Photo of Seung Young Lee

Seung Young Lee


Assistant Professor, College of Pharmacy - Pharmaceutical Sciences

Contact

Office Phone:

(312) 413-8294 (work)

Related Sites:

About

Research Interests:
The Lee laboratory aims to develop novel bioengineering tools and methods for pharmaceutical science research investigating cancer, vascular and inflammatory diseases. To better understand and improve pharmaco-kinetics and dynamics of therapeutic agents, we currently focus on developing: 1) Integrated molecular assay platforms; 2) High-throughput computational data analysis systems; and, 3) Combination drug delivery strategies.

Please visit the Lee Group’s Webpage: https://stevelee.lab.uic.edu/

Teaching and Supervision

PSCI Ph.D. Thesis Research (PSCI 599), 1/11/2021 – 4/30/2021
PhD Thesis Research (BPS 599), 1/11/2021 – 4/30/2021
Drug Discovery, Design, and Development (PSCI 501), 9/29/2020 – Present
Pharmaceutics I (PHAR 431), 9/21/2020 – 11/23/2020
PSCI Ph.D. Thesis Research (PSCI 599), 8/24/2020 – 12/4/2020
Pharmaceutics I (PHAR 431), 8/24/2020 – 12/4/2020
Pharmaceutics I (PHAR 431), 8/24/2020 – 12/4/2020
PhD Thesis Research (BPS 599), 8/24/2020 – 12/4/2020
Departmental Seminar (BPS 595), 1/13/2020 – 5/1/2020

Selected Grants

Mechanism of CX3CR1+ macrophage-mediated resolution of eosinophilic allergic lung inflammation, National Institutes of Health (National Heart, Lung, and Blood Institute)., 5/10/2021 - 2/28/2026, Obligated Amount: $585605; Anticipated Amount: $2809500

University of Illinois Cancer Center Pilot Program, UI Cancer Center., 9/1/2020 - 8/31/2021, Obligated Amount: $50000; No Anticipated Amount Set

Transparent Tumor Tomography (T3): Multi-Parameter 3D Imaging for Tumor Immunotherapy, National Institutes of Health (National Institute of Biomedical Imaging and Bioengineering)., 3/15/2019 - 4/30/2022, Obligated Amount: $746997; Anticipated Amount: $746997

Transparent Tumor Tomography (T3): Multi-parameter 3D imaging for tumor immunotherapy, National Institutes of Health., 4/2017 - 10/2018, No Obligated Amount Set; No Anticipated Amount Set

Selected Publications

Phillips, EH, Scholten, D, Flor, AC, Kron, SJ, Lee, SSY. (2021). Multiplexed Tissue Tomography. Methods in Molecular Biology. (pp. 77-93). doi:10.1007/978-1-0716-1593-5_6.

Lee, SSY, Bindokas, VP, Lingen, MW, Kron, SJ. (2019). Nondestructive, multiplex three-dimensional mapping of immune infiltrates in core needle biopsy. Laboratory Investigation, 99, (9), 1400-1413. doi:10.1038/s41374-018-0156-y.

Lee, Steve Seung-Young, Bindokas, Vytautas P, Kron, Stephen J. (2018). Multiplex Three-Dimensional Mapping of Macromolecular Drug Distribution in the Tumor Microenvironment. Molecular Cancer Therapeutics, 18, (1), molcanther.0554.2018. doi:10.1158/1535-7163.mct-18-0554.

Lee, Steve Seung-Young, Bindokas, Vytautas P, Kron, Stephen J. (2017). Multiplex three-dimensional optical mapping of tumor immune microenvironment. Scientific Reports, 7, (1), 17031. doi:10.1038/s41598-017-16987-x.

Lee, Steve Seung-Young, Li, Junjie, Tai, Jien Nee, Ratliff, Timothy L, Park, Kinam, Cheng, Ji-Xin. (2015). Avasimibe Encapsulated in Human Serum Albumin Blocks Cholesterol Esterification for Selective Cancer Treatment. ACS Nano, 9, (3), 2420-2432. doi:10.1021/nn504025a.

Lee, SY, Tyler, JY, Kim, S, Park, K, Cheng, JX. (2013). FRET imaging reveals different cellular entry routes of self-assembled and disulfide bonded polymeric micelles. Molecular Pharmaceutics, 10, (9), 3497-3506. doi:10.1021/mp4003333.

Lee, Seung‐Young, Cheng, Ji‐Xin. (2013). Clearance of Nanoparticles During Circulation. Pharmaceutical Sciences Encyclopedia. (pp. 1-32). doi:10.1002/9780470571224.pse496.

Lee, SY, Kim, S, Tyler, JY, Park, K, Cheng, JX. (2013). Blood-stable, tumor-adaptable disulfide bonded mPEG-(Cys)4-PDLLA micelles for chemotherapy. Biomaterials, 34, (2), 552-561. doi:10.1016/j.biomaterials.2012.09.065.

Lee, So Jin, Huh, Myung Sook, Lee, Seung Young, Min, Solki, Lee, Seulki, Koo, Heebeom, Chu, Jun‐Uk, Lee, Kyung Eun, Jeon, Hyesung, Choi, Yongseok, Choi, Kuiwon, Byun, Youngro, Jeong, Seo Young, Park, Kinam, Kim, Kwangmeyung, Kwon, Ick Chan. (2012). Berichtigung: Tumor‐Homing Poly‐siRNA/Glycol Chitosan Self‐Cross‐Linked Nanoparticles for Systemic siRNA Delivery in Cancer Treatment. Angewandte Chemie, 124, (47), 11830-11830. doi:10.1002/ange.201207703.

Education

Degrees:
PhD, Purdue University, United States, 2014
M.S.E, Gwangju Institute of Science and Technology, South Korea, 2007
B.S.E., Hongik University, South Korea, 2004

Postgraduate Training:
Research Experience, University of Chicago, United States, 2018
Ludwig Center for Metastasis Research, University of Chicago, United States, 2018
Research Experience, Purdue University, United States, 2014

Selected Presentations

Lee, Seung Young. (2020 March 05). Multiplexed 3D Imaging Cytometry for Tumor Microenvironment. UI cancer center TME working group seminar. Chicago, IL.