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Photo of Karen I. Sweiss

Karen I. Sweiss


Clinical Assistant Professor, Pharmacy Practice

Related Sites:

Teaching and Supervision Heading link

Pathobiology of Cancer (PATH 511), 1/8/2024 – 4/26/2024
PDAT 9: Hematology/Oncology (PHAR 509), 1/8/2024 – 4/26/2024
PDAT 9: Hematology/Oncology (PHAR 509), 1/8/2024 – 4/26/2024
PDAT 9: Hematology/Oncology (PHAR 509), 1/8/2024 – 4/26/2024
PDAT 9: Hematology/Oncology (PHAR 509), 1/8/2024 – 4/26/2024
PDAT 9: Hematology/Oncology (PHAR 509), 1/8/2024 – 4/26/2024
PDAT 9: Hematology/Oncology (PHAR 509), 1/8/2024 – 4/26/2024
Colloquium Lecture Series (PSCI 425), 8/21/2023 – 12/1/2023
Colloquium Lecture Series (PSCI 425), 8/21/2023 – 12/1/2023

Selected Grants

MC-FludT19-PK: An Open-label, Non-randomized, Prospective Trial to Evaluate the Effect of Renal Function Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics in Patients With AML or MDS Underg, Medac GmbH., 2/9/2024 - 10/29/2029, Obligated Amount: $83791; Anticipated Amount: $83791

Heme-18: Minimal Residual Disease-Guided Post-Autologous Transplant Maintenance with Isatuximab and Lenalidomide in Multiple Myeloma Patients, Sanofi., 6/1/2023 - 11/30/2023, Obligated Amount: $2660818.02; No Anticipated Amount Set

"MC-FludT19-PK: An Open-label, Non-randomized, Prospective Trial to Evaluate the Effect of Renal Function Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics in Patients With AML or MDS Undergoing Allogeneic Hematopoietic Stem Cell Transplantation ", Medexus., 6/1/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

Expand Trial, Allogene., 5/1/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

Monumental-3, Janssen Biotech., 4/1/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

AB-205-301: A Phase 3 Double-Blind, Randomized, Placebo Controlled Study to Evaluate the Efficacy and Safety of AB-205 plus Standard of Care versus Placebo plus Standard of Care in, AB-205-301., 3/3/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

BMS CA057-001: A Phase 3, Two-Stage, Randomized, Multicenter, Open-Label Study Comparing CC-92480, Bortezomib and Dexamethasone (480Vd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Subjects With Relapsed or Refractory Multiple Myeloma (RRMM), BMS CA057-001., 3/1/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

BGB-11417-105: A Phase 1b/2 Dose-Escalation and Cohort-Expansion Study to Determine the Safety and Efficacy of BGB 11417 as Monotherapy, in Combination With Dexamethasone and, Beigene., 2/1/2023 - Present, No Obligated Amount Set; No Anticipated Amount Set

CTA: HEME-18 - Post-Autologous Transplant Maintenance with Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma, Genzyme Corp., 8/23/2022 - 10/31/2026, Obligated Amount: $2660821; Anticipated Amount: $2660821

Selected Publications

Maahs, Lucas, Patel, Pritesh, Koshy, Matthew, Sweiss, Karen, Chen, Zhengjia, Xu, Ziqiao, Aydogan, Bulent, Rondelli, Damiano. (2024). High dose total marrow irradiation (TMI) does not increase long‐term toxicity of myeloablative fludarabine/busulfan (FluBu4) conditioning regimen in allogeneic hematopoietic stem cell transplantation (HSCT). European Journal Of Haematology. doi:10.1111/ejh.14195.

Sweiss, Karen, Kim, Kyeongmin, Guo, Janet, Hill, Kasey, Abbott, Nicole, Sanchez, Matias E, Uzoka, Chukwuemeka, Quigley, John, Rondelli, Damiano, Sborov, Douglas W, Harvey, R Donald, Nooka, Ajay K, Dhodapkar, Madhav Vishnu, Kaufman, Jonathan L, Joseph, Nisha, Lonial, Sagar, Patel, Pritesh Rajni, Phelps, Mitch A, Hofmeister, Craig. (2024). Mymel: A Phase 1 Trial of AUC-Targeted High Dose Melphalan in Multiple Myeloma Patients Undergoing Autologous Transplant. Transplantation and Cellular Therapy, 30, (2), s168-s169. doi:10.1016/j.jtct.2023.12.216.

Rodriguez, Ana Avila, Hadidi, Danny, Hofmeister, Craig, Quigley, John, Zappia, Maria, Frolov, Maxim, Benevolenskaya, Elizaveta V, Sanchez, Matias, Kadkol, Shrihari, Sborov, Douglas, Rondelli, Damiano, Uzoka, Chukwuemeka, Sweiss, Karen. (2024). Minimal Residual Disease (MRD)-Driven Cessation of Maintenance: Free from Drug Therapy in Multiple Myeloma (FREEDMM trial in progress). Transplantation and Cellular Therapy, 30, (2), s393-s394. doi:10.1016/j.jtct.2023.12.552.

Maahs, Lucas, Koshy, Matthew, Sweiss, Karen, Ahn, Kang-hyun, Chen, Zhengjia, Uzoka, Chukwuemeka, Galvez, Carlos, Rubinstein, Paul, Quigley, John, Saraf, Santosh L, Rodriguez, Ana Avila, Aydogan, Bulent, Mahmud, Nadim, Rondelli, Damiano. (2024). Addition of Myeloablative Doses of Total Marrow Irradiation (TMI) to Myeloablative Fludarabine/Busulfan Conditioning for Allogeneic HSCT in Patients with High-Risk AML, CML, or Myelodysplastic Syndrome: A Phase II Clinical Trial. Transplantation and Cellular Therapy, 30, (2), s162-s163. doi:10.1016/j.jtct.2023.12.207.

Sweiss, Karen, Hydren, Jay R, Martinez, Jorge Arturo Hurtado, Sborov, Douglas W, Patel, Pritesh Rajni, Sharp, Lisa, Ahlstrom, Jennifer M, Hofmeister, Craig. (2024). Cannabis and Cannabinoid Use and Perceptions in Patients with Plasma Cell Disorders: A National Healthtree Foundation for Multiple Myeloma Survey. Transplantation and Cellular Therapy, 30, (2), s146-s147. doi:10.1016/j.jtct.2024.01.046.

Nabulsi, Nadia A, Sharp, Lisa K, Sweiss, Karen I, Patel, Pritesh R, Calip, Gregory S, Lee, Todd A. (2023). Patterns of prescription opioid use and opioid-related harms among adult patients with hematologic malignancies.. Journal of Oncology Pharmacy Practice, 10781552231210788. doi:10.1177/10781552231210788.

Sweiss, Karen, Hofmeister, Craig C, Mohyuddin, Ghulam Rehman, Godara, Amandeep, McClune, Brian, Rondelli, Damiano, Hadidi, Danny, Chan, David, Sanchez, Matias Eugenio, Hai, Min, Phelps, Mitch A, Uzoka, Chukwuemeka, Sborov, Douglas. (2023). RAMP up: Risk Adapted Post-Autologous Transplant Maintenance Therapy in MRD Positive Myeloma Patients. Blood, 142, (Supplement 1), 4974. doi:10.1182/blood-2023-191148.

Maahs, Lucas, Koshy, Matthew, Sweiss, Karen, Ahn, Kang-hyun, Chen, Zhengjia, Uzoka, Chukwuemeka, Galvez, Carlos, Rubinstein, Paul, Quigley, John, Saraf, Santosh L, Rodriguez, Ana Maria Avila, Aydogan, Bulent, Mahmud, Nadim, Rondelli, Damiano. (2023). Addition of Myeloablative Doses of Total Marrow Irradiation (TMI) to Myeloablative Fludarabine/Busulfan Conditioning for Allogeneic HSCT in Patients with High-Risk AML, CML, or Myelodysplastic Syndrome: A Phase II Clinical Trial. Blood, 142, (Supplement 1), 4897. doi:10.1182/blood-2023-179270.

Wagner, Charlotte B, Sweiss, Karen, Anto, Eric, Gonzalez, Rebecca, Puglianini, Omar Alexis Castaneda, Freeman, Ciara Louise L, Ionescu, Filip, Patel, Krina K, Ferreri, Christopher, Gaballa, Mahmoud, Shune, Leyla, McGuirk, Joseph P, Sidana, Surbhi, Hovanky, Vanna, Khouri, Jack, Dima, Danai, Hashmi, Hamza, Davis, James A, Afrough, Aimaz, Kaur, Gurbakhash, Anderson, Larry D, Forsberg, Peter A, Herr, Megan, Hansen, Doris K, Sborov, Douglas, Kocoglu, Mehmet H. (2023). Fludarabine Lymphodepletion Exposure Is Associated with Idecabtagene Vicleucel Toxicity in Relapsed and Refractory Multiple Myeloma Patients: Real-World Experience from the US Myeloma Immunotherapy Consortium. Blood, 142, (Supplement 1), 4880. doi:10.1182/blood-2023-187440.

Notable Honors

2020, 2020 Best Oral Abstract Award, BMT Pharmacist Conference at the 2020 Transplantation and Cellular Therapy (TCT) Conference

Selected Presentations

Sweiss, Karen. (2023 April 26). Therapeutic Drug Monitoring in BMT. EBMT. Paris, France.
Sweiss, Karen. (2023 April 25). “Novel Strategies for Therapeutic Drug Monitoring of Chemotherapy in Preparative Regimens”. EBMT. Paris France.