Photo of Jimmy  Orjala

Jimmy Orjala


Associate Professor of Pharmacognosy, Medicinal Chemistry and Pharmacognosy
Center Affiliate, Center for Biomolecular Sciences

Contact

Building & Room:

3170 MBRB

Address:

900 S Ashland Avenue, Chicago, IL, 60607

Office Phone:

(312) 996-5583

Selected Publications

  • Krunic A, Orjala J. Application of high-field NMR spectroscopy for characterization and quantitation of submilligram quantities of isolated natural products.. Magnetic resonance in chemistry : MRC. 2015;53(12):1043-50. doi:10.1002/mrc.4304.
  • Luo S, Krunic A, Chlipala GE, Orjala J. Microseiramide from the Freshwater Cyanobacterium Microseira sp. UIC 10445.. Phytochemistry letters. 2015;13:47-52. doi:10.1016/j.phytol.2015.05.003.
  • Luo S, Kang HS, Krunic A, Chen W, Yang JL, Woodard JR, Fuchs JG, Hyun Cho SM, Franzblau S, Swanson S, Orjala J. Trichormamides C and D, antiproliferative cyclic lipopeptides from the cultured freshwater cyanobacterium cf. Oscillatoria sp. UIC 10045.. Bioorganic & medicinal chemistry. 2015;23(13):3153-62. doi:10.1016/j.bmc.2015.04.073.
  • Luo S, Kang HS, Krunic A, Chlipala GE, Cai G, Chen WG, Franzblau SM, Swanson S, Orjala J. Carbamidocyclophanes F and G with Anti-Mycobacterium tuberculosis Activity from the Cultured Freshwater Cyanobacterium Nostoc sp.. Tetrahedron letters. 2014;55(3):686-689. doi:10.1016/j.tetlet.2013.11.112.
  • Kim H, Lantvit DD, Hwang CH, Kroll DJ, Swanson SM, Franzblau SG, Orjala J. Indole alkaloids from two cultured cyanobacteria, Westiellopsis sp. and Fischerella muscicola.. Bioorganic & medicinal chemistry. 2012;20(17):5290-5. doi:10.1016/j.bmc.2012.06.030.
  • Kang HS, Santarsiero BD, Kim H, Krunic A, Shen QM, Swanson SD, Chai H, Kinghorn A, Orjala J. Merocyclophanes A and B, antiproliferative cyclophanes from the cultured terrestrial Cyanobacterium Nostoc sp.. Phytochemistry. 2012;79:109-15. doi:10.1016/j.phytochem.2012.03.005.
  • Chlipala GE, Mo S, Orjala J. Chemodiversity in freshwater and terrestrial cyanobacteria – a source for drug discovery.. Current drug targets. 2011;12(11):1654-73.
  • Chlipala GE, Krunic A, Mo S, Sturdy M, Orjala J. CYANOS: a data management system for natural product drug discovery efforts using cultured microorganisms.. Journal of chemical information and modeling. 2011;51(1):171-80. doi:10.1021/ci100280a.
  • Mo S, Krunic AD, Santarsiero BG, Franzblau S, Orjala J. Hapalindole-related alkaloids from the cultured cyanobacterium Fischerella ambigua.. Phytochemistry. 2010;71(17-18):2116-23. doi:10.1016/j.phytochem.2010.09.004.
  • Mo S, Krunic AD, Santarsiero BG, Franzblau S, Orjala J. Hapalindole-related alkaloids from the cultured cyanobacterium Fischerella ambigua.. Phytochemistry. 2010;71(17-18):2116-23. doi:10.1016/j.phytochem.2010.09.004.
  • Chlipala GE, Sturdy M, Krunic AD, Lantvit DM, Shen Q, Porter K, Swanson S, Orjala J. Cylindrocyclophanes with proteasome inhibitory activity from the Cyanobacterium Nostoc sp.. Journal of natural products. 2010;73(9):1529-37. doi:10.1021/np100352e.
  • Chlipala GE, Pham HT, Nguyen VH, Krunic A, Shim SH, Soejarto DD, Orjala J. Nhatrangins A and B, aplysiatoxin-related metabolites from the marine cyanobacterium Lyngbya majuscula from Vietnam.. Journal of natural products. 2010;73(4):784-7. doi:10.1021/np100002q.
  • Mo S, Krunic AD, Pegan SG, Franzblau S, Orjala J. An antimicrobial guanidine-bearing sesterterpene from the cultured cyanobacterium Scytonema sp.. Journal of natural products. 2009;72(11):2043-5. doi:10.1021/np900288x.
  • Guo SK, Tipparaju SD, Pegan S, Wan B, Mo SD, Orjala JG, Mesecar AP, Franzblau S, Kozikowski A. Natural product leads for drug discovery: isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3-a]carbazole based ligands as antibacterial agents.. Bioorganic & medicinal chemistry. 2009;17(20):7126-30. doi:10.1016/j.bmc.2009.08.061.