1/2023
Colloquium Lecture Series (PSCI 425), 8/21/2023 – 12/1/2023
PDAT 9: Hematology/Oncology (PHAR 509), 1/9/2023 – 4/28/2023
PDAT 9: Hematology/Oncology (PHAR 509), 1/9/2023 – 4/28/2023
Colloquium Lecture Series (PSCI 425), 8/22/2022 – 12/2/2022
Colloquium Lecture Series (PSCI 425), 8/22/2022 – 12/2/2022
PDAT 4: Immunology/Respiratory (PHAR 504), 8/22/2022 – 12/2/2022

Selected Grants

MC-FludT19-PK: An Open-label, Non-randomized, Prospective Trial to Evaluate the Effect of Renal Function Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics in Patients With AML or MDS Underg, Medac GmbH., 2/9/2024 - 10/29/2029, Obligated Amount: $83791; Anticipated Amount: $83791

Heme-18: Minimal Residual Disease-Guided Post-Autologous Transplant Maintenance with Isatuximab and Lenalidomide in Multiple Myeloma Patients, Sanofi., 6/1/2023 - 11/30/2023, Obligated Amount: $2660818.02; No Anticipated Amount Set

"MC-FludT19-PK: An Open-label, Non-randomized, Prospective Trial to Evaluate the Effect of Renal Function Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics in Patients With AML or MDS Undergoing Allogeneic Hematopoietic Stem Cell Transplantation ", Medexus., 6/1/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

Expand Trial, Allogene., 5/1/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

Monumental-3, Janssen Biotech., 4/1/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

AB-205-301: A Phase 3 Double-Blind, Randomized, Placebo Controlled Study to Evaluate the Efficacy and Safety of AB-205 plus Standard of Care versus Placebo plus Standard of Care in, AB-205-301., 3/3/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

BMS CA057-001: A Phase 3, Two-Stage, Randomized, Multicenter, Open-Label Study Comparing CC-92480, Bortezomib and Dexamethasone (480Vd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Subjects With Relapsed or Refractory Multiple Myeloma (RRMM), BMS CA057-001., 3/1/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

BGB-11417-105: A Phase 1b/2 Dose-Escalation and Cohort-Expansion Study to Determine the Safety and Efficacy of BGB 11417 as Monotherapy, in Combination With Dexamethasone and, Beigene., 2/1/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

CTA: HEME-18 - Post-Autologous Transplant Maintenance with Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma, Genzyme Corp., 8/23/2022 - 10/31/2026, Obligated Amount: $2660821; Anticipated Amount: $2660821

Selected Publications

Sweiss, Karen, Hydren, Jay R, Martinez, Jorge Arturo Hurtado, Sborov, Douglas W, Patel, Pritesh Rajni, Sharp, Lisa, Ahlstrom, Jennifer M, Hofmeister, Craig. (2024). Cannabis and Cannabinoid Use and Perceptions in Patients with Plasma Cell Disorders: A National Healthtree Foundation for Multiple Myeloma Survey. Transplantation and Cellular Therapy, 30, (2), s146-s147. doi:10.1016/j.jtct.2024.01.046.

Sweiss, Karen, Kim, Kyeongmin, Guo, Janet, Hill, Kasey, Abbott, Nicole, Sanchez, Matias E, Uzoka, Chukwuemeka, Quigley, John, Rondelli, Damiano, Sborov, Douglas W, Harvey, R Donald, Nooka, Ajay K, Dhodapkar, Madhav Vishnu, Kaufman, Jonathan L, Joseph, Nisha, Lonial, Sagar, Patel, Pritesh Rajni, Phelps, Mitch A, Hofmeister, Craig. (2024). Mymel: A Phase 1 Trial of AUC-Targeted High Dose Melphalan in Multiple Myeloma Patients Undergoing Autologous Transplant. Transplantation and Cellular Therapy, 30, (2), s168-s169. doi:10.1016/j.jtct.2023.12.216.

Sweiss, Karen, Hofmeister, Craig C, Mohyuddin, Ghulam Rehman, Godara, Amandeep, McClune, Brian, Rondelli, Damiano, Hadidi, Danny, Chan, David, Sanchez, Matias Eugenio, Hai, Min, Phelps, Mitch A, Uzoka, Chukwuemeka, Sborov, Douglas. (2023). RAMP up: Risk Adapted Post-Autologous Transplant Maintenance Therapy in MRD Positive Myeloma Patients. Blood, 142, (Supplement 1), 4974. doi:10.1182/blood-2023-191148.

Rodriguez, Ana Maria Avila, Hadidi, Danny, Hofmeister, Craig C, Quigley, John, Zappia, Maria, Frolov, Maxim, Benevolenskaya, Elizaveta, Sanchez, Matias Eugenio, Kadkol, Shrihari, Sborov, Douglas, Rondelli, Damiano, Uzoka, Chukwuemeka, Sweiss, Karen. (2023). Free from Drug Therapy in Multiple Myeloma (FREEDMM): MRD-Based Cessation of Maintenance. Blood, 142, (Supplement 1), 3395. doi:10.1182/blood-2023-190011.

Maahs, Lucas, Koshy, Matthew, Sweiss, Karen, Ahn, Kang-hyun, Chen, Zhengjia, Uzoka, Chukwuemeka, Galvez, Carlos, Rubinstein, Paul, Quigley, John, Saraf, Santosh L, Rodriguez, Ana Maria Avila, Aydogan, Bulent, Mahmud, Nadim, Rondelli, Damiano. (2023). Addition of Myeloablative Doses of Total Marrow Irradiation (TMI) to Myeloablative Fludarabine/Busulfan Conditioning for Allogeneic HSCT in Patients with High-Risk AML, CML, or Myelodysplastic Syndrome: A Phase II Clinical Trial. Blood, 142, (Supplement 1), 4897. doi:10.1182/blood-2023-179270.

Wagner, Charlotte B, Sweiss, Karen, Anto, Eric, Gonzalez, Rebecca, Puglianini, Omar Alexis Castaneda, Freeman, Ciara Louise L, Ionescu, Filip, Patel, Krina K, Ferreri, Christopher, Gaballa, Mahmoud, Shune, Leyla, McGuirk, Joseph P, Sidana, Surbhi, Hovanky, Vanna, Khouri, Jack, Dima, Danai, Hashmi, Hamza, Davis, James A, Afrough, Aimaz, Kaur, Gurbakhash, Anderson, Larry D, Forsberg, Peter A, Herr, Megan, Hansen, Doris K, Sborov, Douglas, Kocoglu, Mehmet H. (2023). Fludarabine Lymphodepletion Exposure Is Associated with Idecabtagene Vicleucel Toxicity in Relapsed and Refractory Multiple Myeloma Patients: Real-World Experience from the US Myeloma Immunotherapy Consortium. Blood, 142, (Supplement 1), 4880. doi:10.1182/blood-2023-187440.

Nabulsi, Nadia A, Sharp, Lisa K, Sweiss, Karen I, Patel, Pritesh R, Calip, Gregory S, Lee, Todd A. (2023). Patterns of prescription opioid use and opioid-related harms among adult patients with hematologic malignancies.. Journal of Oncology Pharmacy Practice, 10781552231210788. doi:10.1177/10781552231210788.

Rodriguez, Ryan, Joseph, Honey, Macrito, Rosa, Lee, Todd A, Sweiss, Karen. (2023). Risk prediction models for antineoplastic-associated cardiotoxicity in treatment of breast cancer: A systematic review. American Journal of Health-System Pharmacy, 80, (19), 1315-1325. doi:10.1093/ajhp/zxad147.

Sweiss, Karen, Patel, Pritesh, Ahlstrom, Jennifer, Hydren, Jay, Martinez, Jorge Arturo Hurtado, Rodriguez, Ana Maria Avila, Quigley, John, Sharp, Lisa, Calip, Gregory, Rondelli, Damiano, Sborov, Douglas, Hofmeister, Craig. (2023). P-485 Novel observation of the negative effects of persistent chronic opioid use on myeloma survival: a retrospective urban-based cohort study and ongoing prospective HealthTree survey study. Clinical Lymphoma Myeloma & Leukemia, 23, s306-s307. doi:10.1016/s2152-2650(23)02102-x.

Notable Honors

2020, 2020 Best Oral Abstract Award, BMT Pharmacist Conference at the 2020 Transplantation and Cellular Therapy (TCT) Conference

Selected Presentations

Sweiss, Karen. (2023 April 26). Therapeutic Drug Monitoring in BMT. EBMT. Paris, France.
Sweiss, Karen. (2023 April 25). “Novel Strategies for Therapeutic Drug Monitoring of Chemotherapy in Preparative Regimens”. EBMT. Paris France.
Sweiss, Karen. (2023 March 16). Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies in Multiple Myeloma. Sanofi Educational Series.