Mohomed M. Qader
Contact
Address:
833 S Wood St, Chicago, IL
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About
Research Interests:
– Microbial natural products and drug discovery for infectious diseases, specifically for tuberculosis, non-tuberculosis mycobacteria, and Lyme disease
– Development of high throughput workflows for the isolation and prioritization of slow-growing or rare antibiotic-producing microbes from underrepresented environments
– Development of analytical and chromatographic techniques to identify bioactive compounds for scale-up fermentations and lead compound/s identification.
Teaching and Supervision
Selected Publications
Su, Chun, Tuan, Nguyen-Quang, Li, Wen-Hua, Cheng, Jin-Hua, Jin, Ying-Yu, Hong, Soon-Kwang, Lee, Hyun, Qader, Mallique, Klein, Larry, Shetye, Gauri, Pauli, Guido F, Flanzblau, Scott G, Cho, Sang-Hyun, Zhao, Xin-Qing, Suh, Joo-Won. (2025). Enhancing rufomycin production by CRISPR/Cas9-based genome editing and promoter engineering in Streptomyces sp. MJM3502. Synthetic and Systems Biotechnology, 10, (2), 421-432. doi:10.1016/j.synbio.2025.01.002.
Ariyarathna, Pathumi, Wickramarachchi, Dhanushki, Visvanathan, Rizliya, Qader, Mallique, Deen, Afka, Rathnayaka, Isuri, Rateb, Mostafa E, Liyanage, Ruvini. (2025). In vitro anti-diabetic potential of medicinal herbs commonly used in the Ayurvedic system of Sri Lanka with comprehensive metabolite profiling of Phyllanthus emblica using GC-MS and LC-HRMS. Natural Product Research, ahead-of-print, (ahead-of-print), 1-9. doi:10.1080/14786419.2025.2454367.
Qader, Mallique, Mweetwa, Larry L, Rämä, Teppo, Thissera, Bathini, Milne, Bruce F, Abdelmohsen, Usama R, Orfali, Raha, Tawfike, Ahmed, Esheli, Manal, Oluwabusola, Emmanuel T, Jaysainghe, Lalith, Jaspars, Marcel, Rateb, Mostafa E. (2023). Discovery and structural assignment of (S)-sydosine from amphipod-derived Aspergillus sydowii MBC15-11F through HRMS, advanced Mosher, and molecular modelling analyses. Journal of Applied Microbiology, 134, (8), lxad158. doi:10.1093/jambio/lxad158.
Sui, Yixuan, Huang, Xiaoyue, Qader, Mallique, You, Pengtao, Gan, Guoping, Xi, Xueling, Zhang, Jianchao, Cao, Shugeng. (2021). Triterpenoid saponins from the rhizome of Impatiens pritzellii var. hupehensis. Phytochemistry Letters, 41, 175-179. doi:10.1016/j.phytol.2020.12.006.
Villanueva-Silva, Rodrigo, Velez, Patricia, Riquelme, Meritxell, Fajardo-Hernández, Carlos A, Martínez-Cárdenas, Anahí, Arista-Romero, Alejandra, Wan, Baojie, Ma, Rui, Qader, Mallique, Franzblau, Scott G, Figueroa, Mario. Chemical Diversity and Antimicrobial Potential of Cultivable Fungi from Deep-Sea Sediments of the Gulf of Mexico. Molecules, 26, (23), 7328. doi:10.3390/molecules26237328.
Qader, Mallique, Zaman, KH Ahammad Uz, Hu, Zhenquan, Wang, Cong, Wu, Xiaohua, Cao, Shugeng. Aspochalasin H1: A New Cyclic Aspochalasin from Hawaiian Plant-Associated Endophytic Fungus Aspergillus sp. FT1307. Molecules, 26, (14), 4239. doi:10.3390/molecules26144239.
Hamed, Ahmed A, Soldatou, Sylvia, Qader, M Mallique, Arjunan, Subha, Miranda, Kevin Jace, Casolari, Federica, Pavesi, Coralie, Diyaolu, Oluwatofunmilay A, Thissera, Bathini, Eshelli, Manal, Belbahri, Lassaad, Luptakova, Lenka, Ibrahim, Nabil A, Abdel-Aziz, Mohamed S, Eid, Basma M, Ghareeb, Mosad A, Rateb, Mostafa E, Ebel, Rainer. Screening Fungal Endophytes Derived from Under-Explored Egyptian Marine Habitats for Antimicrobial and Antioxidant Properties in Factionalised Textiles. Microorganisms, 8, (10), 1617. doi:10.3390/microorganisms8101617.
Eshelli, Manal, Qader, M Mallique, Jambi, Ebtihaj J, Hursthouse, Andrew S, Rateb, Mostafa E. Current Status and Future Opportunities of Omics Tools in Mycotoxin Research. Toxins, 10, (11), 433. doi:10.3390/toxins10110433.
Lee, Dahae, Yu, Jae Sik, Huang, Peng, Qader, Mallique, Manavalan, Arulmani, Wu, Xiaohua, Kim, Jin-Chul, Pang, Changhyun, Cao, Shugeng, Kang, Ki Sung, Kim, Ki Hyun. Identification of Anti-Inflammatory Compounds from Hawaiian Noni (Morinda citrifolia L.) Fruit Juice. Molecules, 25, (21), 4968. doi:10.3390/molecules25214968.
Education
Degrees:
PhD, University of Peradeniya, Sri Lanka
Postgraduate Training:
Marine microbial natural products, University of the West of Scotland, United Kingdom
Microbial natural products, University of Hawaii at Hilo, United States
Microbial natural products, University of Illinois at Chicago, United States