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Medicinal Chemistry Program

PROGRAM OUTLINE

The Department of Medicinal Chemistry and Pharmacognosy offers a comprehensive and rigorous graduate program in medicinal chemistry leading to M.S. and Ph.D. degrees. Students are only admitted to the Ph.D. program. Medicinal Chemistry is focused on the discovery and development of biologically active agents with potential therapeutic application. The program offers concentrations in analytical and chemical toxicology, biomedicinal chemistry, computational medicinal chemistry, structural biology and synthetic medicinal chemistry. Individual faculty profiles should be consulted for their specific areas of research interest.

The department also offers a graduate program in Pharmacognosy; consult the appropriate heading in the UIC Graduate catalog for more information on that program or contact the DGS, Dr. Jimmy Orjala (pharmacognosy@uic.edu).

ADMISSION REQUIREMENTS

Applicants are considered on an individual basis. In addition to the Graduate College minimum requirements, applicants must meet the following program requirements:

Baccalaureate Field: Pharmacy, chemistry, or the biological sciences. 
Prior academic work should include a year each of biology and organic chemistry.
(Note: No financial support is offered to applicants to the MS program.)
Grade Point Average: At least 3.00 (A=4.00) for the final 60 semester (90 quarter) hours of undergraduate study.
Tests Required: GRE general. The GRE Advanced Chemistry or Biology test is recommended.
Minimum English Competency Test Score:

  • TOEFL 550 (paper-based); 213 (computer-based); or 80, with subscores of Reading 19, Listening 17, Speaking 20, and Writing 21 (iBT Internet-based), OR,
  • IELTS 6.5, with subscores of 6.0 for all four subscores, OR,
  • PTE-Academic 54, with subscores of Reading 51, Listening 47, Speaking 53, and Writing 56.

GRE and TOEFL submission code: 1851
Letters of Recommendation: Three required.
Personal Statement: Required.
Other Requirements: PhD applicants strongly preferred.

DEGREE REQUIREMENTS

In addition to the Graduate College minimum requirements, students must meet the following program requirements:

Master of Science

Minimum Semester Hours Required: 32.
Course work:
 At least 16 hours must be in didactic courses, plus at least 5 hours in MDCH 598
Required Courses: GCLS 501,MDCH 561, MDCH 592 (4 hours) and MDCH 595 (2 hours: 1 hour literature seminar and 1 hour dissertation seminar), plus required concentration and elective courses (minimum of 6 hours)
Program Concentrations: Students must select one of five concentrations:

  • Analytical and Chemical Toxicology
  • Biomedicinal Chemistry
  • Computational Medicinal Chemistry
  • Structural Biology
  • Synthetic Medicinal Chemistry

Required Concentration Courses:

  • Analytical and Chemical Toxicology – MDCH 412, 562, 571
  • Biomedicinal Chemistry – GCLS 502; MDCH 412
  • Computational Medicinal Chemistry – MDCH 572
  • Structural Biology – BCMG(PMPG) 513
  • Synthetic Medicinal Chemistry – MDCH 560, 562, 571.

Recommended Electives:

  • Analytical and Chemical Toxicology – Elective courses selected in consultation with the student’s advisor. Suggested electives include GCLS 502; MDCH 564, 572, and 594; PCOL 505 and 508.
  • Biomedicinal Chemistry – Elective courses selected in consultation with the student’s advisor. Suggested electives include GCLS 503, 504, 505; MDCH 562, 594; BCMG(PMPG) 513, 561, 563; MIM 552.
  • Computational Medicinal Chemistry – elective courses selected in consultation with the student’s advisor. Suggested electives include GCLS 502; MDCH 564, 594; BCMG(PMPG) 513; BIOE 407; CHEM 542 and 558; BSTT 400; CS 559; CS 560.
  • Structural Biology – elective courses selected in consultation with the student’s advisor. Suggested electives include MDCH 412, 562, 571, 572, 594; CHEM 553, 554 and 558; GCLS 502.
  • Synthetic Medicinal Chemistry – elective courses selected in consultation with the student’s advisor. Suggested electives include MDCH 572, 594; CHEM 532, 533, 535, 545 and 553

Examination: Departmental Qualifying Examination: Master’s students may petition the graduate faculty to take this exam. Passing this exam allows the student to proceed toward the Ph.D. without completing a master’s degree.
Thesis or Project: Thesis and oral thesis defense required. No other options available.
Other Requirements: Candidates must TA in one or more of the courses offered by the College of Pharmacy or the Department of Medicinal Chemistry and Pharmacognosy

Doctor of Philosophy

Minimum Semester Hours Required: 96 from the baccalaureate.
Course work: At least 26 semester hours must be in didactic courses.
Required Core Courses: GCLS 501, MDCH 561, MDCH 592 (4 hours) , MDCH 595 (2 hours: 1 hour literature seminar and 1 hour dissertation seminar). 
Program Concentrations: 
Students must select one of five concentrations:

  • Analytical and Chemical Toxicology
  • Biomedicinal Chemistry
  • Computational Medicinal Chemistry
  • Structural Biology
  • Synthetic Medicinal Chemistry

Required Concentration Courses:

  • Analytical and Chemical Toxicology – MDCH 412, 562, 571
  • Biomedicinal Chemistry – GCLS 502; MDCH 412
  • Computational Medicinal Chemistry – MDCH 572
  • Structural Biology – BCMG 513, MDCH 564
  • Synthetic Medicinal Chemistry – MDCH 560, 562, 564, 571, 573.

Recommended Electives:

  • Analytical and Chemical Toxicology – Elective courses selected in consultation with the student’s advisor. Suggested electives include MDCH 572, and 594; PCOL 505 and 508.
  • Biomedicinal Chemistry – Elective courses selected in consultation with the student’s advisor. Suggested electives include GCLS 503, 504, 505; MDCH 562, 594; BCMG 513, 561, 563; MIM 552.
  • Computational Medicinal Chemistry – elective courses selected in consultation with the student’s advisor. Suggested electives include GCLS 502; MDCH 564, 594; BCMG 513; BIOE 407; CHEM 542 and 558; BSTT 400; CS 559; ECE 560.
  • Structural Biology – elective courses selected in consultation with the student’s advisor. Suggested electives include MDCH 412, 562, 571, 572, 594; CHEM 553, 554 and 558; GCLS 502.
  • Synthetic Medicinal Chemistry – elective courses selected in consultation with the student’s advisor. Suggested electives include MDCH 572, 594; CHEM 532, 533, 535, 545 and 553

Examinations:

  • Departmental Qualifying Examination: Required; passing this examination permits doctoral students to bypass the formal requirement of writing a master’s thesis. Good academic standing required for eligibility to take the examination (given following completion of the second semester of required coursework).
  • Preliminary Examination: Required: oral.

Dissertation: Required, including oral defense.
Other Requirements: Candidates must TA in one or more of the courses offered by the College of Pharmacy or the Department of Medicinal Chemistry and Pharmacognosy

APPLICATION PROCEDURES

First you must apply online: http://www.uic.edu/depts/oar/grad/apply_grad_degree.html

PLEASE NOTE: Waiting to submit a complete application for Fall semester after January 1st of that calendar year will substantially reduce the chances of being admitted with an offer of financial support.

The process for the submission of documents has changed.

Beginning with Summer/Fall 2013 applications, applicants no longer submit paper credentials. All applicants are required to upload their documents and academic credentials electronically to satisfy both program-specific requirements and admissions/institutional requirements. Please visit the Graduate Admissions website for more details on the document upload process:http://oar.uic.edu/grad/document_upload

Also fill out and send the request for graduate appointment form, which includes space for your personal statement, to Dr. Thomas:

http://grad.uic.edu/sites/default/files/legacy/pdfs/grad_appt.pdf

FINANCIAL ASSISTANCE

Most students in the program receive financial support as a Teaching or Research Assistant, or as University Fellow.

FELLOWSHIPS

In addition to University-wide competitive fellowships, the Medicinal Chemistry program offers annually an endowed, program-specific competitive fellowship.

ADDITIONAL INFORMATION

For additional information about Graduate Studies in Medicinal Chemistry, please contact:

Douglas D. Thomas, PhD
Director of Graduate Studies in Medicinal Chemistry
College of Pharmacy
University of Illinois at Chicago
833 South Wood Street
539 PHARM, MC 781
Chicago, IL 60612-7231
E-mail: ddthomas@uic.edu

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