Photo of Pavel A Petukhov

Pavel A Petukhov

Professor, Medicinal Chemistry and Pharmacognosy
INST AFFL, Institute for Tuberculosis Research


Building & Room:



833 South Wood Street, Chicago, IL, 60612

Office Phone:

(312) 996-4174


Selected Publications

  • Toh MF, Mendonca EL, Eddie SP, Endsley MD, Lantvit DA, Petukhov PE, Burdette J. Kaempferol Exhibits Progestogenic Effects in Ovariectomized Rats.. Journal of steroids & hormonal science. 2014;5(3):136. doi:10.4172/2157-7536.1000136.
  • Abdelkarim HB, Brunsteiner MY, Neelarapu RA, Bai H, Madriaga A, van Breemen R, Blond S, Gaponenko V, Petukhov P. Photoreactive “nanorulers” detect a novel conformation of full length HDAC3-SMRT complex in solution.. ACS chemical biology. 2013;8(11):2538-49. doi:10.1021/cb400601g.
  • Vaidya AS, Neelarapu RB, Madriaga AY, Bai HA, Mendonca E, Abdelkarim H, van Breemen R, Blond S, Petukhov P. Novel histone deacetylase 8 ligands without a zinc chelating group: exploring an ‘upside-down’ binding pose.. Bioorganic & medicinal chemistry letters. 2012;22(21):6621-7. doi:10.1016/j.bmcl.2012.08.104.
  • Vaidya AS, Karumudi B, Mendonca EB, Madriaga AA, Abdelkarim H, van Breemen R, Petukhov P. Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2.. Bioorganic & medicinal chemistry letters. 2012;22(15):5025-30. doi:10.1016/j.bmcl.2012.06.017.
  • Velaparthi S, Brunsteiner MG, Uddin RA, Wan B, Franzblau S, Petukhov P. 5-tert-butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide derivatives as novel potent inhibitors of Mycobacterium tuberculosis pantothenate synthetase: initiating a quest for new antitubercular drugs.. Journal of medicinal chemistry. 2008;51(7):1999-2002. doi:10.1021/jm701372r.
  • Chang MR, Overk CW, Kastrati IH, Peng KA, Yao PL, Qin ZR, Petukhov P, Bolton J, Thatcher G. Estrogenic activity of the equine estrogen metabolite, 4-methoxyequilenin.. Advances in experimental medicine and biology. 2008;617:601-7. doi:10.1007/978-0-387-69080-3_62.
  • Qin ZE, Kastrati IA, Chandrasena RL, Liu HR, Yao P, Petukhov P, Bolton J, Thatcher G. Benzothiophene selective estrogen receptor modulators with modulated oxidative activity and receptor affinity.. Journal of medicinal chemistry. 2007;50(11):2682-92. doi:10.1021/jm070079j.